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Epigenetic heterogeneity in breast tumours informs diagnosis and prognosis

https://www.nature.com/articles/s41586-026-11230-y
1•wslh•1m ago•0 comments

Reddit broken on desktop as full-screen mobile app prompt takes over page

https://piunikaweb.com/2026/11/11/reddit-broken-desktop-get-the-app-popup-freeze/
2•DeepLogin•7m ago•0 comments

ApoB-100 – 50 years unsolved, measured disordered, folded to order

https://github.com/alozano978-spec/the-apob-protein
1•forged-on-chain•8m ago•0 comments

Wiki.js 3.0 Release

https://js.wiki/blog/2026-wiki-js-3-release/
1•ethanbezz•12m ago•0 comments

Lego marketplace BrickLink offline after 'unusual activity' detected

https://www.bbc.com/news/articles/c6rmgw8zynr4o
2•mbrd•14m ago•0 comments

Jobdork – job leads from employers' career sites, ranked by your resume

https://github.com/jessn-dev/jobDork
1•jbn-dev•15m ago•0 comments

Coding is dead, long live Coding

https://twitter.com/i/article/2103571281014861957
1•iloveyoutwo•15m ago•1 comments

U.S. Partner

https://join.slack.com/t/percys-hq/shared_invite/zt-4gjahdd78-Rg5Vayh_BDP~ReWa7cZHwg
1•wawrzaszekerwin•16m ago•0 comments

What gives you the chills? AI can engineer it

https://medium.com/@joshbocanegra/how-to-engineer-goosebumps-e18935bcb1d2
1•jbai•19m ago•0 comments

San Francisco youth culture died at a peptide party in Fisherman's Wharf

https://www.sfgate.com/local/article/sf-culture-fishermans-wharf-22523601.php
3•toomanyrichies•20m ago•0 comments

Yes, you should panic about AI

https://rutgerbregman.substack.com/p/yes-you-should-panic-about-ai
2•haizhung•20m ago•0 comments

Lessons from 59 Linux Kernel Bug Reports

https://www.microsoft.com/en-us/security/blog/2026/11/11/lessons-from-59-linux-kernel-bug-reports/
1•wondersky•21m ago•0 comments

Keeping names, emails and phone numbers out of LLM prompts with a local proxy

https://github.com/rmpmrepo1278/swapback
1•rohitmishra1278•22m ago•0 comments

Porting my Electron app to Rust: 675 MB to 91 MB

https://sayjot.xyz/blog/rust-port
1•mohakbajaj•29m ago•0 comments

Show HN: Tsfm-pg: Run Chronos-2/Timestral forecasts inside Postgres with SQL

https://github.com/barddoo/tsfm-pg
1•pseudocharles•31m ago•1 comments

Labdoo is a social network providing schools with computers

https://labdoo.org
1•mooreds•33m ago•0 comments

Apple MacBook Pro 14 Proled XDR Review

https://www.notebookcheck.net/Amazing-OLED-panel-Apple-MacBook-Pro-14-PROLED-XDR-Review.1438048.0...
2•zathan•39m ago•0 comments

Ask HN: Skills expected for junior to mid-level DevOps/infra roles in the US?

1•GR_08•40m ago•0 comments

Humanoid robot startup backed by Eric Trump in talks with Israel's military

https://www.ft.com/content/8117b912-ebc7-46b2-90cd-a1ec32e12c5a
2•petethomas•40m ago•1 comments

History of Password Cracking

https://www.netmux.com/blog/history-of-password-cracking
3•netmux•43m ago•0 comments

Show HN: I built a AI acne coach that helps find root cause of your acne

https://acneally.vercel.app
2•trinh312•43m ago•0 comments

The $637B Ledger

https://the-compound-loop.beehiiv.com/p/the-637-billion-ledger
1•bossness00•43m ago•0 comments

Show HN: W-ISA – An instruction set for programming LLM weights

https://github.com/eax/w-isa
2•eaxitect•45m ago•0 comments

Huawei says it's made a 100 percent Chinese PC

https://www.theregister.com/systems/2026/11/09/huawei-says-its-made-a-100-percent-chinese-pc/5308335
2•yogthos•45m ago•1 comments

Nvidia reportedly preparing to fire CEO Jensen Huang, amid of second affair

https://www.rnz.co.nz/news/business/2553062/nvidia-reportedly-preparing-to-fire-ceo-jensen-huang-...
4•billybuckwheat•46m ago•2 comments

Shruti Rajagopalan: The Political Economy of Gulliver's Travels

https://www.commonreader.co.uk/p/shruti-rajagopalan-the-political
2•paulpauper•48m ago•0 comments

Tyler Cowen: Jensen Huang's Is Out. Who's Next?

https://www.thefp.com/p/tyler-cowen-jensen-huangs-secret-is-out
1•paulpauper•48m ago•0 comments

Passing of Richard A. Posner, Senior Lecturer, Law and Economics Pioneer

https://www.law.uchicago.edu/news/senior-lecturer-richard-posner-law-and-economics-pioneer-and-fo...
4•paulpauper•49m ago•0 comments

Get ready for fewer Opus em-dashes

https://micjm.com/blog/get-ready-for-fewer-opus-5.5-em-dashes/
2•seizethecheese•51m ago•1 comments

Hands on with Home Assistant's new 'smart home multi-tool'

https://www.theverge.com/tech/1031601/home-assistant-connect-aux-2-hands-on
2•qzervaas•52m ago•0 comments
Open in hackernews

Show HN: Raw Binary Program Analysis Tool

https://github.com/nstarke/BaseAddressDiscoverererer
2•bootbloopers•1y ago
I built a tool for analyzing raw binary programs (programs without an ELF, PE, Mach-O header) to determine the file offset that the program begins at and the load address the program is mapped into memory at. The tool can also do find the instruction set architecture for common platforms. I put a lot of effort into making it as easy as possible to run, and there is a quick start script that takes a single argument: the absolute file path to a raw binary program file.