These cures always end up requiring immunosuppressants, which make them a non starter for most type 1 diabetics.
mlhpdx•7mo ago
From the article:
> But patients in the trial had to stay on drugs to prevent the immune system from destroying the new cells. Suppressing the immune system, he said, increases the risk of infections and, over the long term, can increase the risk of cancer.
Indeed. They’re going to need to be able to make this kind of therapy using the patient’s own stem cells if they want a market for it.
bilsbie•7mo ago
I remember seeing clinical trials on this 20-30 years ago. Why is it different now? What happened to those trials?
Trasmatta•7mo ago
mlhpdx•7mo ago
> But patients in the trial had to stay on drugs to prevent the immune system from destroying the new cells. Suppressing the immune system, he said, increases the risk of infections and, over the long term, can increase the risk of cancer.
Indeed. They’re going to need to be able to make this kind of therapy using the patient’s own stem cells if they want a market for it.