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Wegovy Could Treat Another Chronic Disease

https://www.nytimes.com/2025/04/30/well/wegovy-liver-disease-mash.html
3•bookofjoe•3d ago

Comments

bookofjoe•3d ago
https://archive.ph/84npH
smt88•3d ago
tldr: MASH

> The study, published Wednesday in the New England Journal of Medicine, included 800 adults with a severe form of liver disease known as metabolic dysfunction-associated steatohepatitis, or MASH. People develop MASH after fat builds up in the liver, which can lead to inflammation, cell damage and scarring. The condition, which affects nearly 15 million adults in the United States alone, is one of the most common reasons for liver transplants nationwide. It is closely linked with obesity and Type 2 diabetes, both of which are also on the rise.

pfdietz•3d ago
Not surprising. I was diagnosed with fatty liver associated with metabolic syndrome. The solution wasn't Wegovy, but weight loss by metformin, exercise, and carb restriction. After losing 30 pounds the problem resolved. I imagine weight loss by Wegovy could have the same effect and could be more practical in many cases.

The Surprising Ways That Siblings Shape Our Lives

https://www.nytimes.com/2025/05/06/magazine/siblings-families-parents-influence.html
1•pseudolus•49s ago•1 comments

Show HN: PulseGuard – Free and Smart Uptime Monitoring with EC2 Control

https://pulseguard.in
1•hrshw•1m ago•0 comments

Show HN: Oauth2_capture – A Django package for handling OAuth2 token flows

1•simplecto•1m ago•0 comments

Cloudflare D1 + Metabase = Analytics on a Budget

https://logdy.dev/blog/post/how-to-connect-cloudflare-d1-sqlite-database-with-metabase-for-powerful-analytics
1•piterrro•4m ago•0 comments

The Letter from Georgia O'Keeffe That Changed Yayoi Kusama's Life

https://news.artnet.com/art-world/yayoi-kusama-georgia-okeeffe-pen-pals-2630108
1•bookofjoe•5m ago•0 comments

Plumb

https://useplumb.com/
1•handfuloflight•7m ago•0 comments

Weight-loss drugs cut alcohol intake by almost two-thirds

https://medicalxpress.com/news/2025-05-weight-loss-drugs-alcohol-intake.html
1•geox•9m ago•0 comments

Airlines Are Collecting Your Data and Selling It to ICE

https://www.levernews.com/airlines-are-collecting-your-data-and-selling-it-to-ice/
3•SergeAx•10m ago•0 comments

A new way to automatically deprecate DockerHub repository: Bulk Archive

1•vipulgupta2048_•10m ago•0 comments

Show HN: Postel Voice – Write X posts like your favourite creators

https://www.postel.app
1•JoschuaBuilds•14m ago•0 comments

Andrej Karpathy on X: system Prompt Learning?

https://twitter.com/karpathy/status/1921368644069765486
1•bilsbie•15m ago•0 comments

Test LLM-powered apps in TypeScript

https://www.evalite.dev/
2•vortex_ape•21m ago•0 comments

The importance of virtue in software engineering

https://www.seangoedecke.com/character-in-software-engineering/
1•swah•21m ago•0 comments

Why can't language models come up with new ideas?

https://www.seangoedecke.com/why-cant-ais-have-new-ideas/
1•swah•22m ago•0 comments

The American Elevator Explains Why Housing Costs Have Skyrocketed

https://www.nytimes.com/2024/07/08/opinion/elevator-construction-regulation-labor-immigration.html
1•rmason•34m ago•1 comments

Sand Simulation (Pixel Dynasty)

https://github.com/Goshoon/Pixel-Dynasty
1•Hongo123•34m ago•1 comments

FTC Votes on Negative Option Rule Deadline

https://www.ftc.gov/news-events/news/press-releases/2025/05/ftc-votes-negative-option-rule-deadline
1•impish9208•35m ago•0 comments

Who needs Rust's compiler nanny (Borrow Checker)? C++ devs are not helpless

https://www.youtube.com/watch?v=mmUAdCzrdmQ
1•NuLL3rr0r•35m ago•0 comments

The Giants of Silicon Valley Are Having a Midlife Crisis over AI

https://archive.is/2025.05.10-094755/https://www.wsj.com/tech/ai/the-giants-of-silicon-valley-are-having-a-midlife-crisis-over-ai-74968a07
5•elsewhen•37m ago•1 comments

Ask HN: I became interim CTO and want to avoid dumb fuck-ops

1•oizys_throwaway•37m ago•1 comments

Jony Ive's next product is driven by the 'unintended consequences' of the iPhone

https://www.theverge.com/news/664131/jony-ive-unintended-consequences-iphone-new-product
7•emot•40m ago•2 comments

The Stealthy Lab Cooking Up Amazon's Secret Sauce

https://www.wsj.com/tech/amazon-ai-chips-supercomputer-aws-annapurna-trainium-a943be71
1•bookofjoe•41m ago•1 comments

I Was Wrong: AI Won't Overtake Software Engineering

https://timkellogg.me/blog/2025/05/10/ai-code-updated
1•tkellogg•44m ago•0 comments

Huginn is a system for building agents that perform automated tasks online

https://github.com/huginn/huginn
1•Bluestein•46m ago•0 comments

A constructive proof that P ≠ NP using circuit-resistant encodings

https://doi.org/10.13140/RG.2.2.14071.74408
2•vicentesteve•58m ago•1 comments

Mexico sues Google over 'Gulf of America' name change

https://www.bbc.com/news/articles/c5yk5nj7p7ko
4•doener•59m ago•2 comments

Show HN: I built a system to make ChatGPT brutally honest with you

https://www.honestprompts.com/
1•moobuilds•1h ago•0 comments

Zig, the Ideal C Replacement Or?

http://bitshifters.cc/2025/05/04/zig.html
3•ksec•1h ago•1 comments

Las Médulas

https://en.wikipedia.org/wiki/Las_Médulas
1•perihelions•1h ago•0 comments

'It's an illogical job': Why driving a train isn't as cushy as it might seem

https://www.theguardian.com/business/2025/may/11/its-an-illogical-job-why-driving-a-train-isnt-as-cushy-as-it-might-seem
2•Bluestein•1h ago•0 comments