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Lilly's Zepbound Keeps Weight Off for Three Years, Study Finds

https://www.bloomberg.com/news/articles/2025-04-11/lilly-s-zepbound-keeps-weight-off-for-three-years-study-finds
1•paulpauper•5h ago

Comments

paulpauper•5h ago
There is no evidence to suggest the body ever stops trying to regain the weight, even after 3+ years. Additional approaches are needed to 'reprogram' the brain to not regain the weight and accept the lower weight as the new setpoint.

Starbucks says cutting shop staff in favour of automation has failed

https://www.theguardian.com/business/2025/apr/30/starbucks-says-cutting-shop-staff-in-favour-of-automation-has-failed
1•pseudolus•33s ago•0 comments

108B Pixel Scan of Johannes Vermeer's Girl with a Pearl Earring

https://www.hirox-europe.com/gigapixel/girl-with-a-pearl-earring/
1•twalichiewicz•46s ago•0 comments

Subversiveness and curiosity: what makes Columbo the greatest TV detective

https://crimefictionlover.com/2018/10/subversiveness-and-curiosity-what-makes-columbo-the-greatest-tv-detective/
1•indigodaddy•1m ago•0 comments

How to Fix a Gut Microbiome Ravaged by Antibiotics

https://www.nature.com/articles/d41586-025-01313-7
1•Marceltan•2m ago•0 comments

RFK Jr.'S HHS Orders Lab Studying Deadly Infectious Diseases to Stop Research

https://www.wired.com/story/hhs-niaid-irf-ebola-disease-research-stop/
3•rguiscard•3m ago•0 comments

Release Notes for Safari Technology Preview 218

https://webkit.org/blog/16861/release-notes-for-safari-technology-preview-218/
1•feross•4m ago•0 comments

NIH research findings freely available to the public July 1, 2025

https://www.nih.gov/about-nih/who-we-are/nih-director/statements/accelerating-access-research-results-new-implementation-date-2024-nih-public-access-policy
2•mhb•5m ago•0 comments

Visa Intelligent Commerce: AI Agents That Shop & Pay for You With Your Card

https://www.neowin.net/news/visa-wants-to-give-ai-agents-your-credit-card-so-that-they-can-shop-and-pay-for-you/
1•bundie•5m ago•0 comments

Julia Parsons, U.S. Navy Code Breaker During World War II, Dies at 104

https://www.nytimes.com/2025/04/30/world/julia-parsons-dead.html
1•donohoe•5m ago•0 comments

Thunderscope update: My take: Why open source is better

https://www.crowdsupply.com/eevengers/thunderscope/updates/revving-up-for-production
1•ChuckMcM•6m ago•1 comments

From MCP to multi-agents: The top open source AI projects on GitHub

https://github.blog/open-source/maintainers/from-mcp-to-multi-agents-the-top-10-open-source-ai-projects-on-github-right-now-and-why-they-matter/
1•e2e4•13m ago•0 comments

Office is too slow, so Microsoft is making it load at Windows startup

https://www.pcworld.com/article/2651749/office-is-too-slow-so-microsoft-is-making-it-load-at-windows-startup.html
19•airstrike•16m ago•6 comments

The AI Will See You Now

https://paulmsherman.substack.com/p/the-ai-will-see-you-now
2•paulpauper•17m ago•0 comments

Apple Violated Antitrust Ruling, Judge Finds

https://www.wsj.com/tech/apple-violated-antitrust-ruling-federal-judge-finds-66b85957
61•shayneo•18m ago•9 comments

Exposure to perceptible temperature rise increases concern about climate change

https://theconversation.com/exposure-to-perceptible-temperature-rise-increases-concern-about-climate-change-higher-education-adds-to-understanding-249420
1•PaulHoule•18m ago•0 comments

TesserAct: Learning 4D Embodied World Models

https://arxiv.org/abs/2504.20995
1•badmonster•18m ago•0 comments

Who Betrayed Anne Frank? We May Now Learn the Answer

https://www.thefp.com/p/who-betrayed-anne-frank
1•paulpauper•19m ago•0 comments

The Silent Collapse: Generative AI's Erosion of Photo Licensing Revenue

https://kaptur.co/the-silent-collapse-generative-ais-erosion-of-photo-licensing-revenue/
1•herbertl•19m ago•0 comments

GPT-4o Responds to Negative Feedback

https://thezvi.substack.com/p/gpt-4o-responds-to-negative-feedback
1•paulpauper•22m ago•1 comments

Hire a hacker to recover lost and stolen Bitcoin, Consult Betafort

https://betafort.online/
1•Petersonsmith•22m ago•0 comments

Scrapling v0.2.99 – Easy, effortless Web Scraping With Python as it should be

https://github.com/D4Vinci/Scrapling
1•d4vinci•23m ago•0 comments

Pwning the Ladybird Browser

https://jessie.cafe/posts/pwning-ladybirds-libjs/
10•todsacerdoti•23m ago•0 comments

AI suggestions make writing more generic, Western

https://news.cornell.edu/stories/2025/04/ai-suggestions-make-writing-more-generic-western
1•gnabgib•24m ago•0 comments

DNA links modern pueblo dwellers to Chaco Canyon people

https://arstechnica.com/science/2025/04/dna-links-modern-pueblo-dwellers-to-chaco-canyon-people/
3•bikenaga•25m ago•0 comments

Epic vs. Apple Contempt Order

https://www.documentcloud.org/documents/25924283-epic-v-apple-contempt-order/
3•gpi•25m ago•1 comments

Show HN: I gamefied an AI-powered health optimizer

https://vitalflip.replit.app/
1•KevinRolle•26m ago•1 comments

Russian Colonization of North America

https://en.wikipedia.org/wiki/Russian_colonization_of_North_America
1•diggan•29m ago•0 comments

Swiss army knife of online dev tools

https://devina.io/
1•pseudosavant•30m ago•0 comments

Science, Promise and Peril in the Age of AI

https://www.quantamagazine.org/series/science-in-the-age-of-ai/
1•pseudolus•30m ago•0 comments

Gemini AI video generator powered by Veo 2

https://gemini.google/overview/video-generation/
1•ianrahman•31m ago•0 comments