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Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•43s ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•1m ago•1 comments

NotebookLM: The AI that only learns from you

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Show HN: An open-source starter kit for developing with Postgres and ClickHouse

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Game Boy Advance d-pad capacitor measurements

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South Korean crypto firm accidentally sends $44B in bitcoins to users

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Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
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Google in Your Terminal

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Shannon: Claude Code for Pen Testing: #1 on Github today

https://github.com/KeygraphHQ/shannon
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Anthropic: Latest Claude model finds more than 500 vulnerabilities

https://www.scworld.com/news/anthropic-latest-claude-model-finds-more-than-500-vulnerabilities
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Brooklyn cemetery plans human composting option, stirring interest and debate

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Why the 'Strivers' Are Right

https://greyenlightenment.com/2026/02/03/the-strivers-were-right-all-along/
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Brain Dumps as a Literary Form

https://davegriffith.substack.com/p/brain-dumps-as-a-literary-form
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Agentic Coding and the Problem of Oracles

https://epkconsulting.substack.com/p/agentic-coding-and-the-problem-of
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Malicious packages for dYdX cryptocurrency exchange empties user wallets

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1•Bender•14m ago•0 comments

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https://github.com/pheonix-delta/axiom-voice-agent
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Penisgate erupts at Olympics; scandal exposes risks of bulking your bulge

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4•Bender•15m ago•0 comments

Arcan Explained: A browser for different webs

https://arcan-fe.com/2026/01/26/arcan-explained-a-browser-for-different-webs/
1•fanf2•17m ago•0 comments

What did we learn from the AI Village in 2025?

https://theaidigest.org/village/blog/what-we-learned-2025
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An open replacement for the IBM 3174 Establishment Controller

https://github.com/lowobservable/oec
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The P in PGP isn't for pain: encrypting emails in the browser

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Show HN: Mirror Parliament where users vote on top of politicians and draft laws

https://github.com/fokdelafons/lustra
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Ask HN: Opus 4.6 ignoring instructions, how to use 4.5 in Claude Code instead?

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https://nolanlawson.com/2026/02/07/we-mourn-our-craft/
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Jim Fan calls pixels the ultimate motor controller

https://robotsandstartups.substack.com/p/humanoids-platform-urdf-kitchen-nvidias
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Exploring a Modern SMTPE 2110 Broadcast Truck with My Dad

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The Field Guide to Design Futures

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The Other Leverage in Software and AI

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1•gmays•33m ago•0 comments
Open in hackernews

Ask HN: Moving to London from California

12•siamese_puff•8mo ago
I’m moving from a smaller beach town in California to London in a month as an American. Any tips?

30, no kids and a wife. Felt like life was short, so we found jobs and bought a plane ticket.

Comments

david927•8mo ago
You'll love it. It will change your life in an amazing way.

Tips? Nothing concrete. Be open. Everything will change; let it. What you thought is true and indisputable will be called into question; let it. Find new truths. Bruce Lee said, "Be water." Be water. Allow it to change you and it will, permanently, in the best way possible.

When I was 26, I moved from California to Europe and never looked back. Easily one of the best decisions of my life. Have fun. You won't regret it.

Oh and when they ask you, "Who do you support?" (and they will!) it means which football (soccer) team do you back, and the answer is Liverpool.

P.S. If you have any concrete questions, my email is in my profile.

spacedcowboy•8mo ago
> it means which football (soccer) team do you back, and the answer is Liverpool.

This is the way.

helij•8mo ago
I never understood and would like to know more on why people from London or other areas that are not Liverpool and have no connections to Liverpool whatsoever cheer for Liverpool team. I'm kind of local patriot and always cheer for my local club.
workfromspace•8mo ago
Because with Liverpool you will never walk alone ;)
spacedcowboy•8mo ago
Um, I am from Liverpool. I grew up on Springbank Rd, L4, about spitting distance from Anfield.
sillyfluke•8mo ago
Interesting that you moved from California but do not comment about the London sun at all, though to be fair, you said you yourself moved to Europe and not the UK.

A friend from SoCal who moved to London for a few years couldn't really handle sky getting dark around 3-4 in the afternoon in the winter, and she would say it was almost impossible for her not to get depressed during those times. So just something to be prepared for.

On the bright side though, London, as with many German cities, has short cheap direct flights to many sun bleached cities and beach destinations in Europe so I would suggest making ample use of them if you can. Being in the US afterwards, one realizes there is no location in the mainland US that can compete with the Mediterranean with respect to actually being an inviting body of water to swim in (non mainland Hawaii is obviously an exception).

And May and June in London itself I often find especially beautiful as well.

DamonHD•8mo ago
Whereabouts in London? I am at the south-western edge.

Make use of the huge amounts of green space that London has.

Make use of the nightlife in London.

Make use of the huge number of in-person events in London.

I am contactable via my profile if you'd like a more detailed discussion, and/or to meet for beer, coffee, etc.

colesantiago•8mo ago
Any reason why you want to swap sunshine of California for the grey skies of London? :)

Jokes aside, but just curious what is bad about California that makes you want to go to London?

siamese_puff•8mo ago
Life is short and it seemed fun
ljsocal•8mo ago
Take a day-long walking tour with Fabian. He’s a German expat who is a city plannner in london. Besides being a super-nice guy, his tour offers a view of some of london’s most interesting neighborhoods. Not a tourist’s view. Buy him a beer and tell him Cal sent you. https://www.airbnb.com/slink/IH7SGUyq
thorin•8mo ago
Good luck!

If you like walking try and walk around the centre as much as possible (without using phone mapping ideally), you'll realise it's quite small really and get to know the place. Take some time to experience the history, art galleries, theatre etc I wish I'd done more of that now I live in the provinces.

Take time to see different parts of the UK, although I loved living in London for 2 years and visit a lot I way prefer other parts of the UK and now a lot of people live remotely it's practical to live in the midlands for example and go there for work once a week maybe.

Take regular trips to Europe by plane, train or car. It's cheap and doable for a weekend. There is a lot of variety between countries/cities which I think you'd really appreciate.

random_moonwalk•8mo ago
'you'll realise it's quite small really and get to know the place.'

I've been here for ~10 years and feel like I'm familiar with a fairly narrow slice of it (mostly north/north east a little bit). A good mental model imo is to see it as a collection of smaller towns, each with distinct urban centres, that have grown into each other. This makes it endlessly interesting to me and I feel like I'm unlocking new parts of it all the time.

coolcase•8mo ago
Cambridge is worth a visit it's fairly close by train.
speedylight•8mo ago
Can anyone tell me what London is like (from someone who lives/lived there)? Just overview of the life there, people, job market, etc.
pyb•8mo ago
The best things to see in the area are outside London: Cambridge/Oxford, the Chilterns...

Places to live if you have a comfortable budget : Clapham is popular with young professionals. Hackney is popular with hipsters. Hampstead if you want to live somewhere nice.

Gustomaximus•8mo ago
Unless it really doesn't suit your commute, pay more to be central. This will help you see the city + be social. It can be really difficult if you are one side of the city and your friends end up being the other side as you can have an hour travel to see people type deal.

With location, proximity to a station & what train line matters - you'll likely use the underground a bunch so consider your commute for this closely.

Take one of those bus tours. I did only after living there for years as 'that's for tourists' but its really worth it and gives a good city perspective.

Do lots of travel to Europe from London. So much is on your doorstep with cheap flights if flexible on where you go. Take advantage of this especially if kids are on the horizon.

If you dont already, learn to like beer and pubs. There's something better about British pubs and pub culture. Also it usually well priced reasonable quality meals.

Speaking of pubs, anything crowded in the city will have pickpockets so watch you phone/bag closely or it wont be there.

Its quite common to rent flats furnished, this is likely a good option for you to start. Also what I did as I had no rental history there is offer to pay 6-months up front (and requested a discount for that) to show there financial risk was reduced.

Its an awesome city - I personally enjoyed immensely. I noticed people tended to be there 6-month or 6-years - it was kind of love or hate though, with the majority loving.

Oh and go to Shakespeare's globe theatre for me will you. I walked past that place for 2 years thinking I'll line that one up sometime and never did!