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What are memories made of? A survey of neuroscientists

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0326920
4•arielzj•4h ago

Comments

arielzj•4h ago
"Despite the last decade’s development of optogenetic methods for artificially manipulating engrams, and subsequent claims that there is a consensus that memories are stored in ensembles of synaptic connections, it remains unclear to what degree there truly is unanimity within the neuroscientific community about the neurophysiological basis of long-term memory. We surveyed 312 neuroscientists, comprising one cohort of experts on engram research and another of general neuroscientists, to assess this community’s views on how memories are stored. While 70.5% of participants agreed that long-term memories are primarily maintained by neuronal connectivity patterns and synaptic strengths, there was no clear consensus on which specific neurophysiological features or scales are critical for memory storage. Despite this, the median probability estimate that any long-term memories could potentially be extracted from a static snapshot of brain structure was around 40%, which was also the estimate for whether a successful whole brain emulation could theoretically be created from the structure of a preserved brain. When predicting the future feasibility of whole brain emulation, the median participant estimated this would be achieved for C. elegans around 2045, mice around 2065, and humans around 2125. Notably, neither research background nor expertise level significantly influenced views on whether memories could be extracted from brain structure alone. Our findings suggest that while most neuroscientists believe memories are stored in structural features of the brain, fundamental questions about the precise physical basis of memory storage remain unresolved. These findings have important implications for both theoretical neuroscience and the development of technologies aimed at preserving or extracting memory-related information."
arielzj•4h ago
tl;dr: neuroscientists think there's a 40% current brain preservation techniques work well enough (under ideal circumstances) to preserve someone's brain in a way that's potentially compatible with uploading them

Reddit vows to stay human to emerge a winner from artificial intelligence

https://www.ft.com/content/a86fb03a-8781-40b5-a077-1d677e546ecf
1•Brajeshwar•1m ago•0 comments

Ask HN: Laid-off devs who left tech?

4•phendrenad2•5m ago•0 comments

The universe is not based on information

https://secondsight.dev/2025/06/the-universe-is-not-based-on-information/
1•ffwd•5m ago•0 comments

Astronauts from India, Poland, Hungary blast off on a trip to the space station

https://apnews.com/article/spacex-axiom-india-hungary-poland-astronauts-d4a18fffaed4cfacf0c26157c98ef198
1•Brajeshwar•6m ago•0 comments

Show HN: I built a Binance Alpha Tool for points checking and airdrop tracking

https://www.binancealphatool.com
1•ManutdGTA•6m ago•0 comments

First NetHack ascension, and insights into the AI capabilities it requires

https://mikaelhenaff.substack.com/p/first-nethack-ascension-and-insights
1•JamesBarney•11m ago•0 comments

Why I don't ride the AI Hype Train

https://mertbulan.com/2025/06/26/why-i-dont-ride-the-ai-hype-train/
1•mertbio•12m ago•0 comments

NLnet Foundation announces 62 new projects for the NGI Zero Commons Fund

https://nlnet.nl/news/2025/20250624-announcement-grants-CommonsFund.html
1•pabs3•14m ago•0 comments

Ask HN: Is Cloud Run down for anyone else?

1•pasxizeis•14m ago•0 comments

Agent Lineage Evolution: A Novel Framework for Managing LLM Agent Degradation

https://danieltan.weblog.lol/2025/06/agent-lineage-evolution-a-novel-framework-for-managing-llm-agent-degradation
1•danieltanfh95•24m ago•1 comments

Show HN: A Free, Offline-First Cash Register That Runs in the Browser

https://takeasale.com/
1•gerardojbaez•25m ago•0 comments

Twenty (Open Source CRM) is out of beta

https://twenty.com/releases
1•pavl•29m ago•0 comments

More time in bed benefits morning and evening-type teens differently

https://www.psypost.org/more-time-in-bed-benefits-morning-and-evening-type-teens-differently-new-study-suggests/
1•lentoutcry•31m ago•0 comments

Clerk is down, and so are all apps using it

https://status.clerk.com
5•cheerioty•32m ago•2 comments

Donate Less

https://blogs.gnome.org/steven/2025/06/26/donate-less/
3•edent•33m ago•0 comments

Show HN: Mind maps in Visual Studio and VS Code with nodes linked to source code

https://codemindmap.com/
1•kentich•33m ago•0 comments

Pro-Indy accounts go dark after Israeli strikes

https://ukdefencejournal.org.uk/dozens-of-pro-indy-accounts-go-dark-after-israeli-strikes/
1•doener•34m ago•0 comments

We increased Roblox game profits by 30% using overlooked economic patterns

https://medium.com/@untouchable/theres-a-hidden-30-in-your-game-we-found-it-b394d5757163
5•HaunChangpeng•38m ago•1 comments

Clerk Is Down

https://clerk.com
1•wonderfuly•38m ago•0 comments

Show HN: Meeting Waste Calculator – See the Real Cost of Your Meetings

https://gitdigest.ai/meeting-waste
1•RaulOnRails•40m ago•0 comments

Seniors in Wheelchairs Zip-Tied and Arrested During Senate Budget Protest

https://centeredamerica.substack.com/p/breaking-seniors-in-wheelchairs-zip
1•lentoutcry•41m ago•0 comments

The European wood pigeon helped me appreciate its omnipresent city cousins

https://www.nytimes.com/2025/06/24/magazine/pigeons-city-nature.html
1•Thevet•42m ago•0 comments

Oldest boomerang doesn't come back

https://www.bbc.co.uk/news/articles/cren818q5x1o
2•ljf•45m ago•0 comments

Highbrow Climate Misinformation

https://josephheath.substack.com/p/highbrow-climate-misinformation
1•af78•48m ago•0 comments

CLI coding agents battle royale

https://twitter.com/SIGKITTEN/status/1937950811910234377
2•freediver•51m ago•0 comments

Amazon's Ring can now use AI to 'learn the routines of your residence'

https://www.theregister.com/2025/06/25/amazons_ring_ai_video_description/
4•detaro•52m ago•1 comments

A space for all people interested in gold and gold trading

https://www.xau-usd.space/
2•nonplayercaesar•56m ago•0 comments

Reverse Engineering the Microchip CLB Part 1: Background and Reverse Engineerin

http://mcp-clb.markomo.me/P1-Background-and-RE/
2•todsacerdoti•57m ago•0 comments

Gemini Users: We're Going to Look at Your Texts Whether You Like It or Not

https://gizmodo.com/google-to-gemini-users-were-going-to-look-at-your-texts-whether-you-like-it-or-not-2000620141
2•miles•57m ago•0 comments

Changes to Cody Free, Pro, and Enterprise Starter Plans

https://sourcegraph.com/blog/changes-to-cody-free-pro-and-enterprise-starter-plans
1•ingve•57m ago•0 comments