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A Tale of Two Standards, POSIX and Win32 (2005)

https://www.samba.org/samba/news/articles/low_point/tale_two_stds_os2.html
1•goranmoomin•1m ago•0 comments

Ask HN: Is the Downfall of SaaS Started?

1•throwaw12•2m ago•0 comments

Flirt: The Native Backend

https://blog.buenzli.dev/flirt-native-backend/
2•senekor•4m ago•0 comments

OpenAI's Latest Platform Targets Enterprise Customers

https://aibusiness.com/agentic-ai/openai-s-latest-platform-targets-enterprise-customers
1•myk-e•6m ago•0 comments

Goldman Sachs taps Anthropic's Claude to automate accounting, compliance roles

https://www.cnbc.com/2026/02/06/anthropic-goldman-sachs-ai-model-accounting.html
2•myk-e•9m ago•3 comments

Ai.com bought by Crypto.com founder for $70M in biggest-ever website name deal

https://www.ft.com/content/83488628-8dfd-4060-a7b0-71b1bb012785
1•1vuio0pswjnm7•10m ago•1 comments

Big Tech's AI Push Is Costing More Than the Moon Landing

https://www.wsj.com/tech/ai/ai-spending-tech-companies-compared-02b90046
1•1vuio0pswjnm7•12m ago•0 comments

The AI boom is causing shortages everywhere else

https://www.washingtonpost.com/technology/2026/02/07/ai-spending-economy-shortages/
1•1vuio0pswjnm7•13m ago•0 comments

Suno, AI Music, and the Bad Future [video]

https://www.youtube.com/watch?v=U8dcFhF0Dlk
1•askl•15m ago•1 comments

Ask HN: How are researchers using AlphaFold in 2026?

1•jocho12•18m ago•0 comments

Running the "Reflections on Trusting Trust" Compiler

https://spawn-queue.acm.org/doi/10.1145/3786614
1•devooops•23m ago•0 comments

Watermark API – $0.01/image, 10x cheaper than Cloudinary

https://api-production-caa8.up.railway.app/docs
1•lembergs•25m ago•1 comments

Now send your marketing campaigns directly from ChatGPT

https://www.mail-o-mail.com/
1•avallark•28m ago•1 comments

Queueing Theory v2: DORA metrics, queue-of-queues, chi-alpha-beta-sigma notation

https://github.com/joelparkerhenderson/queueing-theory
1•jph•40m ago•0 comments

Show HN: Hibana – choreography-first protocol safety for Rust

https://hibanaworks.dev/
5•o8vm•42m ago•0 comments

Haniri: A live autonomous world where AI agents survive or collapse

https://www.haniri.com
1•donangrey•43m ago•1 comments

GPT-5.3-Codex System Card [pdf]

https://cdn.openai.com/pdf/23eca107-a9b1-4d2c-b156-7deb4fbc697c/GPT-5-3-Codex-System-Card-02.pdf
1•tosh•56m ago•0 comments

Atlas: Manage your database schema as code

https://github.com/ariga/atlas
1•quectophoton•58m ago•0 comments

Geist Pixel

https://vercel.com/blog/introducing-geist-pixel
2•helloplanets•1h ago•0 comments

Show HN: MCP to get latest dependency package and tool versions

https://github.com/MShekow/package-version-check-mcp
1•mshekow•1h ago•0 comments

The better you get at something, the harder it becomes to do

https://seekingtrust.substack.com/p/improving-at-writing-made-me-almost
2•FinnLobsien•1h ago•0 comments

Show HN: WP Float – Archive WordPress blogs to free static hosting

https://wpfloat.netlify.app/
1•zizoulegrande•1h ago•0 comments

Show HN: I Hacked My Family's Meal Planning with an App

https://mealjar.app
1•melvinzammit•1h ago•0 comments

Sony BMG copy protection rootkit scandal

https://en.wikipedia.org/wiki/Sony_BMG_copy_protection_rootkit_scandal
2•basilikum•1h ago•0 comments

The Future of Systems

https://novlabs.ai/mission/
2•tekbog•1h ago•1 comments

NASA now allowing astronauts to bring their smartphones on space missions

https://twitter.com/NASAAdmin/status/2019259382962307393
2•gbugniot•1h ago•0 comments

Claude Code Is the Inflection Point

https://newsletter.semianalysis.com/p/claude-code-is-the-inflection-point
4•throwaw12•1h ago•2 comments

Show HN: MicroClaw – Agentic AI Assistant for Telegram, Built in Rust

https://github.com/microclaw/microclaw
1•everettjf•1h ago•2 comments

Show HN: Omni-BLAS – 4x faster matrix multiplication via Monte Carlo sampling

https://github.com/AleatorAI/OMNI-BLAS
1•LowSpecEng•1h ago•1 comments

The AI-Ready Software Developer: Conclusion – Same Game, Different Dice

https://codemanship.wordpress.com/2026/01/05/the-ai-ready-software-developer-conclusion-same-game...
1•lifeisstillgood•1h ago•0 comments
Open in hackernews

SSRIs reduce plasma tau&restore dorsal raphe metabolism in Alzheimer's disease

https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.14579
2•bookofjoe•8mo ago

Comments

rubicon33•8mo ago
SSRIs are slowly but surely becoming a drug not too dissimilar to caffeine.

Benefits far outweigh the negatives for some (most?) people.

hollerith•8mo ago
Either that or they are a very profitable class of drugs and their owners have spent heavily to amplify the perception of benefits while downplaying the adverse effects.

I urge anyone considering a psych drug to do some research, and you can do a lot worse than watching some of the following YT channel, in which a psychiatrist conducts many interviews with people who claim to have been damaged by psych drugs including SSRIs: https://www.youtube.com/watch?v=fxZccQ7J-XA

rubicon33•8mo ago
Sure that's possible too (that research is heavily funded and swayed by the stake holders).

TBH though, over the last 20 years, I've seen enough to safely conclude for myself that SSRIs like Prozac are mostly harmless and probably have more benefits than drawbacks for the general population.

Coffee / caffeine falls into the same camp. Does it have drawbacks and side effects? Of course. Is it almost certainly a net-benefit? Yes.

So many other drugs where its very easy to say the opposite about. Alcohol for example, is mostly negative. My only recommendation for when to use alcohol is for ACUTE social situations. But even then, I recommend people work on their anxiety and self image before relying on alcohol for confidence. That said, it can be a silver bullet. Point is, everything is nuanced, everything has a plus and a negative.