When I think risk of heart attack, I think of genetics first. Heart attacks seem fairly unlikely in my family. There's not even a rumor of an instance.

Contrasting that is a friend who's family were cursed with a precondition. The men died of heart attacks before their ~45th birthday. My friend dropped dead waiting to pay his restaurant bill with two paramedics standing in line behind him.

I met his younger brother at the funeral. He was in his early 40s and was the last living male over 40, anywhere in his tree.