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Open Molten Claw: Post-Eval as a Service

https://idiallo.com/blog/open-molten-claw
1•watchful_moose•33s ago•0 comments

New York Budget Bill Mandates File Scans for 3D Printers

https://reclaimthenet.org/new-york-3d-printer-law-mandates-firearm-file-blocking
1•bilsbie•1m ago•0 comments

The End of Software as a Business?

https://www.thatwastheweek.com/p/ai-is-growing-up-its-ceos-arent
1•kteare•2m ago•0 comments

Exploring 1,400 reusable skills for AI coding tools

https://ai-devkit.com/skills/
1•hoangnnguyen•3m ago•0 comments

Show HN: A unique twist on Tetris and block puzzle

https://playdropstack.com/
1•lastodyssey•6m ago•0 comments

The logs I never read

https://pydantic.dev/articles/the-logs-i-never-read
1•nojito•7m ago•0 comments

How to use AI with expressive writing without generating AI slop

https://idratherbewriting.com/blog/bakhtin-collapse-ai-expressive-writing
1•cnunciato•8m ago•0 comments

Show HN: LinkScope – Real-Time UART Analyzer Using ESP32-S3 and PC GUI

https://github.com/choihimchan/linkscope-bpu-uart-analyzer
1•octablock•9m ago•0 comments

Cppsp v1.4.5–custom pattern-driven, nested, namespace-scoped templates

https://github.com/user19870/cppsp
1•user19870•10m ago•1 comments

The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•13m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•16m ago•3 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
2•sara_builds•16m ago•1 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•17m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•21m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•21m ago•0 comments

Hello

2•otrebladih•23m ago•1 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•25m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•27m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•29m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•31m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•35m ago•0 comments

.72% Variance Lance

1•mav5431•36m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•38m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•38m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•39m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•40m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•41m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•41m ago•2 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•42m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•42m ago•0 comments
Open in hackernews

'Turbocharged' Mitochondria Power Birds' Epic Migratory Journeys

https://www.quantamagazine.org/turbocharged-mitochondria-power-birds-epic-migratory-journeys-20250519/
78•pseudolus•8mo ago

Comments

coolcase•8mo ago
Wouldn't mind some bird mitochondria!
b800h•8mo ago
Seriously, what would happen if we swapped out human mitochondria from a zygote for bird mitochondria?
jyounker•8mo ago
I don't think you'd get the same sort of effects, because a huge part of the mitochondrial regulation and function is carried out by genes and gene products from outside the mitochondria.

It would be an interesting experiment though. I'd expect that they might not live, or that the cell would function sub-optimally, but who knows, maybe the cellular machinery is highly conserved.

dejj•8mo ago
Yes. Afaik from Nick Lane’s “Oxygen” the Cytochrome Oxidase made from the mitochondrial DNA have to match the Cytochrome C made from nuclear DNA. Even slight mismatch seems to lower mitochondrial performance and is a problem why heteroplasmy (mixing of mitochondria from father and mother) seems to be selected-out.
treyd•8mo ago
Well what if you also swapped out those genes?
dejj•8mo ago
If your mitochondria have bird DNA and your nucleus has bird DNA, then you’re a bird.

There’s an easier way. A single nucleotide polymorphism (SNP) that only and rarely is observed in Japanese can extend human lifespan greatly. Flip a single base pair. This seems the most promising first step for genetically engineering humans.

dghughes•8mo ago
You'd get Kids in the Hall Chicken Lady.
mckirk•8mo ago
And some whale blood!
ljf•8mo ago
Previously posted: https://news.ycombinator.com/item?id=44051652 (1 day ago, 78 comments)
rbanffy•8mo ago
Can the entries be merged?
EGreg•8mo ago
Can they? Yes. Should they? No.
rbanffy•8mo ago
Why have two separate discussions on the same topic a day apart?
gherkinnn•8mo ago
No layman's discussion about mitochondria is complete without the In Our Time episode on just that:

https://www.bbc.co.uk/programmes/m001md34

It is one of my favourites.

londons_explore•8mo ago
What is the typical lifespan of ATP within a cell?

Are we talking milliseconds or minutes?

pfdietz•8mo ago
According to the wikipedia page on ATP, the average ATP concentration in eukaryotic cells is 1 to 10 micromols per gram.

According to https://bionumbers.hms.harvard.edu/bionumber.aspx?s=n&v=2&id... a single mammalian cell has a mass of 3 to 4 nanograms.

Google AI tells me the average rate of ATP formation in a mammalian cell is around 10 million molecules per second.

The ratio here ranges from 3 to 40 minutes.

I imagine it varies greatly depending on cell type.

eitally•8mo ago
From an exercise physiology point of view, it's generally accepted that ATP-CP powered motility is possible for only about 10 seconds (that is to say, you only store enough ATP for about 10 seconds of high intensity work -- sprinting, maximal weight lifting, etc). After that, other energy systems become dominant ... both of which create ATP but depend on either glycolysis (anaerobic) or oxidative phosphorylation (aerobic) for the process/conversion.
ck2•8mo ago
vaguely related there is a fantastic new PBS Space Time this week which suggests the "no alien life" fermi paradox may be related to how our mitochondria evolved by a series of fortunate accidents which may not be reproducible elsewhere

https://www.pbs.org/video/is-there-a-simple-solution-to-the-...

( https://www.youtube.com/watch?v=abvzkSJEhKk )