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Go 1.22, SQLite, and Next.js: The "Boring" Back End

https://mohammedeabdelaziz.github.io/articles/go-next-pt-2
1•mohammede•2m ago•0 comments

Laibach the Whistleblowers [video]

https://www.youtube.com/watch?v=c6Mx2mxpaCY
1•KnuthIsGod•3m ago•1 comments

I replaced the front page with AI slop and honestly it's an improvement

https://slop-news.pages.dev/slop-news
1•keepamovin•8m ago•1 comments

Economists vs. Technologists on AI

https://ideasindevelopment.substack.com/p/economists-vs-technologists-on-ai
1•econlmics•10m ago•0 comments

Life at the Edge

https://asadk.com/p/edge
1•tosh•16m ago•0 comments

RISC-V Vector Primer

https://github.com/simplex-micro/riscv-vector-primer/blob/main/index.md
2•oxxoxoxooo•19m ago•1 comments

Show HN: Invoxo – Invoicing with automatic EU VAT for cross-border services

2•InvoxoEU•20m ago•0 comments

A Tale of Two Standards, POSIX and Win32 (2005)

https://www.samba.org/samba/news/articles/low_point/tale_two_stds_os2.html
2•goranmoomin•24m ago•0 comments

Ask HN: Is the Downfall of SaaS Started?

3•throwaw12•25m ago•0 comments

Flirt: The Native Backend

https://blog.buenzli.dev/flirt-native-backend/
2•senekor•26m ago•0 comments

OpenAI's Latest Platform Targets Enterprise Customers

https://aibusiness.com/agentic-ai/openai-s-latest-platform-targets-enterprise-customers
1•myk-e•29m ago•0 comments

Goldman Sachs taps Anthropic's Claude to automate accounting, compliance roles

https://www.cnbc.com/2026/02/06/anthropic-goldman-sachs-ai-model-accounting.html
2•myk-e•31m ago•4 comments

Ai.com bought by Crypto.com founder for $70M in biggest-ever website name deal

https://www.ft.com/content/83488628-8dfd-4060-a7b0-71b1bb012785
1•1vuio0pswjnm7•32m ago•1 comments

Big Tech's AI Push Is Costing More Than the Moon Landing

https://www.wsj.com/tech/ai/ai-spending-tech-companies-compared-02b90046
4•1vuio0pswjnm7•34m ago•0 comments

The AI boom is causing shortages everywhere else

https://www.washingtonpost.com/technology/2026/02/07/ai-spending-economy-shortages/
2•1vuio0pswjnm7•36m ago•0 comments

Suno, AI Music, and the Bad Future [video]

https://www.youtube.com/watch?v=U8dcFhF0Dlk
1•askl•38m ago•2 comments

Ask HN: How are researchers using AlphaFold in 2026?

1•jocho12•41m ago•0 comments

Running the "Reflections on Trusting Trust" Compiler

https://spawn-queue.acm.org/doi/10.1145/3786614
1•devooops•46m ago•0 comments

Watermark API – $0.01/image, 10x cheaper than Cloudinary

https://api-production-caa8.up.railway.app/docs
1•lembergs•47m ago•1 comments

Now send your marketing campaigns directly from ChatGPT

https://www.mail-o-mail.com/
1•avallark•51m ago•1 comments

Queueing Theory v2: DORA metrics, queue-of-queues, chi-alpha-beta-sigma notation

https://github.com/joelparkerhenderson/queueing-theory
1•jph•1h ago•0 comments

Show HN: Hibana – choreography-first protocol safety for Rust

https://hibanaworks.dev/
5•o8vm•1h ago•1 comments

Haniri: A live autonomous world where AI agents survive or collapse

https://www.haniri.com
1•donangrey•1h ago•1 comments

GPT-5.3-Codex System Card [pdf]

https://cdn.openai.com/pdf/23eca107-a9b1-4d2c-b156-7deb4fbc697c/GPT-5-3-Codex-System-Card-02.pdf
1•tosh•1h ago•0 comments

Atlas: Manage your database schema as code

https://github.com/ariga/atlas
1•quectophoton•1h ago•0 comments

Geist Pixel

https://vercel.com/blog/introducing-geist-pixel
2•helloplanets•1h ago•0 comments

Show HN: MCP to get latest dependency package and tool versions

https://github.com/MShekow/package-version-check-mcp
1•mshekow•1h ago•0 comments

The better you get at something, the harder it becomes to do

https://seekingtrust.substack.com/p/improving-at-writing-made-me-almost
2•FinnLobsien•1h ago•0 comments

Show HN: WP Float – Archive WordPress blogs to free static hosting

https://wpfloat.netlify.app/
1•zizoulegrande•1h ago•0 comments

Show HN: I Hacked My Family's Meal Planning with an App

https://mealjar.app
1•melvinzammit•1h ago•0 comments
Open in hackernews

SSRIs induce cardiac toxicity through dysfunction of mitochondria and sarcomeres

https://www.nature.com/articles/s42003-025-08168-8
18•XzetaU8•8mo ago

Comments

valec•8mo ago
in fetuses.
Mo3•8mo ago
I had to get off my SSRI because I'm apparently prone to prolonged QT interval and the SSRI could cause sudden cardiac arrest. (I am not a fetus)
washadjeffmad•8mo ago
Before the rest of them arrive, could you also confirm that you are not a mouse?
reify•8mo ago
Upon reading this you may well think that I am some sort of conspiracy theorist.

I am in fact a retired Psychotherapist, in professional practice for over 25 years.

I have seen my fair share of damage to my patients and clients caused by SSRI's.

One of the most dangerous prescribed drugs on the planet.

Its a big con.

chemical imbalance is a myth.

There is no such thing as chemical imbalance, this myth was manufactured by drug companies in the late 1980's to sell SSRI's to the unsuspecting public.

SSRI's create a paradoxical reaction.

meaning that the drug creates the depressive sympsoms experienced by the patient.

Some studies have been published that show that these antidepressants may deteriorate the state of the depression (make it worse) and even cause suicidal ideation or action.

2018 paper https://fse.studenttheses.ub.rug.nl/21028/1/Thesis-Neurobiol...

paradoxical reaction, a guide https://en.wikipedia.org/wiki/Paradoxical_reaction

It has taken over 30 years for drug companies to accept that SSRI's cause sexual disfunction and has finally been included in the DSM5 as PSSD, post ssri sexual disfunction.

In some unpublished phase 1 trials of the drug, more than 50% of healthy volunteers developed severe sexual problems. but they kept it quiet.

Highlighted in the Guardian just last year.

https://www.theguardian.com/society/2024/mar/02/ssri-antidep...

AStonesThrow•8mo ago
When I was 19, my parents sent me to see a therapist. This therapist's office was in the Children's Hospital, and it was already humiliating to walk into that place as a grown man and there is a waiting room with toys and building blocks for me to play with.

Anyway, the therapist gave me a few "pep-talk sessions" which did not seem oriented at all to helping me get better, or discern the root causes of my depression. The therapist proceeded to help me claim disability at work and get back into college. He also referred me to his next-door neighbor, the psychiatrist.

So I go home with my first SSRI prescription and start taking it. My mother soon exclaimed how much better I was acting. I was smiling and full of energy.

And it turns out that whether or not we are ingesting fluoride orally, people do act and feel better when they are seeing a therapist and getting attention. For a time there, I actually felt like people cared about my well-being and there were things being done about it.

Upon my diagnoses, the nurses would often regale me with stories about how the noblest politicians and artists were afflicted with the same things I was. This was cold comfort. They all insisted it was a chemical imbalance, and their own cocktail of chemicals was bound to offset this crazy wrong-headed chemistry that had gotten mixed up in my head (nevermind that most serotonin has nothing to do with the brain, and is mostly in your digestive system?)

Now there were many dark things I didn't know about the fluoride pills they had prescribed me. I suffered several disastrous interactions with alcohol before they told me it's not a good idea to drink. I had those "brain zap" withdrawal symptoms when I hadn't taken enough.

Thankfully, I did not experience the suicidal or homicidal tendencies which can come with taking SSRIs. Yes, homicide is a common reaction to being drugged. Before SSRIs, Charles Whitman loved his Dexedrine, and packed a goodly supply as he scaled the tower in Texas. The Columbine Kids, very intelligent boys, had all been referred to BH care and were all being medicated with SSRIs and other drugs at the time of their untimely deaths and egregious actions.

dttze•8mo ago
Psychotherapy is the con imo. Ssris can be life savers for those with anxiety based disorders.
devwastaken•8mo ago
SSRI’s would be illegal if they werent so profitable. modern society creates the environment where humans are removed from nature.