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Automating Clinical Trial Landscaping with Edison Analysis

https://edisonscientific.com/articles/automating-clinical-trial-landscaping-with-edison-analysis
1•gmays•2m ago•0 comments

New Sandbox Escape Affecting Popular Node.js Sandbox Library Vm2

https://semgrep.dev/blog/2026/calling-back-to-vm2-and-escaping-sandbox/
1•j12y•3m ago•0 comments

Show HN: Distributed Training Observability for PyTorch (TraceML)

https://github.com/traceopt-ai/traceml
1•traceml-ai•4m ago•0 comments

The Ruby AI Podcast #14: Ruby at 30, AI Agents, and the Cost of Moving Too Fast

https://www.therubyaipodcast.com/2388930/episodes/18571537-new-year-new-ruby-agents-wishes-and-a-...
1•codenamev•4m ago•1 comments

Clawdbot farming up 100 Google Local Guide Accounts

https://twitter.com/indexsy/status/2016039982113132818
1•bhartzer•4m ago•0 comments

The most important thing when working with LLMs

https://steveklabnik.com/writing/the-most-important-thing-when-working-with-llms/
1•shirian•5m ago•0 comments

One Endpoint to Rule Them All: Securing GraphQL in Modern Network Management

https://airheads.hpe.com/blogs/gbanys/2026/01/22/one-endpoint-to-rule-them-all
1•bootbloopers•5m ago•0 comments

HeadsIWin: Why SecureBoot and the Hardware Root of Trust Matter

https://airheads.hpe.com/blogs/nstarke-atl/2025/09/16/headiwin-why-secure-boot-and-the-hardware-r...
1•bootbloopers•5m ago•0 comments

Stellar engines and Dyson bubbles could hold together under the right conditions

https://phys.org/news/2026-01-stellar-dyson-alien-megastructures-conditions.html
1•rbanffy•6m ago•0 comments

Provable Failure of Language Models in Learning Majority Boolean Logic

https://www.alphaxiv.org/abs/2504.04702
1•measurablefunc•6m ago•0 comments

Ultraprocessed Foods and Obesity Risk: A Critical Review of Reported Mechanisms

https://www.sciencedirect.com/science/article/pii/S2161831323002910
1•paulpauper•6m ago•0 comments

Show HN: Agent Composer – Create your own AI rocket scientist agent

https://demo.contextual.ai/
3•jayc481•6m ago•0 comments

It is now 85 seconds to midnight

https://thebulletin.org/doomsday-clock/2026-statement/
2•geox•6m ago•0 comments

Show HN: Runtime AI safety via a continuous "constraint strain" score

https://github.com/willshacklett/gvai-safety-systems
1•PapaShack45•7m ago•0 comments

New US defense strategy downgrades Europe, elevates Greenland

https://www.politico.eu/article/us-national-defense-strategy-downgrade-europe-elevate-greenland-p...
1•maxloh•9m ago•0 comments

Ultraprocessed foods make up to 70% of the US food supply

https://www.cnn.com/2025/02/26/health/ultraprocessed-hyperpalatable-foods-wellness
2•paulpauper•9m ago•0 comments

UnitedHealth forecasts first revenue drop in nearly four decades; shares plunge

https://www.reuters.com/business/healthcare-pharmaceuticals/unitedhealth-forecasts-2026-profit-sl...
2•petethomas•9m ago•0 comments

Tech sector is at lowest share of US employment since early 2021

https://twitter.com/KobeissiLetter/status/2016239033878503684
2•OGEnthusiast•11m ago•0 comments

Why People with a Great Sense of Humor Live Longer

https://www.insidehook.com/longevity/relationship-between-humor-and-longevity
2•RickJWagner•11m ago•0 comments

Ask HN: What are you optimistic about in the age of AI?

1•annodomini2019•12m ago•0 comments

Show HN: DocEndorse – An AI assistant that runs your e-sign workflow in chat

1•kariopaul•13m ago•0 comments

Show HN: A 4.8MB native iOS voice transcriber built with SwiftUI

https://apps.apple.com/us/app/convoxa-ai-meeting-minutes/id6755150446
1•karamalaskar•13m ago•0 comments

Chrome will make popular scripts load faster (by picking winners)

https://danfabulich.medium.com/chrome-will-make-popular-scripts-load-faster-by-picking-winners-bc...
2•dfabulich•13m ago•0 comments

Show HN: We ship Flutter app updates without resubmitting on AppStore

https://github.com/StacDev/stac
1•divyanshub024•14m ago•0 comments

Think Smart About Sparse Compute: LatentMoE for Higher Accuracy per Flop, Param

https://research.nvidia.com/labs/nemotron/LatentMoE/
2•buildbot•14m ago•0 comments

Crabtime, a novel way to write Rust macros

https://ferrisoft.com/blog/crate_crabtime
4•adamnemecek•14m ago•0 comments

Miicrobiome influence on Black Ivory Coffee fermentation in Asian elephants

https://www.nature.com/articles/s41598-025-24196-0
1•PaulHoule•16m ago•0 comments

World War II in Europe with Flags: Every Day

https://www.youtube.com/watch?v=pQrgObFz6uo
1•mahirsaid•16m ago•1 comments

'Ralph Wiggum' loop prompts Claude to vibe-clone commercial software for $10 HR

https://www.theregister.com/2026/01/27/ralph_wiggum_claude_loops/
4•rmason•17m ago•0 comments

How to Nail Big Tech Behavioral Interviews as a Senior Software Engineer

https://newsletter.eng-leadership.com/p/how-to-nail-big-tech-behavioral-interviews
2•rbanffy•19m ago•0 comments
Open in hackernews

What every developer needs to know about in-process databases

https://www.graphgeeks.org/blog/what-every-developer-needs-to-know-about-in-process-dbmss
12•semihs•9mo ago

Comments

semihs•9mo ago
In-process (aka embedded/embeddable) databases are not new. In fact SQLite is the most widely deployed database in the world. However, starting with DuckDB, there is a new set of in-process database systems, such as Kuzu and Lance. As a co-developer of Kuzu, I hear several frequently asked questions (some of which are misconceptions) about in-process databases.

- What are their advantages/disadvantages compared to client-server databases? - Does in-process mean databases are in-memory/ephemeral? (NO!) - Can in-process databases handle only small amounts of data? (NO!) - What are some common use cases of in-process databases? - What if my application needs a server?

I tried to answer some of these questions in a blog post with pointers to several other resources that articulate several of these points in more detail than I get into.

I hope it's helpful to clarify some of these questions and help developers position in-process DBMSs against client-server ones.

emmanueloga_•9mo ago
The article suggests running Kuzu in a FastAPI frontend for network access. A caveat: production Python servers like Uvicorn [1] typically spawn multiple worker processes.

A simple workaround is serving HTTP through a single process language like Go or JavaScript, since Kuzu has bindings for both. Other processes could access the database directly in read-only mode for analysis [2].

For better DX, the ideal would be Kuzu implementing the Bolt protocol of Neo4J directly in the binary, handling single-writer and multi-reader coordination internally. Simpler alternative: port the code from [3] to C++ and add a `kuzu --server` option.

--

1: https://fastapi.tiangolo.com/deployment/server-workers/#mult...

2: https://docs.kuzudb.com/concurrency/#scenario-2-multiple-pro...

3: https://github.com/kuzudb/explorer/tree/master/src/server

semihs•9mo ago
Yes this makes sense and we plan to eventually do something along what you are suggesting. We also have a plan to have a built-in server/GUI, where users can directly launch a web-based explorer through our CLI by typing "kuzudb -ui".
emmanueloga_•9mo ago
That sounds great!