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Hackers meet match: New DNA encryption protects engineered cells from within

https://phys.org/news/2026-04-hackers-dna-encryption-cells.html
1•pseudolus•3m ago•0 comments

High-Level Rust: Getting 80% of the Benefits with 20% of the Pain

https://hamy.xyz/blog/2026-01_high-level-rust
1•maxloh•6m ago•0 comments

Show HN: I benchmarked MCP vs. CLI for browser automation. MCP wins by 25x

https://github.com/HKUDS/CLI-Anything/pull/212
1•Achiyacohen•7m ago•1 comments

"MongoDB is web scale" (Throwback 2010 XtraNormal clip) [video]

https://www.youtube.com/watch?v=b2F-DItXtZs
1•chirau•8m ago•1 comments

Aero and Y2K Webring

https://frutigeraeroarchive.org/aero_webring
1•jack-bodine•9m ago•0 comments

YuanLey YS100-0602T Review a Cheap 8-Port 10GbE Switch

https://www.servethehome.com/yuanley-ys100-0602t-review-a-cheap-8-port-10gbe-switch/
1•teleforce•13m ago•0 comments

Building a Homebrew Computer Like it's 1995 [video]

https://www.youtube.com/watch?v=FVH6_0GlLNc
1•st_goliath•13m ago•0 comments

He Helped Stop Iran from Getting the Bomb

https://www.newyorker.com/magazine/2026/04/06/he-helped-stop-iran-from-getting-the-bomb
2•posthumangr•15m ago•0 comments

USB/IP Project: a general USB device sharing system over IP network

https://usbip.sourceforge.net/
2•ValentineC•16m ago•0 comments

PBS Nova: Terror in Space (1998)

https://www.pbs.org/wgbh/nova/mir/
1•opengrass•19m ago•0 comments

Show HN: I visualized Wasteland as an RTS game

https://gascraft.ai
2•dnewcome•21m ago•0 comments

React-Debug-Updates

https://github.com/pie6k/react-debug-updates
1•handfuloflight•27m ago•0 comments

No Acquittal for Storm Today

https://www.therage.co/roman-storm-acquittal-2/
1•Cider9986•34m ago•0 comments

Hungary 2026 – Chat with 1k AI-simulated voters before the election

https://hungary2026.populon.ai
1•Mert_Predicts•36m ago•0 comments

Hero rat who sniffed out over 100 land mines is honored with giant statue

https://www.washingtonpost.com/lifestyle/2026/04/08/rat-cambodia-statue-land-mines-magawa/
2•paulpauper•40m ago•1 comments

A Brief History of Lab Notebooks

https://www.asimov.press/p/lab-notebooks
4•paulpauper•40m ago•0 comments

Apple Sued by Three YouTube Channels

https://www.macrumors.com/2026/04/06/apple-sued-by-three-youtube-channels/
5•gnabgib•40m ago•3 comments

Forecasting the economic effects of AI

https://forecastingresearch.substack.com/p/forecasting-the-economic-effects-of-ai
1•hhs•41m ago•0 comments

New WHO database helps countries turn health data into better policy

https://www.who.int/europe/news/item/08-04-2026-new-who-database-helps-countries-turn-health-data...
1•gnabgib•42m ago•0 comments

Predict-Rlm: The LLM Runtime That Lets Models Write Their Own Control Flow

https://repo-explainer.com/Trampoline-AI/predict-rlm
1•handfuloflight•43m ago•0 comments

Ask HN: How to have a macOS devcontainer in VS Code?

2•sroussey•43m ago•0 comments

The Exception Butterfly

https://valhovey.github.io/blog/the-exception-butterfly
1•speleo•45m ago•0 comments

Waiting for Postgres 19: Reduced Timing Overhead for EXPLAIN ANALYZE with RDTSC

https://pganalyze.com/blog/5mins-postgres-19-reduced-timing-overhead-explain-analyze
1•lfittl•46m ago•0 comments

1 in 30 – Artemis, Greatness, and Risk

https://1517.substack.com/p/1-in-30-artemis-greatness-and-risk
2•crescit_eundo•47m ago•0 comments

AI will test governments on jobs, training, and public trust

https://www.hoover.org/news/ai-will-test-governments-jobs-training-and-public-trust-hoover-panels...
1•hhs•47m ago•0 comments

Show HN: AMBR.music – Patreon meets TikTok for musicians

https://app.ambr.music/
1•stamc•47m ago•0 comments

Can AI be a 'child of God'? Inside Anthropic's meeting with Christian leaders

https://www.washingtonpost.com/technology/2026/04/11/anthropic-christians-claude-morals/
2•edwardsrobbie•50m ago•0 comments

How to Switch AI Chatbots and Why You Might Want To

https://www.wsj.com/tech/ai/how-to-switch-ai-chatbots-and-why-you-might-want-to-8aaccfd4
1•nanfinitum•51m ago•1 comments

How to break America's great scientific stagnation

https://www.city-journal.org/article/trump-national-science-foundation-nominee-jim-oneill
1•hhs•51m ago•0 comments

Telegram as an Agent Control Plane

https://vita-reports.ham.xyz/s/6020b089f389
2•zackham•54m ago•1 comments
Open in hackernews

How to get up to speed on software development from the top down

1•dave2299•11mo ago
Hi everyone, I am a non-technical founder. I’ve bootstrapped a tech-enabled services company over the past year that’s growing, profitable, and close to 15K a month in revenue. I, by nature, prefer to be involved in the weeds of what’s happening in each domain of my business at first, even if that results in slower business growth. I built my company with a white label portal software (Copilot.app), Airtable, Squarespace, AppSheet,and some ChatGPT scripts.

Now, I need to start building out custom tools. I want to take a deep dive into software development, starting with front and back end web development from the top down, rather than starting from the bottom up as a coder.

If I keep growing eventually I will end up bringing on technical employees, but I want to understand the lay of the land before I start down that road, and I found that I’m able to do a lot once I understand the domain using low code and no code tools. So for example, things like Retool, etc. will accomplish most of the next phase of building I need. But I want to have a reading list of 10 or 20 books or blogs or courses or podcast, etc.. That will help me start getting the way of the land on how to architect software.

I know basic python, basics of the building blocks of programming at the intro level. I just read Designing Data-Intensive Applications (2nd ed on O’Reilly). Does someone have a list of 10 modern books that would help me understand big picture topics like this?

Comments

sherdil2022•11mo ago
I offer personal / 1:1 training, mentoring and technical consultancy for founders and co-founders.

Please feel free to reach out to me. My throwaway email is in my profile, and I will respond.