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Effects of Zepbound on Stool Quality

https://twitter.com/ScottHickle/status/2020150085296775300
1•aloukissas•1m ago•0 comments

Show HN: Seedance 2.0 – The Most Powerful AI Video Generator

https://seedance.ai/
1•bigbromaker•4m ago•0 comments

Ask HN: Do we need "metadata in source code" syntax that LLMs will never delete?

1•andrewstuart•10m ago•1 comments

Pentagon cutting ties w/ "woke" Harvard, ending military training & fellowships

https://www.cbsnews.com/news/pentagon-says-its-cutting-ties-with-woke-harvard-discontinuing-milit...
2•alephnerd•12m ago•1 comments

Can Quantum-Mechanical Description of Physical Reality Be Considered Complete? [pdf]

https://cds.cern.ch/record/405662/files/PhysRev.47.777.pdf
1•northlondoner•13m ago•1 comments

Kessler Syndrome Has Started [video]

https://www.tiktok.com/@cjtrowbridge/video/7602634355160206623
1•pbradv•15m ago•0 comments

Complex Heterodynes Explained

https://tomverbeure.github.io/2026/02/07/Complex-Heterodyne.html
3•hasheddan•16m ago•0 comments

EVs Are a Failed Experiment

https://spectator.org/evs-are-a-failed-experiment/
2•ArtemZ•27m ago•4 comments

MemAlign: Building Better LLM Judges from Human Feedback with Scalable Memory

https://www.databricks.com/blog/memalign-building-better-llm-judges-human-feedback-scalable-memory
1•superchink•28m ago•0 comments

CCC (Claude's C Compiler) on Compiler Explorer

https://godbolt.org/z/asjc13sa6
2•LiamPowell•30m ago•0 comments

Homeland Security Spying on Reddit Users

https://www.kenklippenstein.com/p/homeland-security-spies-on-reddit
3•duxup•33m ago•0 comments

Actors with Tokio (2021)

https://ryhl.io/blog/actors-with-tokio/
1•vinhnx•34m ago•0 comments

Can graph neural networks for biology realistically run on edge devices?

https://doi.org/10.21203/rs.3.rs-8645211/v1
1•swapinvidya•46m ago•1 comments

Deeper into the shareing of one air conditioner for 2 rooms

1•ozzysnaps•48m ago•0 comments

Weatherman introduces fruit-based authentication system to combat deep fakes

https://www.youtube.com/watch?v=5HVbZwJ9gPE
3•savrajsingh•49m ago•0 comments

Why Embedded Models Must Hallucinate: A Boundary Theory (RCC)

http://www.effacermonexistence.com/rcc-hn-1-1
1•formerOpenAI•51m ago•2 comments

A Curated List of ML System Design Case Studies

https://github.com/Engineer1999/A-Curated-List-of-ML-System-Design-Case-Studies
3•tejonutella•55m ago•0 comments

Pony Alpha: New free 200K context model for coding, reasoning and roleplay

https://ponyalpha.pro
1•qzcanoe•59m ago•1 comments

Show HN: Tunbot – Discord bot for temporary Cloudflare tunnels behind CGNAT

https://github.com/Goofygiraffe06/tunbot
2•g1raffe•1h ago•0 comments

Open Problems in Mechanistic Interpretability

https://arxiv.org/abs/2501.16496
2•vinhnx•1h ago•0 comments

Bye Bye Humanity: The Potential AMOC Collapse

https://thatjoescott.com/2026/02/03/bye-bye-humanity-the-potential-amoc-collapse/
3•rolph•1h ago•0 comments

Dexter: Claude-Code-Style Agent for Financial Statements and Valuation

https://github.com/virattt/dexter
1•Lwrless•1h ago•0 comments

Digital Iris [video]

https://www.youtube.com/watch?v=Kg_2MAgS_pE
1•vermilingua•1h ago•0 comments

Essential CDN: The CDN that lets you do more than JavaScript

https://essentialcdn.fluidity.workers.dev/
1•telui•1h ago•1 comments

They Hijacked Our Tech [video]

https://www.youtube.com/watch?v=-nJM5HvnT5k
2•cedel2k1•1h ago•0 comments

Vouch

https://twitter.com/mitchellh/status/2020252149117313349
40•chwtutha•1h ago•6 comments

HRL Labs in Malibu laying off 1/3 of their workforce

https://www.dailynews.com/2026/02/06/hrl-labs-cuts-376-jobs-in-malibu-after-losing-government-work/
4•osnium123•1h ago•1 comments

Show HN: High-performance bidirectional list for React, React Native, and Vue

https://suhaotian.github.io/broad-infinite-list/
2•jeremy_su•1h ago•0 comments

Show HN: I built a Mac screen recorder Recap.Studio

https://recap.studio/
1•fx31xo•1h ago•1 comments

Ask HN: Codex 5.3 broke toolcalls? Opus 4.6 ignores instructions?

1•kachapopopow•1h ago•0 comments
Open in hackernews

I've almost completely switched from "Python" to "uv run"

https://actinium226.substack.com/p/ive-almost-completely-switched-from
23•actinium226•7mo ago

Comments

ethagnawl•7mo ago
Same here. The ability to specify dependencies and interpreter versions in the script and have the runtime just (quickly!) sort out all of the boring, uninteresting, brittle business around shims, virtualenvs, dependencies et al is absolutely game changing. I'm sure there are sharp edges I haven't found yet and that there will still be cross-platform compatibility issues which crop up but those will be addressed in due time.
actinium226•7mo ago
Indeed, I've managed to find one cross-platform compatibility issue in that uv can't autoinstall python for musl for arm64, which I discovered when I tried to use it to install python in an alpine docker image on my M2 air. I didn't particularly need musl, I just wanted to save 50MB or so in my docker image so I went back to the slim version of the image I needed. But they're tracking this issue and there's so much effort going into making this tool better so I'm sure they'll get to it eventually.
Toritori12•7mo ago
I wish there was a way to force all deps to create folders in the same directory by default. Tired of seeing how many libraries feel entitled to write on your Home (which I like to have in a small partition and those big GB-sized files are not expected).
guappa•7mo ago
HOME=/tmp/ uv run
Toritori12•7mo ago
welp, nice simple solution lol, thanks!
jessekv•7mo ago
You can take it one step further and make the file executable and place this at the top of the file:

#!/usr/bin/env -S uv run

IshKebab•7mo ago
Yep, it's the only sane option. Using uv takes Python from "oh no it's Python; how many hours am I going to spend working around pip bugs" to "hmm I might actually choose to use Python for this!".
guappa•7mo ago
uv is owned by a startup. I would not depend on it because they will pull some weird monetisation scheme in a few years.

Same with pydantic, that is now doing AI.

Expurple•7mo ago
Well, kinda. I haven't used uv, so I'm not sure how strong the dependency (and the lock-in) is. But it looks like just a QoL tool that reads the standard pyproject.toml, etc. So, it shouldn't be that bad. And if the authors do something weird, you can always stay on an older version, fork it, or switch back to some alternative.
guappa•7mo ago
Considering how python is not very backwards compatibility friendly, that might not be an option.
Expurple•7mo ago
I think, this is only relevant for staying on an older version of uv? Which is only a temporary solution, in any ecosystem and in almost any situation. It's just "even more temporary" in Python :)

If your old preferred alternative becomes unmaintained in the meantime and starts suffering from the same problems, that's basically equivalent to having to maintain a fork of uv. With the difference that it may be already out-of-date when the uv fork happens

IshKebab•7mo ago
Yeah that's definitely a concern, but uv is SO much better than it would be totally mad to avoid it just for that reason. I would say it is also so much better that if Astral does go out of business or try to ruin it that a fork is almost inevitable.

It reminds me of WhatsApp vs SMS. Sure, WhatsApp is owned by one company, but it's so much better than SMS that nobody sane stuck around using SMS. And sure Facebook have eventually started ruining it with the AI integration and apparently ads soon, but we've had over 10 years of an amazingly reliable, well-designed and free messaging platform. Easily worth it. If `uv` gives us something similar I don't care if they screw it up eventually.