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Multi-functional oral small molecule to treat obesity

https://www.science.org/doi/10.1126/sciadv.aed3119
1•bcaulfield•1m ago•0 comments

Doctors are finally learning to manage antidepressant withdrawal

https://www.newscientist.com/article/2584861-antidepressant-withdrawal-symptoms-are-prompting-a-r...
2•eutropheon•5m ago•0 comments

Google Cloud postmortem for us-west1 August incident

https://status.cloud.google.com/incidents/utF3FMFdQfwBzJcGG6vf
3•fastest963•10m ago•0 comments

Show HN: Make apps in seconds inside of sandbox and share them with a link

https://glama.ai/mcp/servers/Reachpad/reachpad-mcp
1•sakuraiben•11m ago•0 comments

What the heck is a context layer

https://nexla.com/what-is-a-context-layer/
1•Debanitrkl•13m ago•0 comments

The advent of capable AI tools has highighted a variant of Simpson's paradox

https://mathstodon.xyz/@tao/117169038028698262
1•ColinWright•14m ago•0 comments

Australia's Nationwide Phone Outage Was an Embarrassing Failure

https://hackaday.com/2026/08/27/australias-nationwide-phone-outage-was-an-embarrassing-failure/
2•anonymousiam•15m ago•1 comments

My GE smart scale's body fat is just 1.5 × BMI − 17.5

https://aiandtractors.com/ge-cs10h-body-fat-formula/
2•Icons8•16m ago•0 comments

Using LLMs to Make the Emacs Web Browser Great Again

https://www.sammystraus.com/#using-llms-to-make-the-emacs-web-browser-great-again
1•sammy0910•16m ago•0 comments

The Night the Earth Shook, Strangers Started to Draw

https://sheets.works/data-viz/strangers-draw-maps
1•sebg•16m ago•0 comments

Intelligence Is the Primitive. Applications Are the Diffusion Layer

https://www.a16z.news/p/intelligence-is-the-primitive-applications
1•gmays•16m ago•0 comments

Running local large language models: not as difficult as you might think

https://vitaexmachina.substack.com/p/running-local-large-language-models
1•sebg•18m ago•0 comments

Ask HN: Note taking app good at Spanish?

1•prios8•18m ago•1 comments

Show HN: OpenTIE and OpenXWA, Modern Ports of Tie Fighter and X-Wing Alliance

https://github.com/elyosh/OpenTIE/
3•elyosh•21m ago•0 comments

Why Are Rivers So Mathematical?

https://www.quantamagazine.org/why-are-rivers-so-mathematical-20260810/
3•sebg•22m ago•0 comments

Buried in Meta's $18B settlement is a legal pass on kids' data

https://techcrunch.com/2026/08/27/buried-in-metas-18b-settlement-is-a-legal-pass-on-kids-data/
5•sbulaev•24m ago•0 comments

Knowledge Health: observability for your knowledge base

https://falconer.com/notes/knowledge-health/
1•fagnerbrack•31m ago•0 comments

Why I Am Right About AI [by Paul "Claude" Gigot]

https://www.theatlantic.com/technology/2026/08/paul-claude-gigot-why-i-am-right-about-ai/688434/
3•samizdis•35m ago•1 comments

Show HN: T2 Linux Touch ID PoC

https://github.com/jmurth1234/t2-touchid-linux
1•jmurth1234•37m ago•0 comments

Situs Inversus

https://en.wikipedia.org/wiki/Situs_inversus
2•sjclemmy•39m ago•0 comments

Show HN: I put 20 ad slots under a Harberger tax

https://anyonecanbuy.com/
2•nadermx•39m ago•0 comments

Show HN: ArtGram – a notation system for abstract paintings

https://artgraph.co/artgram
1•rituraj•44m ago•0 comments

AI's memory crunch is coming for Android apps

https://techcrunch.com/2026/08/27/ais-memory-crunch-is-coming-for-android-apps/
3•627467•44m ago•0 comments

AI Engineer Notebooks – free, framework-free RAG/agents/evals on Colab

https://github.com/calmrocks/ai-engineer-notebooks
2•calmrocks•45m ago•0 comments

I built a pure-Rust headless browser. No Chromium. No V8

https://www.reddit.com/r/webscraping/comments/1w07jov/i_built_a_purerust_headless_browser_no_chro...
2•syumei•45m ago•0 comments

Copyrightability of LLM-generated code: Can we license "vibe code"?

https://fsfe.org/news/2026/news-20260825-01.en.html
3•WhyNotHugo•46m ago•0 comments

Intel previews future instruction-set documentaton

https://intel.github.io/SDM/announcement/2026/08/20/announce-preview.html
2•mmcloughlin•46m ago•0 comments

Outbid case study: auction became the ad (2026)

https://medium.com/@threadotter/outbid-case-study-auction-became-the-ad-2026-719bf85c3c7d
1•threadotter•47m ago•0 comments

Four reproducible vLLM parser failures that return 200 with the wrong tool call

https://ingot.tools/reports/parser-silent-failure
1•glitch003•49m ago•0 comments

Anomalyco/OpenCode, Aider-AI/aider, and Cline Review

https://github.com/anomalyco/opencode
1•paretolaw•51m ago•2 comments
Open in hackernews

What every developer needs to know about in-process databases

https://www.graphgeeks.org/blog/what-every-developer-needs-to-know-about-in-process-dbmss
12•semihs•1y ago

Comments

semihs•1y ago
In-process (aka embedded/embeddable) databases are not new. In fact SQLite is the most widely deployed database in the world. However, starting with DuckDB, there is a new set of in-process database systems, such as Kuzu and Lance. As a co-developer of Kuzu, I hear several frequently asked questions (some of which are misconceptions) about in-process databases.

- What are their advantages/disadvantages compared to client-server databases? - Does in-process mean databases are in-memory/ephemeral? (NO!) - Can in-process databases handle only small amounts of data? (NO!) - What are some common use cases of in-process databases? - What if my application needs a server?

I tried to answer some of these questions in a blog post with pointers to several other resources that articulate several of these points in more detail than I get into.

I hope it's helpful to clarify some of these questions and help developers position in-process DBMSs against client-server ones.

emmanueloga_•1y ago
The article suggests running Kuzu in a FastAPI frontend for network access. A caveat: production Python servers like Uvicorn [1] typically spawn multiple worker processes.

A simple workaround is serving HTTP through a single process language like Go or JavaScript, since Kuzu has bindings for both. Other processes could access the database directly in read-only mode for analysis [2].

For better DX, the ideal would be Kuzu implementing the Bolt protocol of Neo4J directly in the binary, handling single-writer and multi-reader coordination internally. Simpler alternative: port the code from [3] to C++ and add a `kuzu --server` option.

--

1: https://fastapi.tiangolo.com/deployment/server-workers/#mult...

2: https://docs.kuzudb.com/concurrency/#scenario-2-multiple-pro...

3: https://github.com/kuzudb/explorer/tree/master/src/server

semihs•1y ago
Yes this makes sense and we plan to eventually do something along what you are suggesting. We also have a plan to have a built-in server/GUI, where users can directly launch a web-based explorer through our CLI by typing "kuzudb -ui".
emmanueloga_•1y ago
That sounds great!