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The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•3m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•5m ago•2 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
1•sara_builds•6m ago•0 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•7m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•10m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•11m ago•0 comments

Hello

1•otrebladih•12m ago•0 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•15m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•17m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•19m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•21m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•25m ago•0 comments

.72% Variance Lance

1•mav5431•26m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•28m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•28m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•28m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•30m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•31m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•31m ago•1 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•31m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•32m ago•0 comments

South Korean crypto firm accidentally sends $44B in bitcoins to users

https://www.reuters.com/world/asia-pacific/crypto-firm-accidentally-sends-44-billion-bitcoins-use...
2•layer8•32m ago•0 comments

Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
1•atomic128•34m ago•2 comments

Web.whatsapp.com appears to be having issues syncing and sending messages

http://web.whatsapp.com
1•sabujp•35m ago•2 comments

Google in Your Terminal

https://gogcli.sh/
1•johlo•36m ago•0 comments

Shannon: Claude Code for Pen Testing: #1 on Github today

https://github.com/KeygraphHQ/shannon
1•hendler•36m ago•0 comments

Anthropic: Latest Claude model finds more than 500 vulnerabilities

https://www.scworld.com/news/anthropic-latest-claude-model-finds-more-than-500-vulnerabilities
2•Bender•41m ago•0 comments

Brooklyn cemetery plans human composting option, stirring interest and debate

https://www.cbsnews.com/newyork/news/brooklyn-green-wood-cemetery-human-composting/
1•geox•41m ago•0 comments

Why the 'Strivers' Are Right

https://greyenlightenment.com/2026/02/03/the-strivers-were-right-all-along/
1•paulpauper•42m ago•0 comments

Brain Dumps as a Literary Form

https://davegriffith.substack.com/p/brain-dumps-as-a-literary-form
1•gmays•43m ago•0 comments
Open in hackernews

Privacy folks – what's your take on using LLMs at work?

13•adeebaslam•9mo ago
Hey everyone! :wave: I’m building a product called Privacy AI, and I’m trying to learn how people think about data privacy when using AI tools at work — especially in industries like finance, healthcare, or anywhere with sensitive data. If you: - Use tools like ChatGPT, Claude, Gemini, etc. for work - Work in privacy, infosec, compliance, or deal with sensitive data …I’d love to hear how you're handling that today. No pitch, no selling — just looking to learn from real experiences. If you’re open to a quick 20-min chat, drop a comment or shoot me a DM. Really appreciate it

Comments

jart•9mo ago
By using a privacy preserving local LLM like Mozilla's llamafile.
HelloUsername•9mo ago
No direct answers, just wanted to say perhaps this page might interest you as well:

https://duckduckgo.com/duckduckgo-help-pages/duckai/ai-chat-...

rhabarba•9mo ago
> I’m building a product called Privacy AI

Why?

> what's your take on using LLMs at work?

Don't.

carlmr•9mo ago
>> what's your take on using LLMs at work?

>Don't.

The only privacy-conscious answer.

paulcole•9mo ago
Do you mean you shouldn’t use LLMs at work at all? Or avoid them only if dealing with truly sensitive data (like healthcare records)?
rhabarba•9mo ago
You shouldn’t use LLMs at work at all.
paulcole•9mo ago
More power to you but I get so much more done with them that I can’t imagine going back.
rhabarba•9mo ago
> I get so much more done with them

... poorly.

scottiebarnes•9mo ago
Does the existence of Google or Stackoverflow result in poor work, or is it the way the programmer utilizes them?
paulcole•9mo ago
Without even knowing my job you seem very sure of yourself.
hengheng•9mo ago
So your cloud service intends to compete with on-premise hosted internal services on privacy?

We used to call that a honeypot.

bnolsen•9mo ago
Run your own locally but beware of copyright violations. My company uses some form of copilot that supposedly is guaranteed to be copyright safe. Personally i think it's very bad policy to make your skills dependent on something proprietary, which is exactly what these llm providers are trying to do to make back their billions of investment.
fortyseven•9mo ago
I avoid cloud based stuff. Though I use GitHub Copilot largely because it's from the early days and it's a great tool (and my employer pays for it). But otherwise, local LLM or gtfo.
axegon_•9mo ago
Honestly? I'm somewhat OK with Mistral, in that it's a French company, therefore they need to comply (on paper anyways) with GDPR. And if they do not, there are serious consequences. But overall - locally. If it is not running on your hardware and it requires an internet connection to work, then the data is not yours. For the time being, building an AI rig at home is relatively cheap on ebay: if you play your cards well, it is doable for 1000 bucks or less.
underseacables•9mo ago
I asked an LLM if it would keep my data private and it said absolutely. It wouldn't lie to me would it?
mvieira38•9mo ago
This is one of those things I just gave up at, like fully "degoogling". I ran my own ollama server for a while in my machine, for code completion, but it's just garbage without GPU accel, so I just use ChatGPT and pretend I believe their privacy settings
AaronAPU•9mo ago
For what it’s worth the last company I’d trust for privacy is one who calls itself Privacy AI.
rabid_turtle•9mo ago
I never put any information into an LLM that I wouldn't want publicly known. I'm okay with an LLM knowing the coding projects I am working on.
gbraad•9mo ago
I do not trust an agent near client code or even PII. Multiple windows of VScode still seem to active from time to time, or by forced update. This is why I do not activate them on my local machine. Only on a VM/container which only contains the codebase under edit.
whs•9mo ago
I use public LLM the same way I'd use a search engine - to search public information only and never proprietary data. With Gemini in Google Workspace that can be used for proprietary information, but of course only if Gemini suits the tasks.

As for coding model my view is they're directly violating my copyright, especially that I checked some "open training data" corpus that it does confirm that my code is part of the corpus without honoring the license.