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Glia-associated amyloid β oligomer subtype and rescue from reactive astrogliosis

https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.70968
1•bookofjoe•1m ago•0 comments

I built a retro mini PC which uses game cartridges [video]

http://youtube.com/watch?v=iJbJDowBfi4
1•abeisgreat•3m ago•1 comments

Genesis Open Source Embodied AGI Simulation, Rust (Mamba-3, Not Transformers)

1•RGBra•5m ago•0 comments

Reddit comment led police to identify Brown University shooter

https://9to5mac.com/2025/12/22/reddit-comment-led-police-to-identify-brown-university-shooter/
1•akyuu•6m ago•0 comments

Free to Post, Impossible to Hide: The End of Anonymous Marketplaces

https://medium.com/@lea.leumassart/free-to-post-impossible-to-hide-the-end-of-anonymous-marketpla...
1•pbacdf•7m ago•0 comments

Meilisearch: Make the S3-streaming snapshots an Enterprise Edition feature

https://github.com/meilisearch/meilisearch/pull/6057
1•iruoy•9m ago•0 comments

How AI Collapses and Rebuilds Marketplace Moats

https://www.caseyaccidental.com/p/when-agents-attack-how-ai-collapses
1•gmays•10m ago•0 comments

Banana is Generating Antimatter, And I Detected It [video]

https://www.youtube.com/watch?v=ZOTsDmeM0No
2•jmward01•11m ago•1 comments

Show HN: Cardly – a tiny card-first app to capture people's Gift Cards

https://www.cardlyai.app/
1•Pastaza•11m ago•1 comments

Show HN: Making SVG Sparkline Component with an Agent to Graph Token Usage

https://bsky.app/profile/verdverm.com/post/3makhu3nbm22n
1•verdverm•11m ago•0 comments

Show HN: Find games with few -but positive- reviews based on games that you like

https://www.notsoaaa.com/
1•AmbroseBierce•14m ago•0 comments

Show HN: LLVM-jutsu: Anti-LLM obfuscation pass

https://github.com/thebabush/llvm-jutsu
1•babush•15m ago•0 comments

Welcome to Kenya's Great Carbon Valley a bold new gamble to fight climate change

https://www.technologyreview.com/2025/12/22/1130153/geothermal-energy-carbon-capture-kenya-climat...
1•rbanffy•15m ago•0 comments

How the Cybertruck's design may have trapped crash survivors in flames

https://www.washingtonpost.com/technology/interactive/2025/cybertruck-crash-design-lawsuit/
2•Jtsummers•15m ago•0 comments

Paperbacks and TikTok

https://calnewport.com/on-paperbacks-and-tiktok/
1•zdw•16m ago•0 comments

Lua 5.5 Released

https://www.lua.org/manual/5.5/readme.html#changes
2•todsacerdoti•16m ago•1 comments

Best way to annotate large parquet LLM logs without full rewrites?

1•platypii•19m ago•0 comments

The Program 2025 annual review: How much money does an audio drama podcast make?

https://programaudioseries.com/the-program-results-7/
2•I-M-S•19m ago•1 comments

ChatGPT Is a Search Engine

https://queryburst.com/blog/how-chatgpt-works/
1•AznHisoka•20m ago•0 comments

Power outage paralyzes Waymo robotaxis when traffic lights go out

https://arstechnica.com/cars/2025/12/power-outage-paralyzes-waymo-robotaxis-when-traffic-lights-g...
2•chirau•21m ago•1 comments

Reducing contrails reduces CO2 effect of air travel 73%, adds only 0.08% to cost [video]

https://www.youtube.com/watch?v=QoOVqQ5sa08
1•CGMthrowaway•25m ago•0 comments

Algorithmic Personalization Causes Inaccurate Generalization and Overconfidence

https://psycnet.apa.org/fulltext/2026-31272-001.html
1•PaulHoule•25m ago•0 comments

Inquiry ongoing after UK government hacked, says minister

https://www.bbc.co.uk/news/articles/cj4qpwprw9vo
1•GaryBluto•25m ago•0 comments

Older Americans Quit Weight-Loss Drugs in Droves

https://www.nytimes.com/2025/12/21/health/older-people-glp1-weight.html
3•bookofjoe•26m ago•1 comments

Samsung Biologics to buy US drug production facility from GSK for $280M

https://www.reuters.com/business/healthcare-pharmaceuticals/samsung-biologics-buy-us-drug-product...
2•randycupertino•27m ago•0 comments

The Fisherman and the Businessman

https://kevquirk.com/blog/the-fisherman-and-the-businessman/
1•0x54MUR41•27m ago•0 comments

A zero-dependency approach to archival, interactive research

https://tjid3.org/tech
1•TimothyMJones•27m ago•1 comments

MacSync Stealer variant finds a way to bypass Apple malware protections

https://9to5mac.com/2025/12/22/macsync-stealer-variant-finds-a-way-to-bypass-apple-malware-protec...
1•zdw•28m ago•0 comments

Intel x86 considered harmful [pdf]

https://blog.invisiblethings.org/papers/2015/x86_harmful.pdf
2•throwoutway•28m ago•0 comments

National Portrait Gallery Buys Rare Photographs of Ada Lovelace for the UK

https://www.ianvisits.co.uk/articles/national-portrait-gallery-saves-rare-photographs-of-ada-love...
3•ianvisits•28m ago•1 comments
Open in hackernews

Xkcd's "Is It Worth the Time?" Considered Harmful

https://will-keleher.com/posts/its-not-worth-the-time-yet.html
27•gcmeplz•7mo ago

Comments

jjk166•7mo ago
XKCD's comic is a very simple graphic that tells you whether your automation efforts will reduce the total amount of time for a task.

If your goal is not to reduce time spent, why would you be looking at a chart to determine how much time you're reducing?

Learning is a very good use of time. Choosing to spend extra time to automate something for the sake of learning is a perfectly rational decision. But it's never harmful to know what your choice is costing you. If you wouldn't be willing to automate something in the full knowledge that it's going to take longer than just doing it manually, then the comic is succeeding in stopping you from making a choice you wouldn't want to make.

arcfour•7mo ago
My boss would probably prefer—thinking short-term—that I work by that chart. I would prefer to learn something new, and it usually pays off in the long-term, possibly years from now in unexpected and unforeseeable ways.
banku_brougham•7mo ago
Yup if I followed team/management guidance I would be nowhere.
jjk166•7mo ago
"This may help in unexpected and unforeseeable ways" doesn't sound like the most convincing argument for taking time from your job to learn a new skill.

All the same, you are choosing to learn something new, not to automate something to save time. Learning something new by automating a task which doesn't justify automation is no different from say reading a book or doing coding exercises in the same time - it's potentially a good use of your time, it just doesn't relate to the xkcd chart at all.

patrakov•7mo ago
Key sentence from the article:

> Automating the easy things is how you build the skills, mindset, and muscle-memory to automate the hard things.

hicksyfern•7mo ago
The counter to that is that going and looking at the call sites to that function would have given the author a better understanding of what those call sites were, why they called the function, etc, thus learning more about the codebase.
abc-1•7mo ago
The goal to automate is to reduce suffering. Full stop. It’s not to “save time”. STEM types like to pretend they’re stoic cold calculating robots and everything is objective and they don’t mind doing some repetitive 5 minute task every day, because they saw some xkcd comic about efficiency. Maybe they pretend they don’t mind simply so they can smugly post the xkcd comic every time someone new asks why they’re suffering through some repetitive slog.
banku_brougham•7mo ago
exactly. work can be fun and there is so much to learn.
try_the_bass•7mo ago
Harmful? No. Good rule of thumb? Yeah. Like any rule of thumb, if followed dogmatically, it loses the nuance that makes it a good "rule of thumb".
add-sub-mul-div•7mo ago
Right. Almost nothing should be followed dogmatically, but a major theme of this site is to act like all advice was meant to be taken as gospel and then counter it with mundane exceptions.
karmakaze•7mo ago
> ...updating the order of arguments to a function [...] was only in about 10 spots, so it would have only taken a minute to search and fix manually, but instead I spent an hour automating the fix using sed and xargs. And I think that was the right choice.

Spending an hour to learn and use sed/xargs is good use of time. Bringing in the xkcd formula has nothing to do with that. It could/should have been done as a one-off whether manually or scripted. Automation doesn't make sense unless you plan to keep putting me function arguments in an undesired order.

I would have put in time sooner to use a static typed language the can reliably reactor in the IDE with a click.

dontreact•7mo ago
The flip side of this is that for some tasks (especially in ml/ai), doing it manually at least a few times gives you a sense of what is correct and a better sense of detail.

For example, spending the time to label a few examples yourself instead of just blindly sending it out to labeling.

(Not always the case, but another thing to keep in mind besides total time saved and value of learning)

more_corn•7mo ago
“Considered harmful” is considered harmful
V__•7mo ago
> Automating the easy things is how you build the skills, mindset, and muscle-memory to automate the hard things.

I agree with the statement, yet I think it misses the point. Hyperbole: Pressing play on a mp3 robs you of the experience of learning to play all instruments yourself. They key question is whether automating is a task one wants to improve in at all.

phendrenad2•7mo ago
I agree. The author spent an hour of trying to use 'sed', and the next time, they thought better and used Python! That's a valuable lesson right there! ;)
al_borland•7mo ago
There is also the situation where if it doesn’t get automated, it won’t be done at all. Some things are just too annoying to manually do, especially if it would be nice if they were done more than once.

There is also an aspect of repeatability without mistakes. Assuming the code is good, it removes the human error from the equation, which has value.

atoav•7mo ago
This is about tasks you automate to save time, that however isn't the only reason to automate a task.

A big one for me is to ensure consistency of data, intervals, etc.

banku_brougham•7mo ago
Every day you are building the foundation for the rest of your career. When I can I execute tasks as though need to scale and be instrumented with alarms.