What is very addictive, though, is the synergistic effect nicotine has with MAO inhibitors, such as those found in tobacco smoke or vape/gum/pouch flavorings.
Reinforcement and MAO-A inhibition in heated tobacco products: flavor and brand variations https://www.frontiersin.org/journals/psychiatry/articles/10....
Comparison of monoamine oxidase inhibition by cigarettes and modified risk tobacco products https://www.sciencedirect.com/science/article/pii/S221475001...
There is of course variance depending on the exact flavorants used. For example, menthol and mint flavors don’t inhibit MAO, their activity is towards kappa-opioid agonism (induction of dysphoria).
standardUser•6mo ago
Perhaps the true value of executives that justifies their bloated compensation is the ability to deliver bullshit lines like these with a straight face.