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Show HN: Pyrig – One command to set up a production-ready Python project

https://github.com/Winipedia/pyrig
1•Winipedia•57s ago•0 comments

Fast Response or Silence: Conversation Persistence in an AI-Agent Social Network [pdf]

https://github.com/AysajanE/moltbook-persistence/blob/main/paper/main.pdf
1•EagleEdge•1m ago•0 comments

C and C++ dependencies: don't dream it, be it

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Show HN: Vbuckets – Infinite virtual S3 buckets

https://github.com/danthegoodman1/vbuckets
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Open Molten Claw: Post-Eval as a Service

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New York Budget Bill Mandates File Scans for 3D Printers

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The End of Software as a Business?

https://www.thatwastheweek.com/p/ai-is-growing-up-its-ceos-arent
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Exploring 1,400 reusable skills for AI coding tools

https://ai-devkit.com/skills/
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Show HN: A unique twist on Tetris and block puzzle

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The logs I never read

https://pydantic.dev/articles/the-logs-i-never-read
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How to use AI with expressive writing without generating AI slop

https://idratherbewriting.com/blog/bakhtin-collapse-ai-expressive-writing
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Show HN: LinkScope – Real-Time UART Analyzer Using ESP32-S3 and PC GUI

https://github.com/choihimchan/linkscope-bpu-uart-analyzer
1•octablock•10m ago•0 comments

Cppsp v1.4.5–custom pattern-driven, nested, namespace-scoped templates

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1•user19870•12m ago•1 comments

The next frontier in weight-loss drugs: one-time gene therapy

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1•bookofjoe•15m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
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Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
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Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
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Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•22m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•23m ago•0 comments

Hello

2•otrebladih•24m ago•1 comments

FSD helped save my father's life during a heart attack

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Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
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Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

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Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

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Transcribe your aunts post cards with Gemini 3 Pro

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.72% Variance Lance

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ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
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Encrypt It

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NextMatch – 5-minute video speed dating to reduce ghosting

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Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•42m ago•0 comments
Open in hackernews

The Battle to Bottle Palm Wine (2021)

https://www.atlasobscura.com/articles/palm-wine-in-united-states
17•prmph•9mo ago

Comments

jollyllama•8mo ago
https://en.wikipedia.org/wiki/Nipah_virus_infection#Preventi...
xnx•8mo ago
> 50% to 75% of those infected die

Whoa

howard941•8mo ago
What is it about bats that makes them vectors for so many maladies? EDITED to remove spurious ref to rodents
neaden•8mo ago
A big thing is that Bats have a really weird metabolism, during their day it can dip down to 50 Fahrenheit and then go up to 104 F at night when they are active. This can mean they end up carrying a lot of diseases but not dying/showing symptoms of them. They also have very strong DNA repair compared to other mammals. Then in addition many bats are very social and sleep in big groups, which means the disease can spread throughout the bat population.

Edit: Finally and relevantly they can come in close contact with people by coming into our homes, or people going into theirs. This can let the disease cross over.

thaumasiotes•8mo ago
> Bats have a really weird metabolism, during their day it can dip down to 50 Fahrenheit and then go up to 104 F at night when they are active. This can mean they end up carrying a lot of diseases but not dying/showing symptoms of them.

What is the connection between these two ideas?

neaden•8mo ago
Most organisms, including pathogens, have a relatively narrow temperature range they operate in. Hence why we get fevers in order to fight them off. Bats spend most of the time too cold, then get up to the equivalent of a high grade fever for an extended time. Here's a paper on the subject https://pmc.ncbi.nlm.nih.gov/articles/PMC4012789/
thaumasiotes•8mo ago
That covers the first sentence. How does it connect to the second one? So far, you've described how you would expect bats to carry very few diseases, because diseases that found themselves inside a bat would be killed by the temperature fluctuations. It does not appear to follow that bats should be hosting a lot of diseases at any given time.
jollyllama•8mo ago
You've made an interesting counterargument that I've never come across before. I'm purely speculating here, but maybe the diseases in question (rabies, nipah) are otherwise so deadly that they'd normally just kill the host, but in bats, they linger on. All that to say, that bats aren't necessarily hosting more diseases relative to other animals, but they harbor diseases at the more lethal end of the virulence to transmission tradeoff spectrum.
thaumasiotes•8mo ago
What do you mean, counterargument? A "counterargument" can only exist relative to an argument. So far there hasn't been an argument. To recap:

1. "A big reason bats carry a lot of diseases is that they have large temperature fluctuations."

2. "How does the one lead to the other?"

3. "Diseases can't tolerate temperature fluctuations."

That's gibberish, not an argument. Combining two random (or in this case, contradictory) sentences doesn't make an argument.

system7rocks•8mo ago
I am very intrigued as local, culturally specific wines/beers/fermentation speak so much to our creativity and community as human beings.

But thanks for the heads up about Nipah Virus! Wow!

decimalenough•8mo ago
Not mentioned is one more part of the battle: toddy is considered a low-class drink for rowdy workers, and tightly regulated accordingly. This guy has been battling Singaporean bureaucracy for six years now just to be allowed to import it from neighboring Malaysia:

https://www.ricemedia.co/one-mans-quest-to-revive-toddy-the-...

Our_Benefactors•8mo ago
What’s the average ABV of palm wine?
a_t48•8mo ago
Ever since seeing https://www.youtube.com/watch?v=6skjbVDVEg4 my wife has been trying to find a way of importing it to make the dish herself
dluan•8mo ago
This story is from 2021 so I wonder how those startups are faring now. For a while molecular alcohol was the hot thing, with startups like Endless West raising a lot of VC to try and shortcut aging.
comrade1234•8mo ago
I used to travel to India a lot and would have this when staying with friends in Hyderabad, flies and all. My friend would send one of his servants out in the morning to buy it for us. The way he explained it - someone would climb the palm tree in the evening, make cuts in a place where the liquid would leak out and pool, then there would be fermentation overnight (bacterial, not yeast), and then they collect it on the morning.

It reminded me of a drink here in Switzerland made during grape harvest and also bacterial fermentation. Also sour cider in the babe region but that’s much more sophisticated.

This palm juice alcohol is very primitive and probably something monkeys drank.

comrade1234•8mo ago
Basque region, not bape region.
toddydrinker•8mo ago
> staying with friends in Hyderabad, flies and all.

Hmm... flies and all?

> send one of his servants out in the morning to buy it for us.

Hmmm..... one. servants?

> This palm juice alcohol is very primitive and probably something monkeys drank.

Hmm... primitive? monkeys?

Sorry, but I got an uncomfortable feeling from reading your comment. I think my insula cortex activated upon detecting chromatocrat type verbiage.

MentatOnMelange•8mo ago
Not the OP, and my initial reaction was very similar. I'm giving the benefit of the doubt though and assume he meant monkeys in India will drink the naturally-occuring fermentation similar to how moose/elk in Scandinavia will get drunk on overly ripe fruit.

https://enviroliteracy.org/animals/can-elk-get-drunk/

Probably could have been a better choice of example than a monkey but if you spend a lot of time in India, the "we normally see these in a zoo!" novelty probably wears off quickly and its no different than dealing with deer in north america.

prmph•8mo ago
What makes an alcoholic drink "primitive"?