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Vector2Variant: Discovery of Genetic Associations Without Phenotype Engineering

https://www.medrxiv.org/content/10.64898/2026.04.10.26350624v1
1•car•26s ago•0 comments

GetKeys – Create, delete, rotate API keys without visiting a dashboard

https://github.com/weilueluo/getkeys
1•weilueluo•56s ago•0 comments

Looking for a Remote Engineering Role

1•simplisticated•6m ago•0 comments

DEI and Decolonial activists infiltrated NASA; Some are still there

https://twitter.com/brianchau57/status/2111065903471509983
3•MrBuddyCasino•8m ago•0 comments

Show HN: Gridmark – make logos by tweaking shapes on a grid

https://gridmark.dev/
1•mattems•12m ago•0 comments

Ario An experimental framework for explicit epistemic transparency and M0 auditi

https://zenodo.org/records/23305805
1•xx47•14m ago•0 comments

DeepSeek-v4.1-Flash-1017: Wish-Driven Programming Made Real

https://api-docs.deepseek.com/news/news261017/
1•gainsurier•14m ago•0 comments

Show HN: A Game of Life sandbox where any pattern is a shareable link

https://www.seloby.com/life/
2•yooo00•18m ago•0 comments

Survey: How do you create the video demo for your project or product?

1•loveTech•18m ago•0 comments

Trait Causal Models: GWAS, perturbations to predictive models of human biology

https://zenodo.org/records/23426258
1•car•23m ago•0 comments

MAGS: Machine-checked guarantees on specified safety properties in AI code

https://arxiv.org/abs/2609.19391
1•donk8r•26m ago•0 comments

Cellular scaling laws in the mammalian brain

https://www.cell.com/cell/fulltext/S0092-8674(26)01017-2
1•car•26m ago•0 comments

Automattic's New Lawyers Lose Bid for More Time in Legal Fight with WP Engine

https://www.therepository.email/automattics-new-lawyers-lose-bid-for-more-time-in-legal-fight-wit...
1•RobotToaster•30m ago•0 comments

Show HN: Programming Language Cup: same tasks in 32 langs, pick the winner

https://chalmovsky.com/prog-lang-cup/plain/
1•chalmovsky•31m ago•1 comments

Hybrid ML-KEM costs bytes, not CPU: X25519 vs. ML-KEM key exchange benchmark

https://github.com/RayDCodes/pqc-migration-bench
1•ddruhin•31m ago•0 comments

EmbedIDS: Open-source intrusion detection for embedded systems and physical AI

https://embedids.linuscent.com/main/
1•samiralavi•32m ago•0 comments

Ask HN: What was your favourite thread in the last two weeks?

1•Towaway69•37m ago•2 comments

What's IncusOS?

https://linuxcontainers.org/incus-os/introduction/
1•Bluestein•37m ago•0 comments

Show HN: Club Pigeon – A multiplayer pigeon park with SNES-style minigames

https://clubpigeon.lol
2•nilsio•47m ago•0 comments

How Tree Rings Challenged the Myth of American Wilderness

https://www.newyorker.com/science/elements/how-tree-rings-challenged-the-myth-of-american-wilderness
3•bookofjoe•50m ago•1 comments

Deleted AI Chats May Leave Clues Behind

https://news.research.gatech.edu/2026/10/13/deleted-ai-chats-may-leave-clues-behind
1•giuliomagnifico•52m ago•0 comments

General Magic: Oral History of the Influential Tech Company

https://nymag.com/intelligencer/2018/08/general-magic-oral-history-of-the-influential-tech-compan...
1•mpweiher•57m ago•0 comments

Show HN: WGSL linter with Tint parity and a full suite of LSP niceties

https://github.com/elringus/wgsl-linter
1•Elringus•58m ago•0 comments

EU Defence Commissioner Kubilius: Pax Americana Is Over. ^

https://www.reddit.com/r/BuyFromEU/comments/1x7inr3/eu_defence_commissioner_kubilius_pax_american...
3•doener•59m ago•0 comments

Brutal – Framework for Making Games

https://github.com/ahwootech/BRUTAL
2•ivanjermakov•1h ago•0 comments

Photonic Chip Cuts Cost of Hunting Exoplanets (2024)

https://spectrum.ieee.org/photonic-integrated-circuit
1•zeristor•1h ago•0 comments

Rapid alternation of conscious and suppressed representations in primate brains

https://www.biorxiv.org/content/10.64898/2026.10.15.759299v1
2•zby•1h ago•0 comments

Show HN: A web workspace for trying FLUX 3 Klein

https://flux3klein.net
1•xiaosen•1h ago•0 comments

Scaling Indic Pretraining: 2.8T Tokens and an Open Data Generation Pipeline

https://huggingface.co/blog/nvidia/scaling-indic-pretraining
1•porridgeraisin•1h ago•0 comments

Red Dead Redemption 2 – Part 1460 – Old PC [video]

https://www.youtube.com/watch?v=0OfHSE_mhaw
1•doener•1h ago•0 comments
Open in hackernews

What every developer needs to know about in-process databases

https://www.graphgeeks.org/blog/what-every-developer-needs-to-know-about-in-process-dbmss
12•semihs•1y ago

Comments

semihs•1y ago
In-process (aka embedded/embeddable) databases are not new. In fact SQLite is the most widely deployed database in the world. However, starting with DuckDB, there is a new set of in-process database systems, such as Kuzu and Lance. As a co-developer of Kuzu, I hear several frequently asked questions (some of which are misconceptions) about in-process databases.

- What are their advantages/disadvantages compared to client-server databases? - Does in-process mean databases are in-memory/ephemeral? (NO!) - Can in-process databases handle only small amounts of data? (NO!) - What are some common use cases of in-process databases? - What if my application needs a server?

I tried to answer some of these questions in a blog post with pointers to several other resources that articulate several of these points in more detail than I get into.

I hope it's helpful to clarify some of these questions and help developers position in-process DBMSs against client-server ones.

emmanueloga_•1y ago
The article suggests running Kuzu in a FastAPI frontend for network access. A caveat: production Python servers like Uvicorn [1] typically spawn multiple worker processes.

A simple workaround is serving HTTP through a single process language like Go or JavaScript, since Kuzu has bindings for both. Other processes could access the database directly in read-only mode for analysis [2].

For better DX, the ideal would be Kuzu implementing the Bolt protocol of Neo4J directly in the binary, handling single-writer and multi-reader coordination internally. Simpler alternative: port the code from [3] to C++ and add a `kuzu --server` option.

--

1: https://fastapi.tiangolo.com/deployment/server-workers/#mult...

2: https://docs.kuzudb.com/concurrency/#scenario-2-multiple-pro...

3: https://github.com/kuzudb/explorer/tree/master/src/server

semihs•1y ago
Yes this makes sense and we plan to eventually do something along what you are suggesting. We also have a plan to have a built-in server/GUI, where users can directly launch a web-based explorer through our CLI by typing "kuzudb -ui".
emmanueloga_•1y ago
That sounds great!