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Show HN: A unique twist on Tetris and block puzzle

https://playdropstack.com/
1•lastodyssey•2m ago•0 comments

The logs I never read

https://pydantic.dev/articles/the-logs-i-never-read
1•nojito•3m ago•0 comments

How to use AI with expressive writing without generating AI slop

https://idratherbewriting.com/blog/bakhtin-collapse-ai-expressive-writing
1•cnunciato•5m ago•0 comments

Show HN: LinkScope – Real-Time UART Analyzer Using ESP32-S3 and PC GUI

https://github.com/choihimchan/linkscope-bpu-uart-analyzer
1•octablock•5m ago•0 comments

Cppsp v1.4.5–custom pattern-driven, nested, namespace-scoped templates

https://github.com/user19870/cppsp
1•user19870•6m ago•1 comments

The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•9m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•12m ago•3 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
2•sara_builds•12m ago•1 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•13m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•17m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•18m ago•0 comments

Hello

1•otrebladih•19m ago•0 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•22m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•24m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•25m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•27m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•31m ago•0 comments

.72% Variance Lance

1•mav5431•32m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•34m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•34m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•35m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•36m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•37m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•37m ago•2 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•38m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•38m ago•0 comments

South Korean crypto firm accidentally sends $44B in bitcoins to users

https://www.reuters.com/world/asia-pacific/crypto-firm-accidentally-sends-44-billion-bitcoins-use...
2•layer8•39m ago•0 comments

Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
1•atomic128•41m ago•2 comments

Web.whatsapp.com appears to be having issues syncing and sending messages

http://web.whatsapp.com
1•sabujp•41m ago•2 comments

Google in Your Terminal

https://gogcli.sh/
1•johlo•43m ago•0 comments
Open in hackernews

The CL1: the first code deployable biological computer

https://corticallabs.com/cl1.html
54•sprawl_•9mo ago

Comments

dang•9mo ago
This has been posted a few times and looks intriguing, but as far as we can tell, the only there-there is a signup list.

For a good HN thread, we should probably wait until the product is available—or at least for more information?

Edit: looks like there was some sort of earlier discussion at:

Melbourne startup launches 'biological computer' made of human brain cells - https://news.ycombinator.com/item?id=43261218 - March 2025 (37 comments)

The comments are pretty generic, which is the sort of thread we get in the absence of more significant information, so I think waiting is probably the right call. Disagreement is welcome though!

IAmBroom•9mo ago
> there only there-there is a signup list.

Words detected; semantics not found.

dang•9mo ago
Whoops! that should have read "the only there-there". (Fixed now.)

Not sure how much more sense that makes but it's at least what I meant to write :)

comrade1234•9mo ago
Sorry, gotta get home to feed my computer!
andrewmcwatters•9mo ago
Ah man, the computer wet the desk again...
Garlef•9mo ago
... and ate my homework
woodrowbarlow•9mo ago
grown-up tamagotchi.
omneity•9mo ago
"Real neurons" but whose neurons are they sourcing? And are all neurons born equal? Should we have a NeuronArena where people submit samples for eval?

@dang, agreed that the product cannot be discussed on technical merits as of now, but I suggest some of the ancillary topics (irrelevant of their technical implementation) such as neuron sourcing might be worth opening.

nine_k•9mo ago
Since one batch of neurons is expected to survive "up to 6 months", there should be a way to reload it with new neurons. So neuron sourcing should be a recurring concern. The site says: «Real neurons are cultivated inside a nutrient rich solution, supplying them with everything they need to be healthy. They grow across a silicon chip»; this seems to mean that replacing the neurons would require special skills and knowledge, and maybe even a service contract.
throwanem•9mo ago
See those three fluid inlets on the back in the render? Or what look a lot like quick-disconnect hose fittings, at least, and no wonder; this is among other things a life support system for brain tissue, and will minimally need to maintain hydration and exhaust waste. Operating the machine at all will certainly require engineering and environmental services only feasibly available in a professionally staffed and maintained laboratory.

That is one of the reasons why the "buy" CTA dispatches to a contact form. They can and must vet potential customers.

nine_k•9mo ago
Yes, this is a given. I mean that replacing neurons may require a specific knowledge of this machine, and procedures unique to it.

If I were to create such a machine, I'd make the whole top part replaceable, with the bottom part electronic-only. When your neuron culture runs its course, you detach the top part and ship it back to the maker, and buy a new one, with a fresh culture, at a discount. They recycle the top parts by cleaning them and re-populating them with new neurons. The sourcing liability is on them, as is quality control.

throwanem•9mo ago
Oh, I see what you mean. Something like a packaged eluter for short-lived medical isotopes, sure, that makes sense.
genpfault•9mo ago
> the first code deployable biological computer

First? C'mon, Anodyne was doing this back in the mid-80s[1]!

[1]: https://www.mysteryfleshpitnationalpark.com/post/63769988673...

throwanem•9mo ago
Hey, I recognize that robot! That was the Heathkit, wasn't it?
andrewmcwatters•9mo ago
Isn't it weird that they don't actually show what you can do with it?

I mean, I guess they have some capabilities mentioned in papers a few pages back in their website, but it doesn't pass the skink test of, "OK, show me how it works."

IDK, give me an actual code snippet right on the front page, or shut up.

I'm obviously not the target audience, but their marketing is aligned with the sort of "we made this look pretty because we want as many people remotely interested as possible to buy this thing."

Otherwise it could have been a lot more plain, and people seeking out this sort of technology would have found it.

InsideOutSanta•9mo ago
From the website:

> In vitro neurons learn and exhibit sentience when embodied in a simulated gameworld

I can't tell if this whole thing is an art project or a real product.

prettyblocks•9mo ago
It could very well be a brazen scam.
fuentesjr•9mo ago
Also covered in https://www.youtube.com/watch?v=txtDpCLHUkU
WorkerBee28474•9mo ago
We got bio-neural gel packs before GTA 6. Or Half Life 3.
Aaronstotle•9mo ago
Very interesting, I had to re-read it a few times to make sure it was real and not some elaborate prank. I actually wrote a Philosophy paper where there was a computer that had a biological component, and this is almost exactly what I had in mind, very neat to see that there is a company out there making it.
smrtinsert•9mo ago
What in the black mirror...
Proofread0592•9mo ago
Can't wait for the inevitable "this blog is hosted on human brain cells" HN post when someone actually gets their hands on one of these.
jarbus•9mo ago
I can't tell how much computing power this machine has
skulk•9mo ago
The Thought Emporium, a YouTube channel, has some videos that demonstrate how something like this could be built:

Growing Rat neurons to play DOOM (unfinished): part 1 -- https://www.youtube.com/watch?v=bEXefdbQDjw; part 2 -- https://www.youtube.com/watch?v=c-pWliufu6U

Growing human neurons: https://www.youtube.com/watch?v=V2YDApNRK3g