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The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•1m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•4m ago•2 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
1•sara_builds•4m ago•0 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•5m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•9m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•9m ago•0 comments

Hello

1•otrebladih•11m ago•0 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•13m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•15m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•17m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•19m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•23m ago•0 comments

.72% Variance Lance

1•mav5431•24m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•26m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•26m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•27m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•28m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•29m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•29m ago•1 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•30m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•30m ago•0 comments

South Korean crypto firm accidentally sends $44B in bitcoins to users

https://www.reuters.com/world/asia-pacific/crypto-firm-accidentally-sends-44-billion-bitcoins-use...
2•layer8•31m ago•0 comments

Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
1•atomic128•33m ago•2 comments

Web.whatsapp.com appears to be having issues syncing and sending messages

http://web.whatsapp.com
1•sabujp•33m ago•2 comments

Google in Your Terminal

https://gogcli.sh/
1•johlo•34m ago•0 comments

Shannon: Claude Code for Pen Testing: #1 on Github today

https://github.com/KeygraphHQ/shannon
1•hendler•35m ago•0 comments

Anthropic: Latest Claude model finds more than 500 vulnerabilities

https://www.scworld.com/news/anthropic-latest-claude-model-finds-more-than-500-vulnerabilities
2•Bender•39m ago•0 comments

Brooklyn cemetery plans human composting option, stirring interest and debate

https://www.cbsnews.com/newyork/news/brooklyn-green-wood-cemetery-human-composting/
1•geox•39m ago•0 comments

Why the 'Strivers' Are Right

https://greyenlightenment.com/2026/02/03/the-strivers-were-right-all-along/
1•paulpauper•41m ago•0 comments

Brain Dumps as a Literary Form

https://davegriffith.substack.com/p/brain-dumps-as-a-literary-form
1•gmays•41m ago•0 comments
Open in hackernews

Alice's Adventures in a Differentiable Wonderland

https://arxiv.org/abs/2404.17625
157•henning•7mo ago

Comments

fossa1•7mo ago
Glad to see JAX featured alongside PyTorch. JAX still feels like the best-kept secret in deep learning
ProofHouse•7mo ago
Damn beeeeefffffyyyyy. Need the month to eat ten pages a day, Tnx looks awesome. Could append diffusion too ultimately
superjose•7mo ago
Wow, kudos to the Author. Very easy to digest, beautifully crafted, and took the time to explain the concepts when most places take them for granted.
canyp•7mo ago
Well, kudos to your one-line comment too because now I am encouraged to actually read this.
magnio•7mo ago
This looks like a good practical companion for a more theoretical text, such as Deep Learning by Bishop.
kittikitti•7mo ago
Although I love this, it's not peer reviewed and I don't trust arxiv.
SiempreViernes•7mo ago
Actually, it is peer reviewed following the standard practice for books: some other people read it and provided feedback as evidenced by the Acknowledgments section.
esafak•7mo ago
People are submitting corrections: https://www.sscardapane.it/assets/alice/errata_list.pdf
odyssey7•7mo ago
It’s more a book than academic research.

The funny thing about books is that authors in free societies are allowed to self-publish whatever they want. The norms are different and, frankly, more democratic and with less gatekeeping.

ethan_smith•7mo ago
arXiv is a preprint server trusted by the scientific community for decades - papers there often undergo peer review later, and many top ML researchers publish their work there first for faster dissemination.
_giorgio_•7mo ago
Website of the author with more material and lab sessions

https://www.sscardapane.it/alice-book/

https://sscardapane.notion.site/Guided-lab-sessions-18c25bd1...

odyssey7•7mo ago
It would be nice if arXiv included a small-layout pdf or native epub option for e-readers. Now that they serve the Tex files and are experimenting with HTML, it feels like a natural step.
solarwindy•7mo ago
I think the version hosted on the book's website would work fine on smaller screens (and also seems to have been updated more recently):

https://www.sscardapane.it/assets/alice/Alice_book_volume_1....

0cf8612b2e1e•7mo ago

  The corresponding row vector is denoted by x^T when we need to distinguish them. We can also ignore the transpose for readability, if the shape is clear from context.
I am tilting at windmills, but I am continually annoyed at the sloppiness of mathematicians in writing. Fine, you don’t like verbosity, but for didactic purposes, please do not assume the reader is equipped to know that variable x actually implies variable y.

All that being said, the writing style from the first chapter is very encouraging at how approachable this will be.

JadeNB•7mo ago
> I am tilting at windmills, but I am continually annoyed at the sloppiness of mathematicians in writing. Fine, you don’t like verbosity, but for didactic purposes, please do not assume the reader is equipped to know that variable x actually implies variable y.

I am a practicing mathematician who felt the same way you did when I started, and who still writes their papers in a way that many of my colleagues feel is gallingly pedantic. With that as my credentials, I hope I may say that it can be much worse as a reader to read something where every detail is spelled out, because a bit of syntactic sugar begins to seem as important as the heart of an argument. Where the dividing line is between precision and obfuscation depends on the reader, and so inevitably will leave some readers on the wrong side, but a trade-off does have to be made somewhere.

prisenco•7mo ago
Could there be a compromise where the verbosity is kept but the key points are highlighted, grouped or presented in a different color.

I would certainly appreciate if math papers were more explicit and "hand-holding" but understand why trained mathematicians would find that tedious.

JadeNB•7mo ago
> Could there be a compromise where the verbosity is kept but the key points are highlighted, grouped or presented in a different color.

There's no reason except inertia why there couldn't be. Lamport actually proposed a system for this: https://lamport.azurewebsites.net/pubs/lamport-how-to-write.....

zmgsabst•7mo ago
I wish the formality would be included in an appendix — as someone who has had to implement a lot of things (and more than once, found errors).

But I agree with your general point: understanding the recipe and general thrust of the approach is often more important, because even if the exact proof misses some technical detail, that can often be patched.

JadeNB•7mo ago
> I wish the formality would be included in an appendix — as someone who has had to implement a lot of things (and more than once, found errors).

Indeed. Lamport says that this was part of what inspired his interest in formal proofs: https://mathoverflow.net/questions/35727/community-experienc....

runeblaze•7mo ago
It is weird to be honest. I first learned Coq and then started taking upper level maths classes. My group theory proofs were panned by my TAs as overly verbose, very precise, and I was specializing on H_1 and H_2s everywhere and having IHns flying around like crazy because I could not fathom how one proves things without formally connecting things up.

Then my profs told me I was not “wrong”, but proofs or expositions are to most mathematicians not programs (ha! How did I not know. You teach me natural deduction and expect me not to program?), more like convincing arguments/prose. At some point one abstracts.

esperent•7mo ago
Humans, even talented mathematicians, have limited context. A big part of any mathematics text is abstraction for the sake of understanding. It can be confusing at first, but once you learn how to read mathematics with these abstractions in place, reading everything spelled out with great verbocity and pedantic accuracy is frustrating and tiring. You're forcing your eyes to parse and interpret a whole bunch of symbols that your brain doesn't need.

Of course, some mathematicians take it too far and use these abstractions to obfuscate and prove how smart they are. Like everything, it's a balance.

I personally wasn't a fan of this particular shorthand when I read this book but I got used to it quickly.

bwfan123•7mo ago
this 3 page classic [1] captures most of the core ideas and explains it in a manner anyone with basic calculus background can understand - "Learning representations by back-propagating errors"

[1] https://gwern.net/doc/ai/nn/1986-rumelhart-2.pdf

pstuart•7mo ago
I took calculus over 30 years ago and have never really used it -- I'll put your conjecture to test (sample size: 1). Will let you know if your conjecture is true ;-).
dunefox•7mo ago
And I just bought the physical book...
canyp•7mo ago
I do that all the time to support authors, plus the physicality of a tangible book is irreplaceable. In fact, I did that just today with a different book.
canyp•7mo ago
Beautifully formatted and has the right combination of code and theory for noobs like me. Strong vibes for Simone right now, hero of the people.