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Aging-related inflammation is not universal across human populations

https://www.publichealth.columbia.edu/news/aging-related-inflammation-not-universal-across-human-populations
64•XzetaU8•5h ago

Comments

adrianN•3h ago
It is my understanding that we have tried anti inflammatory interventions and they didn’t help. So the conclusion that inflammation per se is not the problem seems to check out.
amelius•2h ago
Are you sure the side effects of the interventions were not the problem?
k__•2h ago
I dimmly remember Japanese research about how fasting induced autophagy could help.
elcritch•34m ago
There’s dozens of pro-inflammatory signaling proteins. Our anti-inflammatories really only target a small subset of them.

Ideally you need to stop inflammatory signals at the source, but we understand very few of those.

kpmcc•2h ago
If anyone wants an interesting read on inflammation / stress for lay audiences, I'd recommend 'Why Zebras Don't Get Ulcers' by Sapolsky.
amelius•2h ago
Thanks. Does it provide workable solutions? :)
koolhead17•1h ago
surprisingly, yes :)
dapperdrake•13m ago
Sometimes the world is really just black and white.

Opioid pills discovered in US-backed food aid

https://www.middleeasteye.net/news/opioid-pills-discovered-us-backed-food-aid-gaza-authorities-say
1•0x54MUR41•6s ago•0 comments

Ubuntu and Tuxedo duke it out for Linux on Snapdragon X Elite laptops

https://www.pcworld.com/article/2831829/ubuntu-and-tuxedo-duke-it-out-for-linux-on-snapdragon-x-elite-laptops.html
1•teleforce•1m ago•0 comments

GitHub CEO: Why Now Is the Best Time to Be a Developer [video]

https://www.youtube.com/watch?v=PR__eFQsnhg
1•quaintdev•2m ago•0 comments

Bcachefs may be dropped from the Linux kernel

https://www.theregister.com/2025/07/01/bcachefs_may_get_dropped/
1•LorenDB•2m ago•0 comments

8 Lines of Code [video]

https://www.infoq.com/presentations/8-lines-code-refactoring/
1•alexzeitler•2m ago•0 comments

Space is hard. There is no excuse for pretending it's easy

https://spacenews.com/space-is-hard-there-is-no-excuse-for-pretending-its-easy/
1•throw0101b•4m ago•0 comments

Boring Benchmarks: Rocky Linux 10 and AlmaLinux 10 Performance Against RHEL 10

https://www.phoronix.com/review/almalinux-10-rocky-linux-10
1•teleforce•4m ago•0 comments

You MUST listen to RFC 2119

https://ericwbailey.website/published/you-must-listen-to-rfc-2119/
1•mooreds•5m ago•0 comments

Evernox – Visual Database Diagrams, AI SQL, and BigQuery Migrations in One Tool

https://www.evernox.com/
3•maidmor•9m ago•0 comments

Enhancing Stock Price Prediction Through Integration of Astrological Data

https://www.sciencedirect.com/science/article/pii/S1877050925017521
2•f3r3nc•14m ago•0 comments

I was forgetting too much, so I'm building a WhatsApp bot to to help

https://nagser.com/
2•luclom•19m ago•3 comments

Runestone That May Be North America's Oldest Turns Up in a Canada Forest

https://www.nytimes.com/2025/06/27/world/canada/canada-runestone-ontario.html
3•pseudolus•23m ago•2 comments

Finding and understanding bugs in C compilers [pdf]

https://www.cse.unr.edu/~fredh/class/460/S2013/class/Papers/tanna.pdf
1•todsacerdoti•24m ago•0 comments

Seven Ways to Call United Airline

https://leatherworker.net/forum/topic/130188-seven-ways-to-call-united-airlines%C2%AE%EF%B8%8F-usa-contact-numbers-%E2%80%93-the-complete-guide/
1•sofiasofi•25m ago•0 comments

Show HN: Voxica – Bring your own voice to immersive audio storytelling

https://www.voxica.io/
1•sidearea•25m ago•0 comments

From an idea to an ML paper in under 1 hour

https://letters.lossfunk.com/p/from-an-idea-to-an-ml-paper-in-under
1•paraschopra•28m ago•0 comments

Context Engineering for Agents

https://rlancemartin.github.io/2025/06/23/context_engineering/
3•0x79de•33m ago•0 comments

Stop manually pentesting. I built an AI that thinks like a red team

https://www.zenthex.online
1•Rhaast•35m ago•1 comments

The Border Politics of Patents and the Immigrant Inventor

https://texaslawreview.org/the-border-politics-of-patents-and-the-immigrant-inventor/
1•woldemariam•36m ago•0 comments

ASCIIMoon: The moon's phase live in ASCII art

https://asciimoon.com/
1•zayat•36m ago•0 comments

Love Arc but stuck on Chrome? Arc Stage brings the best of Arc to the browser

https://chromewebstore.google.com/detail/arc-stage-arc-experience/angnbhooekkhlmohcmnjmlhfogjlfgee
1•nanxiaobei•37m ago•0 comments

Cloudflare will now block AI crawlers by default

https://www.theverge.com/news/695501/cloudflare-block-ai-crawlers-default
6•crgwbr•43m ago•0 comments

Unregulated tech tests: Thiel, Altman and co want Freedom Cities

https://www.heise.de/en/news/Unregulated-tech-tests-Thiel-Altman-and-co-want-Freedom-Cities-10309862.html
3•antfarm•43m ago•0 comments

Crypto Gotchas: Domain Separation

https://gotchas.salusa.dev/domain_separation.html
2•r4um•44m ago•0 comments

Caching is an Abstraction, not an Optimization

https://buttondown.com/jaffray/archive/caching-is-an-abstraction-not-an-optimization/
2•samuel246•47m ago•0 comments

People have empathy with AI as long as they think it's human

https://www.theregister.com/2025/07/01/people_have_empathy_with_ai/
2•rntn•47m ago•1 comments

Combining jinja2-CLI with jq and environment variables

https://www.zufallsheld.de/2025/06/30/templating-jinja-cli/
1•zufallsheld•49m ago•0 comments

Ask HN: The Proof or Bluff paper. Can "AI" do math?

1•henryjcee•50m ago•0 comments

Scientists identify culprit behind biggest-ever U.S. honey bee die-off

https://www.science.org/content/article/scientists-identify-culprit-behind-biggest-ever-u-s-honeybee-die
3•pseudolus•54m ago•0 comments

Neutrino: Probing-Based eBPF-Like GPU Kernel Profiling

https://github.com/open-neutrino/neutrino
1•limoce•57m ago•0 comments