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What rare disease AI teaches us about longitudinal health

https://myaether.live/blog/what-rare-disease-ai-teaches-us-about-longitudinal-health
1•takmak007•2m ago•0 comments

The Brand Savior Complex and the New Age of Self Censorship

https://thesocialjuice.substack.com/p/the-brand-savior-complex-and-the
1•jaskaransainiz•3m ago•0 comments

Show HN: A Prompting Framework for Non-Vibe-Coders

https://github.com/No3371/projex
1•3371•4m ago•0 comments

Kilroy is a local-first "software factory" CLI

https://github.com/danshapiro/kilroy
1•ukuina•14m ago•0 comments

Mathscapes – Jan 2026 [pdf]

https://momath.org/wp-content/uploads/2026/02/1.-Mathscapes-January-2026-with-Solution.pdf
1•vismit2000•16m ago•0 comments

80386 Barrel Shifter

https://nand2mario.github.io/posts/2026/80386_barrel_shifter/
2•jamesbowman•17m ago•0 comments

Training Foundation Models Directly on Human Brain Data

https://arxiv.org/abs/2601.12053
1•helloplanets•17m ago•0 comments

Web Speech API on HN Threads

https://toulas.ch/projects/hn-readaloud/
1•etoulas•20m ago•0 comments

ArtisanForge: Learn Laravel through a gamified RPG adventure – 100% free

https://artisanforge.online/
1•grazulex•20m ago•1 comments

Your phone edits all your photos with AI – is it changing your view of reality?

https://www.bbc.com/future/article/20260203-the-ai-that-quietly-edits-all-of-your-photos
1•breve•21m ago•0 comments

DStack, a small Bash tool for managing Docker Compose projects

https://github.com/KyanJeuring/dstack
1•kppjeuring•22m ago•1 comments

Hop – Fast SSH connection manager with TUI dashboard

https://github.com/danmartuszewski/hop
1•danmartuszewski•23m ago•1 comments

Turning books to courses using AI

https://www.book2course.org/
2•syukursyakir•24m ago•0 comments

Top #1 AI Video Agent: Free All in One AI Video and Image Agent by Vidzoo AI

https://vidzoo.ai
1•Evan233•24m ago•1 comments

Ask HN: How would you design an LLM-unfriendly language?

1•sph•26m ago•0 comments

Show HN: MuxPod – A mobile tmux client for monitoring AI agents on the go

https://github.com/moezakura/mux-pod
1•moezakura•27m ago•0 comments

March for Billionaires

https://marchforbillionaires.org/
1•gscott•27m ago•0 comments

Turn Claude Code/OpenClaw into Your Local Lovart – AI Design MCP Server

https://github.com/jau123/MeiGen-Art
1•jaujaujau•28m ago•0 comments

An Nginx Engineer Took over AI's Benchmark Tool

https://github.com/hongzhidao/jsbench/tree/main/docs
1•zhidao9•30m ago•0 comments

Use fn-keys as fn-keys for chosen apps in OS X

https://www.balanci.ng/tools/karabiner-function-key-generator.html
1•thelollies•30m ago•1 comments

Sir/SIEN: A communication protocol for production outages

https://getsimul.com/blog/communicate-outage-to-ceo
1•pingananth•31m ago•1 comments

Show HN: OpenCode for Meetings

https://getscripta.app
2•whitemyrat•32m ago•1 comments

The chaos in the US is affecting open source software and its developers

https://www.osnews.com/story/144348/the-chaos-in-the-us-is-affecting-open-source-software-and-its...
1•pjmlp•34m ago•0 comments

The world heard JD Vance being booed at the Olympics. Except for viewers in USA

https://www.theguardian.com/sport/2026/feb/07/jd-vance-boos-winter-olympics
66•treetalker•35m ago•14 comments

The original vi is a product of its time (and its time has passed)

https://utcc.utoronto.ca/~cks/space/blog/unix/ViIsAProductOfItsTime
1•ingve•43m ago•0 comments

Circumstantial Complexity, LLMs and Large Scale Architecture

https://www.datagubbe.se/aiarch/
1•ingve•50m ago•0 comments

Tech Bro Saga: big tech critique essay series

1•dikobraz•53m ago•0 comments

Show HN: A calculus course with an AI tutor watching the lectures with you

https://calculus.academa.ai/
1•apoogdk•56m ago•0 comments

Show HN: 83K lines of C++ – cryptocurrency written from scratch, not a fork

https://github.com/Kristian5013/flow-protocol
1•kristianXXI•1h ago•0 comments

Show HN: SAA – A minimal shell-as-chat agent using only Bash

https://github.com/moravy-mochi/saa
1•mrvmochi•1h ago•0 comments
Open in hackernews

Brain Freeze

https://asteriskmag.com/issues/10/brain-freeze
5•arielzj•7mo ago

Comments

arielzj•7mo ago
The idea of cryopreservation is simple and beautiful: When a person is beyond saving by modern methods, we can give them another lifeline. First, perfuse their bloodstream with antifreeze. Once administered, it’s possible to safely cool the body to incredibly low temperatures without ice forming inside organs and crushing delicate cells. Cold slows chemical reactions, all of them: According to the Arrhenius equation, every 10 °C decrease in temperature halves chemical reaction rates. A coolant like liquid nitrogen halves the ordinary rate of chemical reactions 22 times over. That stretches a single second of life into 48 days.

...

As you might expect, this simple idea turns out to be monstrously complicated and exacting in practice. The human body is much more finicky than the field’s founders in the 1960s had hoped. But the techniques exist. I’ve spent my life helping to develop them. The cryopreservation available today is far removed from the ideal — fussier, less elegant, and limited in what it can offer. There is much room for improvement and much work to be done. Still, it works, at least for a particular definition of working. We can’t yet warm up a frozen person and revive them, and it’s not certain we ever will. What we can do is reliably preserve memory in an information-theoretic sense. If our current understanding of neuroscience is correct, then we have the techniques to preserve all the information that makes a person who they are — albeit in a form that's impossible to extract with today's technology...

eamag•7mo ago
> I’ve spent my life helping to develop them

Can you share more?

arielzj•7mo ago
That's what's outlined in the article!

(Btw, I (OP) am not the writer of this piece, I'm just quoting it. But I am also a neuroscientist who's interested in brain preservation, for what it's worth.)

mandmandam•7mo ago
> If our current understanding of neuroscience is correct

I can promise you, it isn't. We're still finding new organs ffs.

arielzj•7mo ago
This is akin to saying that because we don't know how to unify general relativity and quantum mechanics, that we know nothing about physics. One can admit there's still a lot left to learn about a field while acknowledging the fundamentals might be reasonably well understood.
mandmandam•7mo ago
Are you claiming we understand the fundamentals of consciousness? ... I don't think that's remotely credible; and even the article doesn't make such a strong claim.
pu_pe•7mo ago
It's terrifying to think that due to the economics of this - ie controlled death, technical work done by specialists, decades of energy-stable cryopreservation -, it's mostly our present-day oligarchs who will be preserved and eventually immortalized.
arielzj•7mo ago
I don't think that's true at all. We routinely provide people with surgery by highly trained specialists and ongoing indefinite care while they're still biologically active. Outside of the US, this can even be done reasonably affordable. As far as medical procedures go, the one described here is fairly simple, and cold storage is also not that expensive. This should be accessible to anyone in a developed country.