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Open Molten Claw: Post-Eval as a Service

https://idiallo.com/blog/open-molten-claw
1•watchful_moose•43s ago•0 comments

New York Budget Bill Mandates File Scans for 3D Printers

https://reclaimthenet.org/new-york-3d-printer-law-mandates-firearm-file-blocking
1•bilsbie•1m ago•0 comments

The End of Software as a Business?

https://www.thatwastheweek.com/p/ai-is-growing-up-its-ceos-arent
1•kteare•2m ago•0 comments

Exploring 1,400 reusable skills for AI coding tools

https://ai-devkit.com/skills/
1•hoangnnguyen•3m ago•0 comments

Show HN: A unique twist on Tetris and block puzzle

https://playdropstack.com/
1•lastodyssey•6m ago•0 comments

The logs I never read

https://pydantic.dev/articles/the-logs-i-never-read
1•nojito•7m ago•0 comments

How to use AI with expressive writing without generating AI slop

https://idratherbewriting.com/blog/bakhtin-collapse-ai-expressive-writing
1•cnunciato•9m ago•0 comments

Show HN: LinkScope – Real-Time UART Analyzer Using ESP32-S3 and PC GUI

https://github.com/choihimchan/linkscope-bpu-uart-analyzer
1•octablock•9m ago•0 comments

Cppsp v1.4.5–custom pattern-driven, nested, namespace-scoped templates

https://github.com/user19870/cppsp
1•user19870•10m ago•1 comments

The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•13m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•16m ago•3 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
2•sara_builds•16m ago•1 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•17m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•21m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•22m ago•0 comments

Hello

2•otrebladih•23m ago•1 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•26m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•28m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•29m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•31m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•35m ago•0 comments

.72% Variance Lance

1•mav5431•36m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•38m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•38m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•39m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•40m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•41m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•41m ago•2 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•42m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•42m ago•0 comments
Open in hackernews

Brain Freeze

https://asteriskmag.com/issues/10/brain-freeze
5•arielzj•7mo ago

Comments

arielzj•7mo ago
The idea of cryopreservation is simple and beautiful: When a person is beyond saving by modern methods, we can give them another lifeline. First, perfuse their bloodstream with antifreeze. Once administered, it’s possible to safely cool the body to incredibly low temperatures without ice forming inside organs and crushing delicate cells. Cold slows chemical reactions, all of them: According to the Arrhenius equation, every 10 °C decrease in temperature halves chemical reaction rates. A coolant like liquid nitrogen halves the ordinary rate of chemical reactions 22 times over. That stretches a single second of life into 48 days.

...

As you might expect, this simple idea turns out to be monstrously complicated and exacting in practice. The human body is much more finicky than the field’s founders in the 1960s had hoped. But the techniques exist. I’ve spent my life helping to develop them. The cryopreservation available today is far removed from the ideal — fussier, less elegant, and limited in what it can offer. There is much room for improvement and much work to be done. Still, it works, at least for a particular definition of working. We can’t yet warm up a frozen person and revive them, and it’s not certain we ever will. What we can do is reliably preserve memory in an information-theoretic sense. If our current understanding of neuroscience is correct, then we have the techniques to preserve all the information that makes a person who they are — albeit in a form that's impossible to extract with today's technology...

eamag•7mo ago
> I’ve spent my life helping to develop them

Can you share more?

arielzj•7mo ago
That's what's outlined in the article!

(Btw, I (OP) am not the writer of this piece, I'm just quoting it. But I am also a neuroscientist who's interested in brain preservation, for what it's worth.)

mandmandam•7mo ago
> If our current understanding of neuroscience is correct

I can promise you, it isn't. We're still finding new organs ffs.

arielzj•7mo ago
This is akin to saying that because we don't know how to unify general relativity and quantum mechanics, that we know nothing about physics. One can admit there's still a lot left to learn about a field while acknowledging the fundamentals might be reasonably well understood.
mandmandam•7mo ago
Are you claiming we understand the fundamentals of consciousness? ... I don't think that's remotely credible; and even the article doesn't make such a strong claim.
pu_pe•7mo ago
It's terrifying to think that due to the economics of this - ie controlled death, technical work done by specialists, decades of energy-stable cryopreservation -, it's mostly our present-day oligarchs who will be preserved and eventually immortalized.
arielzj•7mo ago
I don't think that's true at all. We routinely provide people with surgery by highly trained specialists and ongoing indefinite care while they're still biologically active. Outside of the US, this can even be done reasonably affordable. As far as medical procedures go, the one described here is fairly simple, and cold storage is also not that expensive. This should be accessible to anyone in a developed country.