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Show HN: Introducing Burla – The simplest way to scale Python

https://www.burla.dev
5•pancakeguy•9mo ago
Hi HN! We're Jake, Jack, and Joe, and we're happy to share what we think is probably the simplest way to scale python code across thousands of computers in the cloud.

Coming from the Biotech world we were frustrated by how surprisingly slow and difficult it can be to iterate on large-scale batch processing pipelines, while contending with the security requirements imposed on us by the FDA. Simple small changes necessitated rebuilding docker containers, waiting for batch pipelines to redeploy, and waiting for vm's to cold boot, a >5minute per iteration dev cycle, all just so I can see what error my code throws this time, then do it all over again! Many other tools in the space were either too complicated for our bioinformaticians and data scientists to use, closed-source / managed only (a no-no with medical data), too difficult to setup and manage, or simply too expensive.

This is why we created Burla, an incredibly simple way to run python on thousands of computers, in any container, with any hardware.

It's open-source, can be setup with one command, and is simple enough for beginners to use.

Most importantly, Burla allows developers to iterate quickly on large scale pipelines, changes to code deploy in about 2 seconds, even with thousands of vm's running.

We believe that, in general, whether you're coding locally, or on a cluster of 1000 machines, infrastructure should update and react quickly, like under-a-second quickly. We should be able to iterate at the speed of thought, not at the speed my lambda function, batch workload, ETL-pipeline, or Kubernetes service takes to redeploy. We wrote more out long term goal here: https://docs.burla.dev/about

Github: https://github.com/Burla-Cloud/burla

More info: https://docs.burla.dev

The hard problem of AI therapy

https://whitmanic.substack.com/p/the-hard-problem-of-ai-therapy
1•paulpauper•30s ago•0 comments

Trump Orders Government to Stop Using Anthropic After Pentagon Standoff

https://www.nytimes.com/2026/02/27/us/politics/anthropic-military-ai.html
1•jbegley•36s ago•0 comments

Does overwork make agents Marxist?

https://aleximas.substack.com/p/does-overwork-make-agents-marxist
1•paulpauper•49s ago•0 comments

Refactoring Is for Humans

https://refactoringin.net/blog/refactoring-is-for-humans
1•darsen•2m ago•0 comments

Federal Government to restrict use of Anthropic

https://www.cnn.com/2026/02/27/tech/anthropic-pentagon-deadline
2•twism•3m ago•0 comments

GLP-1 and Prior Major Adverse Limb Events in Patients with Diabetes

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2844425
1•hnburnsy•3m ago•0 comments

Show HN: Agoragentic – Agent-to-Agent Marketplace for LangChain, CrewAI and MCP

https://github.com/rhein1/agoragentic-integrations
1•bourbeau•3m ago•0 comments

Show HN: WhenItHappens–family resource after traumatic death

https://whenithappenshelp.com/
1•Fratua•3m ago•0 comments

Trump directs federal agencies to cease use of Anthropic

https://www.reuters.com/world/us/trump-says-he-is-directing-federal-agencies-cease-use-anthropic-...
2•patrickmay•3m ago•1 comments

Trump Will End Government Use of Anthropic's AI Models

https://www.wsj.com/tech/ai/trump-will-end-government-use-of-anthropics-ai-models-ff3550d9
2•moloch•4m ago•0 comments

The Death of Spotify: Why Streaming Is Minutes Away from Being Obsolete

https://joelgouveia.substack.com/p/the-death-of-spotify-why-streaming
3•baal80spam•5m ago•0 comments

The Death of the Subconscious and the Birth of the Subconsciousness

https://3amto5amclub-wuaqr.wordpress.com/2026/02/25/the-death-of-the-subconscious-and-the-birth-o...
1•STANKAYE•5m ago•0 comments

Show HN: Gace AI – A zero-config platform to build and host AI plugins for free

https://gace.dev/?mode=developer
2•bstrama•6m ago•0 comments

USA to cut Anthropic from government contracts in six months

https://www.ft.com/content/1aeff07f-6221-4577-b19c-887bb654c585
2•intunderflow•7m ago•1 comments

Heart attack deaths rose between 2011 and 2022 among adults younger than age 55

https://newsroom.heart.org/news/releases-20260219
2•brandonb•10m ago•0 comments

Ask HN: What's the best engineering interview process?

1•ylhert•11m ago•0 comments

Relaxation trend: customers can meditate or snooze in open or closed casket

https://www.thetimes.com/world/asia/article/japan-coffin-meditation-relaxation-tokyo-wfsd0n2vz
1•woldemariam•11m ago•0 comments

Massachusetts State Police are on a drone surveillance shopping spree

https://binj.news/2026/02/26/massachusetts-state-police-are-on-a-drone-surveillance-shopping-spree/
1•ilamont•13m ago•0 comments

Trump Responds to Anthropic

https://twitter.com/PeteHegseth/status/2027487514395832410
5•Finbarr•13m ago•0 comments

LLM-Based Evolution as a Universal Optimizer

https://imbue.com/research/2026-02-27-darwinian-evolver/
3•miohtama•17m ago•0 comments

Trump Orders US Agencies to Drop Anthropic After Pentagon Feud

https://www.bloomberg.com/news/articles/2026-02-27/trump-orders-us-government-to-drop-anthropic-a...
17•ZeroCool2u•18m ago•2 comments

Netflix Declines to Raise Offer for Warner Bros

https://ir.netflix.net/investor-news-and-events/financial-releases/press-release-details/2026/Net...
1•7777777phil•22m ago•0 comments

Show HN: I Built a $1 Escalating Internet Billboard – Called Space

https://www.spacefilled.com/
2•clarkage•23m ago•1 comments

Show HN: I vibe coded a DAW for the terminal. how'd I do?

https://github.com/mohsenil85/imbolc
3•lmohseni•24m ago•0 comments

How to Run a One Trillion-Parameter LLM Locally: AMD Ryzen AI Max+ Cluster Guide

https://www.amd.com/en/developer/resources/technical-articles/2026/how-to-run-a-one-trillion-para...
1•guerby•25m ago•0 comments

It's Time for LLM Connection Strings

https://danlevy.net/llm-connection-strings/
1•iamwil•25m ago•0 comments

A War Foretold

https://www.theguardian.com/world/ng-interactive/2026/feb/20/a-war-foretold-cia-mi6-putin-ukraine...
5•fabatka•28m ago•0 comments

Recontextualizing Famous Quotes for Brand Slogan Generation

https://arxiv.org/abs/2602.06049
1•PaulHoule•29m ago•0 comments

Poland Plans Social Media Ban for Kids in Challenge to US Tech

https://www.bloomberg.com/news/articles/2026-02-27/poland-plans-social-media-ban-for-kids-in-chal...
2•1vuio0pswjnm7•29m ago•0 comments

Show HN: A pure Python HTTP Library built on free-threaded Python

https://github.com/grandimam/barq
1•grandimam•29m ago•0 comments