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Inhibiting 15-PGDH blocks BBB deterioration and protects mice from Alzheimer's
https://www.pnas.org/doi/10.1073/pnas.2417224122
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pera
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3h ago
Comments
pera
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3h ago
Original title:
Inhibiting 15-PGDH blocks blood–brain barrier deterioration and protects mice from Alzheimer’s disease and traumatic brain injury
Noah's Mausoleum (Nakhchivan, Azerbaijan)
https://en.wikipedia.org/wiki/Noah%27s_Mausoleum_(Nakhchivan,_Azerbaijan)
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thunderbong
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2m ago
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0 comments
Ask HN: What are you working on? (May 2025)
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david927
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4m ago
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0 comments
Find the right movie to watch using Amphytheatre
https://www.amphytheatre.com
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alanke19
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5m ago
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1 comments
Without Roots: The Political Consequences of Collective Economic Shocks
https://www.cambridge.org/core/journals/american-political-science-review/article/without-roots-the-political-consequences-of-collective-economic-shocks/1BA32999CD907689CA66A6CB06B8519B
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Traces
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5m ago
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0 comments
What if you got a device that cured ADHD like Modafinil with o side-effects?
https://www.nionneuroscience.com/
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PatrikSlachta
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7m ago
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1 comments
FreeBSD: The Report of My Death Was an Exaggeration
https://freebsdfoundation.org/blog/the-report-of-my-death-was-an-exaggeration/
2
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fork-bomber
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7m ago
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0 comments
Scheming Reasoning Evaluations
https://www.apolloresearch.ai/research/scheming-reasoning-evaluations
1
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matthberg
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14m ago
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0 comments
Beware the Complexity Merchants
https://chrlschn.dev/blog/2025/05/beware-the-complexity-merchants/
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kiyanwang
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15m ago
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0 comments
Microsoft will stop accepting new third-party print drivers in Windows (2023)
https://arstechnica.com/gadgets/2023/09/microsoft-will-stop-accepting-new-third-party-print-drivers-in-windows/
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w3ll_w3ll_w3ll
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16m ago
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0 comments
Deep Dive: How JPMorgan Is Reengineering Banking at Scale
https://www.fintechwrapup.com/p/deep-dive-how-jpmorgan-is-reengineering
1
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siroj
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16m ago
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0 comments
Judges Weigh Taking Control of Their Own Security Amid Threats
https://www.wsj.com/us-news/law/trump-judges-security-marshals-6e080ac6
2
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layer8
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16m ago
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1 comments
Why People Quit – and How Great Managers Make Them Want to Stay
https://kimmalonescott.medium.com/why-people-really-quit-and-how-great-managers-make-them-want-to-stay-d332dbf0d7b3
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kiyanwang
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18m ago
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0 comments
Idea: A competitive Tetris variant using a single grid
1
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amichail
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20m ago
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1 comments
Vibe Coding for Domain Experts
https://thescoop.org/archives/2025/05/24/vibe-coding-for-domain-experts/index.html
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stereo
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22m ago
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1 comments
Show HN: Generate SVGs with AI
https://vectorart.ai
5
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tm11zz
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24m ago
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0 comments
Integrated Combined Cycle Turbine-Ramjet-Scramjet-Rocket Engine
https://www.academia.edu/99126113/Integrated_Combined_Cycle_Turbine_Ramjet_Scramjet_Rocket_Engine
2
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rbanffy
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27m ago
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0 comments
Stop Looking for Mentors(2021)
https://staysaasy.com/career/2021/10/16/mentorship.html
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thisismytest
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30m ago
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0 comments
Gemma 3n Architectural Innovations – Speculation and poking around in the model
https://old.reddit.com/r/LocalLLaMA/comments/1kuy45r/gemma_3n_architectural_innovations_speculation/
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nolist_policy
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33m ago
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0 comments
Indian police try to read suspects' minds, over neuroscientists' objections
https://www.science.org/content/article/indian-police-are-trying-read-minds-suspects-over-neuroscientists-objections
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mmooss
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37m ago
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0 comments
C++ – pragma once vs. include guards?
https://stackoverflow.com/questions/1143936/pragma-once-vs-include-guards
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quincepie
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39m ago
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0 comments
FAA gives SpaceX the nod for Starship Flight 9 but doubles the danger zone
https://www.theregister.com/2025/05/23/faa_spacex_starship_9/
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Bender
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40m ago
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0 comments
Signal Adds Screenshot-Blocker to Thwart 'Windows Recall'
https://www.securityweek.com/signal-adds-screenshot-blocker-to-thwart-windows-recall/
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Bender
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41m ago
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1 comments
DanaBot Botnet Disrupted, 16 Suspects Charged
https://www.securityweek.com/danabot-botnet-disrupted-by-law-enforcement-16-suspects-charged/
2
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Bender
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41m ago
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0 comments
Historic England Launches Local Heritage Hub to Unlock Hidden Histories
https://historicengland.org.uk/whats-new/news/local-heritage-hub-launches/
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gnabgib
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46m ago
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0 comments
I love 2025 because I can vibecode. What a time to be alive
2
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sankalpdomore
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46m ago
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2 comments
Breaking down Amazon's mega dropdown (2013)
https://bjk5.com/post/44698559168/breaking-down-amazons-mega-dropdown
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fidotron
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49m ago
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0 comments
Sam and Jony and Skepticism
https://sixcolors.com/post/2025/05/sam-and-jony-and-skepticism/
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kjhughes
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50m ago
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3 comments
SteamOS now released officially for any device
https://store.steampowered.com/steamos
10
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cultofmetatron
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50m ago
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3 comments
Show HN: Luma – Ship Docker Anywhere
https://github.com/elitan/luma
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elitan
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50m ago
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0 comments
Show HN: Catch hidden exceptions in JavaScript with ESLint and JSDoc
https://github.com/Xvezda/eslint-plugin-explicit-exceptions
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Xvezda
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52m ago
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0 comments
pera•3h ago