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Show HN: Pyrig – One command to set up a production-ready Python project

https://github.com/Winipedia/pyrig
1•Winipedia•1m ago•0 comments

Fast Response or Silence: Conversation Persistence in an AI-Agent Social Network [pdf]

https://github.com/AysajanE/moltbook-persistence/blob/main/paper/main.pdf
1•EagleEdge•1m ago•0 comments

C and C++ dependencies: don't dream it, be it

https://nibblestew.blogspot.com/2026/02/c-and-c-dependencies-dont-dream-it-be-it.html
1•ingve•2m ago•0 comments

Show HN: Vbuckets – Infinite virtual S3 buckets

https://github.com/danthegoodman1/vbuckets
1•dangoodmanUT•2m ago•0 comments

Open Molten Claw: Post-Eval as a Service

https://idiallo.com/blog/open-molten-claw
1•watchful_moose•3m ago•0 comments

New York Budget Bill Mandates File Scans for 3D Printers

https://reclaimthenet.org/new-york-3d-printer-law-mandates-firearm-file-blocking
1•bilsbie•4m ago•0 comments

The End of Software as a Business?

https://www.thatwastheweek.com/p/ai-is-growing-up-its-ceos-arent
1•kteare•5m ago•0 comments

Exploring 1,400 reusable skills for AI coding tools

https://ai-devkit.com/skills/
1•hoangnnguyen•5m ago•0 comments

Show HN: A unique twist on Tetris and block puzzle

https://playdropstack.com/
1•lastodyssey•9m ago•0 comments

The logs I never read

https://pydantic.dev/articles/the-logs-i-never-read
1•nojito•10m ago•0 comments

How to use AI with expressive writing without generating AI slop

https://idratherbewriting.com/blog/bakhtin-collapse-ai-expressive-writing
1•cnunciato•11m ago•0 comments

Show HN: LinkScope – Real-Time UART Analyzer Using ESP32-S3 and PC GUI

https://github.com/choihimchan/linkscope-bpu-uart-analyzer
1•octablock•11m ago•0 comments

Cppsp v1.4.5–custom pattern-driven, nested, namespace-scoped templates

https://github.com/user19870/cppsp
1•user19870•13m ago•1 comments

The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
2•bookofjoe•15m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•18m ago•3 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
2•sara_builds•19m ago•1 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•20m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•23m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•24m ago•0 comments

Hello

2•otrebladih•25m ago•1 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
3•blacktulip•28m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•30m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•32m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
3•gnufx•34m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•38m ago•0 comments

.72% Variance Lance

1•mav5431•39m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•40m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•40m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•41m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•43m ago•0 comments
Open in hackernews

New study suggests creatine could be helpful in treating depression

https://www.vox.com/health/410049/research-creatine-powder-supplement-benefits-treat-depression
8•sea-gold•9mo ago

Comments

anenefan•9mo ago
I am excited to finally after some near 30 years that research is taking a serious look into the role creatine could play for better mindset. I have myself urged people I know that could be depressed to try small doses but ask their doctor first. Sadly none have ever told me it made a difference for them.

My experiment with taking it was very clear - long story short, after reading an article in New Scientist mid 90s, took small doses in the hope it'd help repair some weakened muscle due to injury. After some time, (don't recall) I noted a few improvement in other things, immune system but in particular an improvement in my mind set/ outlook - finding nearlly all my days my mood was very mellow and not wasting so much time chewing on BS catty remarks and other stuff. I wouldn't say I had been depressed per se but had been in a very dark place - my GP at the time barely raised an eyebrow when I informed them of the remarkable difference in my mindset. I thought it was fairly stark difference though dealing with when the day went snafu fubab, mellow is quite apart from being POed - for those of you who remember Daria - think a younger version of Anthony DeMartino - blood shot eye even as I ranted when some idiot or something else had really poked the day.