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Insulin Stored at Room Temperature Does Not Lose Potency (2023)

https://www.healthline.com/health-news/safe-insulin-storage-room-temperature
1•walterbell•1m ago•0 comments

GenAI for Engineers, What's Real, What's Not and What's Coming [video]

https://www.youtube.com/watch?v=BaJ9ROVc2Lk
1•blizow•7m ago•0 comments

LLMs excel at programming–how can they be so bad at it?

https://blog.genesmindsmachines.com/p/llms-excel-at-programminghow-can
1•DeathArrow•8m ago•0 comments

Magnetic Induction Heater Using Flywheel with Neodymium Magnets [video]

https://www.youtube.com/watch?v=jPlyGGVu38U
1•itronitron•10m ago•0 comments

Five books to read this winter

https://www.gatesnotes.com/home/home-page-topic/reader/holiday-books-2025
2•vidyesh•15m ago•0 comments

Topological Turning Points Across Human Lifespan

https://www.nature.com/articles/s41467-025-65974-8
1•DrierCycle•16m ago•0 comments

State of Neuroscience 2025 – Semantic Trend Map

https://stateofneuroscience.thetransmitter.org/map/
2•DrierCycle•19m ago•0 comments

Buy Oxycodone Online: A Complete Guide to Safe Access and Use

https://sites.google.com/view/medixway-pharmacy/medixway-trusted-source-for-every-prescription/
1•christiano90•19m ago•0 comments

US slashes 36% off Medicare spending on 15 high-priced medicines

https://www.reuters.com/business/healthcare-pharmaceuticals/us-negotiated-medicare-prices-15-more...
4•geox•20m ago•0 comments

Code Wiki: Accelerating your code understanding

https://developers.googleblog.com/en/introducing-code-wiki-accelerating-your-code-understanding/
1•geoffbp•23m ago•0 comments

Show HN: RankLens – Track your brand's visibility in AI answers reliably

https://seovendor.co/ranklens-llm-rankings/
1•digitalpeak•24m ago•0 comments

Threatening AI models has no meaningful effect on performance

https://gail.wharton.upenn.edu/research-and-insights/techreport-threaten-or-tip/
1•fzliu•30m ago•0 comments

A Legacy Data Model Dependency Nearly Derailed a Critical Project

https://medium.com/@HobokenDays/the-fate-of-shared-data-model-cf8a3dc88ac9
2•HideInNews•33m ago•0 comments

Meta is helping fraudsters scam you and doesn't care

https://proton.me/blog/meta-scam-ads
4•devonnull•35m ago•0 comments

All Sources of DirectX 12 Documentation

https://asawicki.info/news_1794_all_sources_of_directx_12_documentation
1•ibobev•36m ago•0 comments

LLM-models: a CLI tool to list available LLM models across providers

https://github.com/ljbuturovic/llm-models
1•ljubomir•38m ago•1 comments

Claude Opus 4.5 is in public preview for GitHub Copilot

https://github.blog/changelog/2025-11-24-claude-opus-4-5-is-in-public-preview-for-github-copilot/
1•vyrotek•41m ago•0 comments

Climate activist Greta Thunberg banned from Venice after Grand Canal dyed green

https://abcnews.go.com/International/climate-activist-greta-thunberg-banned-venice-after-grand/st...
1•donsupreme•52m ago•0 comments

Tourist Origins Insights

https://touristorigins.com/
1•jespinoza17•53m ago•0 comments

Improving front end design through Skills

https://www.claude.com/blog/improving-frontend-design-through-skills
2•alwillis•54m ago•0 comments

The Thinking Game

https://youtu.be/d95J8yzvjbQ
1•jonas21•55m ago•0 comments

Robinhood, Susquehanna to Launch Exchange to Expand Prediction Markets Offerings

https://www.wsj.com/finance/robinhood-susquehanna-to-launch-exchange-to-expand-prediction-markets...
1•noitpmeder•57m ago•0 comments

AtlasOS – Optimized Windows

https://atlasos.net/
1•nreece•59m ago•0 comments

Distributed Representations (Geoff Hinton) [pdf]

https://www.cs.toronto.edu/~hinton/absps/pdp3.pdf
1•highfrequency•59m ago•0 comments

Mastering Credit Card Surcharge Laws by State: The Ultimate 2025 Law Firm Guide

https://www.runsensible.com/blog/mastering-credit-card-surcharge-laws/
1•kamaraju•1h ago•0 comments

Show HN: SpreadPaper – span a single wallpaper across multiple macOS monitors

https://github.com/spreadpaper/SpreadPaper
2•biinjo•1h ago•0 comments

Show HN: I engineered a 2mm micro-bearing D20 ring that free-spin for 20 seconds

1•spinity•1h ago•2 comments

Thank You, HN

6•iambateman•1h ago•2 comments

Show HN: SmartMemeSearch – Search memes collections on your computer(CLIP, OCR)

https://github.com/mdimec4/SmartMemeSearch
1•mdimec4•1h ago•0 comments

Show HN: Tickk – Voice task manager for brain dumps (offline, no AI, OSS)

https://tickk.app
1•digi_wares•1h ago•0 comments
Open in hackernews

What every developer needs to know about in-process databases

https://www.graphgeeks.org/blog/what-every-developer-needs-to-know-about-in-process-dbmss
12•semihs•7mo ago

Comments

semihs•7mo ago
In-process (aka embedded/embeddable) databases are not new. In fact SQLite is the most widely deployed database in the world. However, starting with DuckDB, there is a new set of in-process database systems, such as Kuzu and Lance. As a co-developer of Kuzu, I hear several frequently asked questions (some of which are misconceptions) about in-process databases.

- What are their advantages/disadvantages compared to client-server databases? - Does in-process mean databases are in-memory/ephemeral? (NO!) - Can in-process databases handle only small amounts of data? (NO!) - What are some common use cases of in-process databases? - What if my application needs a server?

I tried to answer some of these questions in a blog post with pointers to several other resources that articulate several of these points in more detail than I get into.

I hope it's helpful to clarify some of these questions and help developers position in-process DBMSs against client-server ones.

emmanueloga_•7mo ago
The article suggests running Kuzu in a FastAPI frontend for network access. A caveat: production Python servers like Uvicorn [1] typically spawn multiple worker processes.

A simple workaround is serving HTTP through a single process language like Go or JavaScript, since Kuzu has bindings for both. Other processes could access the database directly in read-only mode for analysis [2].

For better DX, the ideal would be Kuzu implementing the Bolt protocol of Neo4J directly in the binary, handling single-writer and multi-reader coordination internally. Simpler alternative: port the code from [3] to C++ and add a `kuzu --server` option.

--

1: https://fastapi.tiangolo.com/deployment/server-workers/#mult...

2: https://docs.kuzudb.com/concurrency/#scenario-2-multiple-pro...

3: https://github.com/kuzudb/explorer/tree/master/src/server

semihs•7mo ago
Yes this makes sense and we plan to eventually do something along what you are suggesting. We also have a plan to have a built-in server/GUI, where users can directly launch a web-based explorer through our CLI by typing "kuzudb -ui".
emmanueloga_•7mo ago
That sounds great!