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Low Sodium in Blood Triggers Anxiety in Mice by Disrupting Their Brain Chemistry

https://www.fujita-hu.ac.jp/en/news/respr20250612.html
17•gnabgib•5mo ago

Comments

pogue•5mo ago
I'd be curious to know how many people in the western world actually suffer from hyponatremia (low blood sodium) since it's so utterly pervasive in our diets to the point that most of us are probably close to hypernatremia on a daily basis. The American Heart Association recommends adults limit intake to no more than 2.3g (2300mg) of sodium per day. [1] A typical prepackaged meal, fast food, restaurant meal can often contain 1g or higher just in itself. Increased sodium intake for chronic peroids can lead to higher blood pressure [2] which may contribute to increased anxiety [3] [4]. While it's not necessarily always causative, we know some drugs that lower blood pressure also reduce anxiety (e.g.: propranolol [5]). But, there are cases where individuals can be consuming a lot of sodium from the diet and still losing it through sweat & other mechanisms and it could be contributing to anxiety. Stress can cause some people to pee more sodium out and others to retain more sodium! [6][7] Definitely another good reason to have regular blood work from a doctor.

[1] How much sodium should I eat per day? https://www.heart.org/en/healthy-living/healthy-eating/eat-s...

[2] Dietary salt and blood pressure: A complex connection https://www.health.harvard.edu/heart-health/dietary-salt-and...

[3] Stress and high blood pressure: What's the connection? https://www.mayoclinic.org/diseases-conditions/high-blood-pr...

[4] The Link Between Anxiety and High Blood Pressure https://www.verywellhealth.com/anxiety-high-blood-pressure-6...

[5] Beta-blockers for anxiety: What to know https://www.medicalnewstoday.com/articles/326397

[6] Can Stress Cause Low Sodium Levels? https://www.healthline.com/health/can-stress-cause-low-sodiu...

[7] The stress, salt excretion, and nighttime blood pressure (SABRE) study: Rationale and study design (2022)

"Exposure to an acute stressor (e.g., mental stress task) normally increases urinary sodium excretion. However, some individuals have sodium retention after stress provocation, revealing substantial between-person variability in the degree of stress-induced sodium excretion." https://www.sciencedirect.com/science/article/pii/S266660222...

AI-Driven Facial Recognition Leads to Innocent Man's Arrest (Bodycam Footage) [video]

https://www.youtube.com/watch?v=B9M4F_U1eEw
1•niczem•20s ago•1 comments

Annual Production of 1/72 (22mm) scale plastic soldiers, 1958-2025

https://plasticsoldierreview.com/ShowFeature.aspx?id=27
1•YeGoblynQueenne•1m ago•0 comments

Error-Handling and Locality

https://www.natemeyvis.com/error-handling-and-locality/
1•Theaetetus•2m ago•0 comments

Petition for David Sacks to Self-Deport

https://form.jotform.com/253464131055147
1•resters•2m ago•0 comments

Get found where people search today

https://kleonotus.com/
1•makenotesfast•5m ago•1 comments

Show HN: An early-warning system for SaaS churn (not another dashboard)

https://firstdistro.com
1•Jide_Lambo•5m ago•1 comments

Tell HN: Musk has never *tweeted* a guess for real identity of Satoshi Nakamoto

1•tokenmemory•6m ago•1 comments

A Practical Approach to Verifying Code at Scale

https://alignment.openai.com/scaling-code-verification/
1•gmays•8m ago•0 comments

Show HN: macOS tool to restore window layouts

https://github.com/zembutsu/tsubame
1•zembutsu•10m ago•0 comments

30 Years of <Br> Tags

https://www.artmann.co/articles/30-years-of-br-tags
1•FragrantRiver•17m ago•0 comments

Kyoto

https://github.com/stevepeak/kyoto
2•handfuloflight•18m ago•0 comments

Decision Support System for Wind Farm Maintenance Using Robotic Agents

https://www.mdpi.com/2571-5577/8/6/190
1•PaulHoule•18m ago•0 comments

Show HN: X-AnyLabeling – An open-source multimodal annotation ecosystem for CV

https://github.com/CVHub520/X-AnyLabeling
1•CVHub520•21m ago•0 comments

Penpot Docker Extension

https://www.ajeetraina.com/introducing-the-penpot-docker-extension-one-click-deployment-for-self-...
1•rainasajeet•22m ago•0 comments

Company Thinks It Can Power AI Data Centers with Supersonic Jet Engines

https://www.extremetech.com/science/this-company-thinks-it-can-power-ai-data-centers-with-superso...
1•vanburen•25m ago•0 comments

If AIs can feel pain, what is our responsibility towards them?

https://aeon.co/essays/if-ais-can-feel-pain-what-is-our-responsibility-towards-them
3•rwmj•29m ago•5 comments

Elon Musk's xAI Sues Apple and OpenAI over App Store Drama

https://mashable.com/article/elon-musk-xai-lawsuit-apple-openai
1•paulatreides•32m ago•1 comments

Ask HN: Build it yourself SWE blogs?

1•bawis•32m ago•1 comments

Original Apollo 11 Guidance Computer source code

https://github.com/chrislgarry/Apollo-11
3•Fiveplus•38m ago•0 comments

How Did the CIA Lose Nuclear Device?

https://www.nytimes.com/interactive/2025/12/13/world/asia/cia-nuclear-device-himalayas-nanda-devi...
1•Wonnk13•38m ago•0 comments

Is vibe coding the new gateway to technical debt?

https://www.infoworld.com/article/4098925/is-vibe-coding-the-new-gateway-to-technical-debt.html
1•birdculture•42m ago•1 comments

Why Rust for Embedded Systems? (and Why I'm Teaching Robotics with It)

https://blog.ravven.dev/blog/why-rust-for-embedded-systems/
2•aeyonblack•44m ago•0 comments

EU: Protecting children without the privacy nightmare of Digital IDs

https://democrats.eu/en/protecting-minors-online-without-violating-privacy-is-possible/
3•valkrieco•44m ago•0 comments

Using E2E Tests as Documentation

https://www.vaslabs.io/post/using-e2e-tests-as-documentation
1•lihaoyi•45m ago•0 comments

Apple Welcome Screen: iWeb

https://www.apple.com/welcomescreen/ilife/iweb-3/
1•hackerbeat•46m ago•1 comments

Accessible Perceptual Contrast Algorithm (APCA) in a Nutshell

https://git.apcacontrast.com/documentation/APCA_in_a_Nutshell.html
1•Kerrick•47m ago•0 comments

AI agent finds more security flaws than human hackers at Stanford

https://scienceclock.com/ai-agent-beats-human-hackers-in-stanford-cybersecurity-experiment/
3•ashishgupta2209•48m ago•2 comments

Nano banana prompts, updates everyday

https://github.com/fionalee1412/bestnanobananaprompt-github
4•AI_kid1412•52m ago•0 comments

Skills vs. Dynamic MCP Loadouts

https://lucumr.pocoo.org/2025/12/13/skills-vs-mcp/
3•cube2222•56m ago•0 comments

Top validated AI-SaaS Ideas are available here

1•peterbricks•1h ago•0 comments