Yes if you don't need 3mb of JS sent across the wire for some basic interactions.

No if it's a legacy system that was built before Vanilla JS caught up and standardized a lot of what jQuery brought to the table.

I used to defend using JQuery, lol. But I can do what it does with normal Javascript or even HTMX.

What the other said. I would still use it I plan to do a lot of JS stuff, maybe.