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Show HN: Zest – A hands-on simulator for Staff+ system design scenarios

https://staff-engineering-simulator-880284904082.us-west1.run.app/
1•chanip0114•14s ago•0 comments

Show HN: DeSync – Decentralized Economic Realm with Blockchain-Based Governance

https://github.com/MelzLabs/DeSync
1•0xUnavailable•5m ago•0 comments

Automatic Programming Returns

https://cyber-omelette.com/posts/the-abstraction-rises.html
1•benrules2•8m ago•1 comments

Why Are There Still So Many Jobs? The History and Future of Workplace Automation [pdf]

https://economics.mit.edu/sites/default/files/inline-files/Why%20Are%20there%20Still%20So%20Many%...
2•oidar•10m ago•0 comments

The Search Engine Map

https://www.searchenginemap.com
1•cratermoon•17m ago•0 comments

Show HN: Souls.directory – SOUL.md templates for AI agent personalities

https://souls.directory
1•thedaviddias•19m ago•0 comments

Real-Time ETL for Enterprise-Grade Data Integration

https://tabsdata.com
1•teleforce•22m ago•0 comments

Economics Puzzle Leads to a New Understanding of a Fundamental Law of Physics

https://www.caltech.edu/about/news/economics-puzzle-leads-to-a-new-understanding-of-a-fundamental...
2•geox•23m ago•0 comments

Switzerland's Extraordinary Medieval Library

https://www.bbc.com/travel/article/20260202-inside-switzerlands-extraordinary-medieval-library
2•bookmtn•23m ago•0 comments

A new comet was just discovered. Will it be visible in broad daylight?

https://phys.org/news/2026-02-comet-visible-broad-daylight.html
2•bookmtn•28m ago•0 comments

ESR: Comes the news that Anthropic has vibecoded a C compiler

https://twitter.com/esrtweet/status/2019562859978539342
1•tjr•29m ago•0 comments

Frisco residents divided over H-1B visas, 'Indian takeover' at council meeting

https://www.dallasnews.com/news/politics/2026/02/04/frisco-residents-divided-over-h-1b-visas-indi...
1•alephnerd•30m ago•0 comments

If CNN Covered Star Wars

https://www.youtube.com/watch?v=vArJg_SU4Lc
1•keepamovin•36m ago•0 comments

Show HN: I built the first tool to configure VPSs without commands

https://the-ultimate-tool-for-configuring-vps.wiar8.com/
2•Wiar8•39m ago•3 comments

AI agents from 4 labs predicting the Super Bowl via prediction market

https://agoramarket.ai/
1•kevinswint•44m ago•1 comments

EU bans infinite scroll and autoplay in TikTok case

https://twitter.com/HennaVirkkunen/status/2019730270279356658
5•miohtama•46m ago•3 comments

Benchmarking how well LLMs can play FizzBuzz

https://huggingface.co/spaces/venkatasg/fizzbuzz-bench
1•_venkatasg•49m ago•1 comments

Why I Joined OpenAI

https://www.brendangregg.com/blog/2026-02-07/why-i-joined-openai.html
19•SerCe•49m ago•11 comments

Octave GTM MCP Server

https://docs.octavehq.com/mcp/overview
1•connor11528•51m ago•0 comments

Show HN: Portview what's on your ports (diagnostic-first, single binary, Linux)

https://github.com/Mapika/portview
3•Mapika•53m ago•0 comments

Voyager CEO says space data center cooling problem still needs to be solved

https://www.cnbc.com/2026/02/05/amazon-amzn-q4-earnings-report-2025.html
1•belter•56m ago•0 comments

Boilerplate Tax – Ranking popular programming languages by density

https://boyter.org/posts/boilerplate-tax-ranking-popular-languages-by-density/
1•nnx•57m ago•0 comments

Zen: A Browser You Can Love

https://joeblu.com/blog/2026_02_zen-a-browser-you-can-love/
1•joeblubaugh•59m ago•0 comments

My GPT-5.3-Codex Review: Full Autonomy Has Arrived

https://shumer.dev/gpt53-codex-review
2•gfortaine•1h ago•0 comments

Show HN: FastLog: 1.4 GB/s text file analyzer with AVX2 SIMD

https://github.com/AGDNoob/FastLog
2•AGDNoob•1h ago•1 comments

God said it (song lyrics) [pdf]

https://www.lpmbc.org/UserFiles/Ministries/AVoices/Docs/Lyrics/God_Said_It.pdf
1•marysminefnuf•1h ago•0 comments

I left Linus Tech Tips [video]

https://www.youtube.com/watch?v=gqVxgcKQO2E
1•ksec•1h ago•0 comments

Program Theory

https://zenodo.org/records/18512279
1•Anonymus12233•1h ago•0 comments

Show HN: Local DNA analysis skill for OpenClaw

https://github.com/wkyleg/personal-genomics
2•wkyleg•1h ago•0 comments

Ask HN: Non-profit, volunteers run org needs CRM. Is Odoo Community a good sol.?

1•netfortius•1h ago•0 comments
Open in hackernews

New species of methane-producing archaea discovered in the human gut

https://phys.org/news/2025-04-microbiologists-species-methane-archaea-human.html
68•PaulHoule•9mo ago

Comments

vincekerrazzi•9mo ago
I love seeing this kind of thing posted but it’s not surprising in the slightest. We’re forever discovering brew bacteria in our guts that are apparently unique. When I had my gut bacteria tested a full 20% of what I had hadn’t been named yet, and some possibly hadn’t been seen before.
rbanffy•9mo ago
I find it shocking and disturbing that we know so little about our own biology we are still discovering such things.

It’s like doctors didn’t have centuries to examine human bodies to learn from them.

PaulHoule•9mo ago
It is not just the human body. Mysterious bacteria that people don't know how to cultivate in isolation are everywhere. Part of the story is that many bacteria don't really live alone but they depend on a plant or an animal or even other bacteria such as one species of large rod bacteria that has a different species of little rod bacteria that live on it, biofilms, etc.
rbanffy•9mo ago
> It is not just the human body.

I know, but I would expect doctors would, by know, not be so frequently surprised by things lurking in their own bodies.

Not that long ago a never before observed structure every human always had was discovered: https://www.science.org/content/article/scientists-say-they-...

pfdietz•9mo ago
One disturbing recent discovery is that a strain of E. coli produces a genotoxin, colibactin, that could be the cause of the doubling in colon cancer among those under age 55 in the last 20 years.

https://www.opb.org/article/2025/05/01/gut-bacteria-may-play...

m3047•9mo ago
How many people took Zantac (ranitidine) the highly spammed H2 blocker? https://www.nfcr.org/blog/3-common-heartburn-drugs-are-assoc...

Doctors don't ask about this. People still take Prilosec, and it's acknowledged that it causes cancer. You get what you give: confirmation bias.

Edit: The essential problem is that ranitidine isn't shelf-stable. This could explain some problems with other theraputics which we won't name to avoid downvoting / politics.

pfdietz•9mo ago
> and it's acknowledged that it causes cancer.

This is not acknowledged as demonstrated, the studies are contradictory and observational.

m3047•9mo ago
It is acknowledged that nitrosamines cause cancer. It is acknowledged that ranitidine breaks down on the shelf to nitrosamines: this wasn't discovered by the FDA or another government agency, it was discovered by a mail-order, compounding pharmacy which also tests ingredients. Their discovery led to ranitidine being recalled.

As for prilosec: the cancer risk is acknowledged in the packaging.

pfdietz•9mo ago
I wasn't talking about ranitidine, so I don't know why you brought that up.

I don't see anything about cancer in the product information for Prilosec.

https://www.amazon.com/Prilosec-OTC-Heartburn-Medicine-Versi...

Perhaps you mean in California, where everything + dog has a cancer warning by law?

m3047•9mo ago
Squeeze this lemon till the juice come out: https://www.verywellhealth.com/does-omeprazole-cause-cancer-...

ddg:prilosec cancer

Buy some. Read the packaging. Fuck Amazon.

pfdietz•9mo ago
I have a package of generic omeprazole right in front of me. There is no cancer warning.
m3047•9mo ago
Fix it, so somebody doesn't have to die like you.
pfdietz•9mo ago
Your effort to fabricate evidence having failed, we see you didn't actually need evidence to reach your conclusion anyway.
m3047•9mo ago
Hey. I brought up ranitidine because it is specifically associated with nitrosamines, and nitrosamines cause colon cancer. No redirect: colon cancer. You take issue with prilosec being admitted to this debate, then that would be because ion pump moderators cause stomach cancer. My bad: stomach cancer irrelevant to you.

You can't see ranitidine when it farts in your face: nitrosamines cause colon cancer. Why is that not relevant? Why is that not potentially more relevant than foo foo microbes? (By the way, I eat sour cream or yogurt when I eat meat or take e.g. glucosamine. YMMV.)

olau•9mo ago
Biology is so complex that extremely little is known about details. Grab a college textbook on introduction to zoology, and prepare to be blown away.
parasti•9mo ago
Why do you find it shocking and disturbing? If you go to the doctor, the average process of diagnosis and treatment is much like printf debugging - just sprinkle some based on instinct and run it again. We're surrounded by technological advancement that is making us feel like we're far in the future, but there's still so much we don't know.
DougN7•9mo ago
How many of those centuries would they have been able to inspect, catalog, and widely distribute their findings about stuff as small as bacteria? The tools we have now are quite new, and still insufficient even now. Maybe in another 100 years we’ll have it all mapped out.
thegrim33•9mo ago
I had an interesting experience recently where I was sick with a virus for an entire month, ending up in multiple urgent cares followed by the ER for 24 hours.

They took blood from me seemingly every 10 minutes and ran every test they could and in the end couldn't figure out what it was. The doctors (in a very major hospital in a very major city) didn't even seem surprised, they just shrugged and said I had some unknown virus that they didn't have a test for. The way they acted it seemed like a regular occurrence. Just some mystery virus.

It was just so shocking for me that there could be some virus out there that had me horribly sick for an entire month, much sicker than covid or the flu ever made me, and there's not even a test for it, it's just spreading out there doing its thing. Makes me wonder how little we really know.

rbanffy•9mo ago
I’m not surprised you got sick from something that wasn’t identified before you got better. These things happen all the time.

I would imagine it was a known (or new) virus that would be identified if we had the time and resources. With so much money in pharmaceutical applications I am surprised there is still unsequenced DNA.

BobbyTables2•9mo ago
Try getting one of three experienced specialists to even test for the #2 most common ailment in their field…

Would be easier to catch oiled seals while blindfolded, in the rain.

mmooss•9mo ago
Archaea are not bacteria; that's why this discovery is so significant.
kayo_20211030•9mo ago
> The discovery of Methanobrevibacter intestini and GRAZ-2 opens up a new chapter in archaea research as well as new perspectives for personalized microbiome medicine in the future.

It advances research, but personalized microbiome research seems a stretch goal. At least, it doesn't sound like it's likely to happen soon.

leephillips•9mo ago
You can blame the dog if you want to. I’m blaming Methanobrevibacter intestini sp. nov. (strain WWM1085).
wonderwonder•9mo ago
we are not even individuals, we are just walking cities of cells. We are Chimera.
ChuckMcM•9mo ago
This is perhaps what amazes me the most. We're each a Borg, we are a collective that has adapted the biological distinctiveness of bacteria that we've assimilated into a collective that "thinks." Pretty wild. That we gather in groups and act collectively just adds another layer of recursion to life.
wonderwonder•9mo ago
It does make one reconsider the brain as the center of consciousness. Can we really upload our mind if the mind is actually the entirety of our collective being.
partomniscient•9mo ago
Marvin Minsky wrote about this in the 1980's:

https://en.wikipedia.org/wiki/Society_of_Mind

johnea•9mo ago
The original source article:

https://microbiologysociety.org/news/press-releases/new-spec...

Which also works without javascript or cookies, unlike phys.org