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RFCs vs. READMEs: The Evolution of Protocols

https://h3manth.com/scribe/rfcs-vs-readmes/
1•init0•4m ago•1 comments

Kanchipuram Saris and Thinking Machines

https://altermag.com/articles/kanchipuram-saris-and-thinking-machines
1•trojanalert•4m ago•0 comments

Chinese chemical supplier causes global baby formula recall

https://www.reuters.com/business/healthcare-pharmaceuticals/nestle-widens-french-infant-formula-r...
1•fkdk•7m ago•0 comments

I've used AI to write 100% of my code for a year as an engineer

https://old.reddit.com/r/ClaudeCode/comments/1qxvobt/ive_used_ai_to_write_100_of_my_code_for_1_ye...
1•ukuina•9m ago•1 comments

Looking for 4 Autistic Co-Founders for AI Startup (Equity-Based)

1•au-ai-aisl•19m ago•1 comments

AI-native capabilities, a new API Catalog, and updated plans and pricing

https://blog.postman.com/new-capabilities-march-2026/
1•thunderbong•20m ago•0 comments

What changed in tech from 2010 to 2020?

https://www.tedsanders.com/what-changed-in-tech-from-2010-to-2020/
2•endorphine•25m ago•0 comments

From Human Ergonomics to Agent Ergonomics

https://wesmckinney.com/blog/agent-ergonomics/
1•Anon84•28m ago•0 comments

Advanced Inertial Reference Sphere

https://en.wikipedia.org/wiki/Advanced_Inertial_Reference_Sphere
1•cyanf•30m ago•0 comments

Toyota Developing a Console-Grade, Open-Source Game Engine with Flutter and Dart

https://www.phoronix.com/news/Fluorite-Toyota-Game-Engine
1•computer23•32m ago•0 comments

Typing for Love or Money: The Hidden Labor Behind Modern Literary Masterpieces

https://publicdomainreview.org/essay/typing-for-love-or-money/
1•prismatic•33m ago•0 comments

Show HN: A longitudinal health record built from fragmented medical data

https://myaether.live
1•takmak007•35m ago•0 comments

CoreWeave's $30B Bet on GPU Market Infrastructure

https://davefriedman.substack.com/p/coreweaves-30-billion-bet-on-gpu
1•gmays•47m ago•0 comments

Creating and Hosting a Static Website on Cloudflare for Free

https://benjaminsmallwood.com/blog/creating-and-hosting-a-static-website-on-cloudflare-for-free/
1•bensmallwood•52m ago•1 comments

"The Stanford scam proves America is becoming a nation of grifters"

https://www.thetimes.com/us/news-today/article/students-stanford-grifters-ivy-league-w2g5z768z
2•cwwc•57m ago•0 comments

Elon Musk on Space GPUs, AI, Optimus, and His Manufacturing Method

https://cheekypint.substack.com/p/elon-musk-on-space-gpus-ai-optimus
2•simonebrunozzi•1h ago•0 comments

X (Twitter) is back with a new X API Pay-Per-Use model

https://developer.x.com/
3•eeko_systems•1h ago•0 comments

Zlob.h 100% POSIX and glibc compatible globbing lib that is faste and better

https://github.com/dmtrKovalenko/zlob
3•neogoose•1h ago•1 comments

Show HN: Deterministic signal triangulation using a fixed .72% variance constant

https://github.com/mabrucker85-prog/Project_Lance_Core
2•mav5431•1h ago•1 comments

Scientists Discover Levitating Time Crystals You Can Hold, Defy Newton’s 3rd Law

https://phys.org/news/2026-02-scientists-levitating-crystals.html
3•sizzle•1h ago•0 comments

When Michelangelo Met Titian

https://www.wsj.com/arts-culture/books/michelangelo-titian-review-the-renaissances-odd-couple-e34...
1•keiferski•1h ago•0 comments

Solving NYT Pips with DLX

https://github.com/DonoG/NYTPips4Processing
1•impossiblecode•1h ago•1 comments

Baldur's Gate to be turned into TV series – without the game's developers

https://www.bbc.com/news/articles/c24g457y534o
3•vunderba•1h ago•0 comments

Interview with 'Just use a VPS' bro (OpenClaw version) [video]

https://www.youtube.com/watch?v=40SnEd1RWUU
2•dangtony98•1h ago•0 comments

EchoJEPA: Latent Predictive Foundation Model for Echocardiography

https://github.com/bowang-lab/EchoJEPA
1•euvin•1h ago•0 comments

Disablling Go Telemetry

https://go.dev/doc/telemetry
1•1vuio0pswjnm7•1h ago•0 comments

Effective Nihilism

https://www.effectivenihilism.org/
1•abetusk•1h ago•1 comments

The UK government didn't want you to see this report on ecosystem collapse

https://www.theguardian.com/commentisfree/2026/jan/27/uk-government-report-ecosystem-collapse-foi...
5•pabs3•1h ago•0 comments

No 10 blocks report on impact of rainforest collapse on food prices

https://www.thetimes.com/uk/environment/article/no-10-blocks-report-on-impact-of-rainforest-colla...
3•pabs3•1h ago•0 comments

Seedance 2.0 Is Coming

https://seedance-2.app/
1•Jenny249•1h ago•0 comments
Open in hackernews

'Turbocharged' Mitochondria Power Birds' Epic Migratory Journeys

https://www.quantamagazine.org/turbocharged-mitochondria-power-birds-epic-migratory-journeys-20250519/
78•pseudolus•8mo ago

Comments

coolcase•8mo ago
Wouldn't mind some bird mitochondria!
b800h•8mo ago
Seriously, what would happen if we swapped out human mitochondria from a zygote for bird mitochondria?
jyounker•8mo ago
I don't think you'd get the same sort of effects, because a huge part of the mitochondrial regulation and function is carried out by genes and gene products from outside the mitochondria.

It would be an interesting experiment though. I'd expect that they might not live, or that the cell would function sub-optimally, but who knows, maybe the cellular machinery is highly conserved.

dejj•8mo ago
Yes. Afaik from Nick Lane’s “Oxygen” the Cytochrome Oxidase made from the mitochondrial DNA have to match the Cytochrome C made from nuclear DNA. Even slight mismatch seems to lower mitochondrial performance and is a problem why heteroplasmy (mixing of mitochondria from father and mother) seems to be selected-out.
treyd•8mo ago
Well what if you also swapped out those genes?
dejj•8mo ago
If your mitochondria have bird DNA and your nucleus has bird DNA, then you’re a bird.

There’s an easier way. A single nucleotide polymorphism (SNP) that only and rarely is observed in Japanese can extend human lifespan greatly. Flip a single base pair. This seems the most promising first step for genetically engineering humans.

dghughes•8mo ago
You'd get Kids in the Hall Chicken Lady.
mckirk•8mo ago
And some whale blood!
ljf•8mo ago
Previously posted: https://news.ycombinator.com/item?id=44051652 (1 day ago, 78 comments)
rbanffy•8mo ago
Can the entries be merged?
EGreg•8mo ago
Can they? Yes. Should they? No.
rbanffy•8mo ago
Why have two separate discussions on the same topic a day apart?
gherkinnn•8mo ago
No layman's discussion about mitochondria is complete without the In Our Time episode on just that:

https://www.bbc.co.uk/programmes/m001md34

It is one of my favourites.

londons_explore•8mo ago
What is the typical lifespan of ATP within a cell?

Are we talking milliseconds or minutes?

pfdietz•8mo ago
According to the wikipedia page on ATP, the average ATP concentration in eukaryotic cells is 1 to 10 micromols per gram.

According to https://bionumbers.hms.harvard.edu/bionumber.aspx?s=n&v=2&id... a single mammalian cell has a mass of 3 to 4 nanograms.

Google AI tells me the average rate of ATP formation in a mammalian cell is around 10 million molecules per second.

The ratio here ranges from 3 to 40 minutes.

I imagine it varies greatly depending on cell type.

eitally•8mo ago
From an exercise physiology point of view, it's generally accepted that ATP-CP powered motility is possible for only about 10 seconds (that is to say, you only store enough ATP for about 10 seconds of high intensity work -- sprinting, maximal weight lifting, etc). After that, other energy systems become dominant ... both of which create ATP but depend on either glycolysis (anaerobic) or oxidative phosphorylation (aerobic) for the process/conversion.
ck2•8mo ago
vaguely related there is a fantastic new PBS Space Time this week which suggests the "no alien life" fermi paradox may be related to how our mitochondria evolved by a series of fortunate accidents which may not be reproducible elsewhere

https://www.pbs.org/video/is-there-a-simple-solution-to-the-...

( https://www.youtube.com/watch?v=abvzkSJEhKk )