frontpage.
newsnewestaskshowjobs

Made with ♥ by @iamnishanth

Open Source @Github

Open in hackernews

Show HN: Novaflow (YC S25) – AI Data Analyst for Life Science Researchers

https://www.novaflowapp.com/
1•amulya•8h ago
Hi HN! We're building Novaflow to help life scientists analyze their experimental data without needing to code. Life science researchers produce massive amounts of data, but analyzing it typically requires advanced coding skills, specialized knowledge, and heavy computational resources - all of which are in limited supply. The bottlenecks we've seen are striking: small labs spend over $100K/year per analyst while large labs spend millions, yet still outsource analysis due to sheer data volume. Most labs have a 5:1 ratio of experimentalists to analysts, creating constant backlogs. The core issue is that analyzing biological data requires both extensive coding knowledge and deep understanding of biological context. Most researchers have one or the other, rarely both. Making matters worse, existing tools are often custom-built, poorly maintained, and not scalable. Many researchers are stuck using analysis tools that are 15+ years old. We built Novaflow to put analysis capabilities directly back in researchers' hands. Here's how it works: researchers upload their raw data files (CSVs, FASTQs, HDF5s), ask questions in plain English like "What genes are most differentially expressed in this file?", and get instant, publication-ready plots. Behind the scenes, we use LLM-powered pipelines that generate and run the appropriate bioinformatics workflows. The technical challenge is ensuring scientific accuracy. We've built extensive validation systems to ensure the generated code produces reliable results. Every analysis comes with exportable Jupyter notebooks and reproducible Python code, so researchers can verify and modify our approach. What makes this different from general data analysis tools is the domain-specific understanding. When a researcher asks about differential expression, the system knows to apply appropriate statistical methods, normalizations, and generate the right visualizations - things that would require extensive configuration in generic tools. We're focusing on life scientists blocked by slow or missing bioinformatics support - academic labs doing genomics, transcriptomics, and proteomics work, biotech companies trying to accelerate R&D cycles with leaner teams, and clinical groups using high-throughput technologies. We'd love to hear from anyone who's dealt with similar bottlenecks in scientific computing.

Lorem Gibson

http://loremgibson.com/
1•DyslexicAtheist•21s ago•0 comments

Let Me Pay for Firefox

https://discourse.mozilla.org/t/let-me-pay-for-firefox/141297
1•csmantle•1m ago•0 comments

Ilion Framework: A Public Layer for Semantic Alignment with Truth

https://zenodo.org/records/15872577
1•ilion_identity•2m ago•1 comments

Episode with Stephen Kotkin, Stalin biographer and historian

https://twitter.com/dwarkesh_sp/status/1943352067575419283
1•hackandthink•6m ago•1 comments

Changelog Checker – Aggregate and Inspect Your Dependency Changelogs

https://github.com/MrNaif2018/changelog-checker
1•mrnaif•6m ago•1 comments

Ask HN: How are you productively using Claude code?

1•nocobot•12m ago•0 comments

In the Hallowed Place Where There's Only Darkness

https://www.vqronline.org/spring-2025/portfolios/hallowed-place-where-theres-only-darkness
1•srom•12m ago•0 comments

The Design and Implementation of Extensible Records for Rust in CGP

https://contextgeneric.dev/blog/extensible-datatypes-part-3/
2•todsacerdoti•19m ago•0 comments

Can Pittsburgh's Old Steel Mills Be Turned into Data Centers?

https://www.wsj.com/tech/ai/can-pittsburghs-old-steel-mills-be-turned-into-an-ai-hub-bb2dd8ff
1•perihelions•19m ago•0 comments

ISRO successfully conducts hot tests of Gaganyaan propulsion system

https://www.thehindu.com/sci-tech/science/isro-successfully-conducts-hot-tests-of-gaganyaan-propulsion-system/article69790839.ece
6•Bluestein•21m ago•0 comments

Why Lua Beats MicroPython for Serious Embedded Devs

https://www.embedded.com/why-lua-beats-micropython-for-serious-embedded-devs
2•willhschmid•24m ago•0 comments

What happens if we have our conversations with AI in public?

https://old.reddit.com/r/microsaas/comments/1lynaw7/what_happens_if_we_have_our_conversations_with_ai/
1•markdoppler•24m ago•1 comments

AI the Ripper

https://hugston.com/articles/AI_Ripper
1•trilogic•24m ago•0 comments

Can a daily nap do more harm than good?

https://www.rte.ie/brainstorm/2025/0704/1503253-napping-benefits-disadvantages-sleep-intertia/
1•austinallegro•28m ago•0 comments

Show HN: Euler and Fourier = Cognition?

https://ryukulogos.github.io/RAIN-html-easy-explanation/
2•RyukuLogos•30m ago•1 comments

Defold editor scripting in 1.10.4: scene editing

https://defold.com/2025/07/11/editor-scripting-update/
2•vlaaad•32m ago•0 comments

When AI Codes, What's Left for Me?

https://corecursive.com/coding-agents/
1•ibobev•33m ago•0 comments

How do you keep meetings productive and cost-effective?

https://capdrainapp.com
1•ronny_rebellion•33m ago•1 comments

Atopile – design circuit boards fast – with code

https://atopile.io/atopile/introduction
1•poly2it•34m ago•0 comments

Show HN: HNping 'remind me later' for HN via web push

https://hnping.com/
1•Galorious•44m ago•0 comments

Reading Neuromancer for the first time in 2025

https://mbh4h.substack.com/p/neuromancer-2025-review-william-gibson
6•keiferski•51m ago•1 comments

Who Is Pope Leo?

https://www.americamagazine.org/faith/2025/07/10/who-pope-leo-robert-prevost-251107
1•joules77•51m ago•0 comments

Leading your engineers towards an AI-assisted future

https://blog.thepete.net/blog/2025/06/26/leading-your-engineers-towards-an-ai-assisted-future/
1•r4um•56m ago•0 comments

Thoughts on Motivation and My 40-Year Career

https://charity.wtf/2025/07/09/thoughts-on-motivation-and-my-40-year-career/
1•r4um•57m ago•0 comments

Assumptions

http://theprogrammersparadox.blogspot.com/2025/07/assumptions.html
1•r4um•58m ago•0 comments

Sega Enterprises Ltd. vs. Accolade, Inc., 977 F.2d 1510 (9th Cir. 1992)

https://en.wikipedia.org/wiki/Sega_v._Accolade
1•Bluestein•1h ago•0 comments

UK graduates share their job-hunting woes amid the AI fallout

https://www.theguardian.com/money/2025/jul/13/student-debt-graduates-share-job-hunting-woes-ai-fallout
3•mykowebhn•1h ago•0 comments

Nearly two-thirds of UK workers turning to drink because of job pressures

https://news.sky.com/story/nearly-two-thirds-of-uk-workers-turning-to-drink-because-of-job-pressures-survey-says-13395997
3•austinallegro•1h ago•0 comments

Gmail AI hallucinates, distorts email contents

https://www.t-online.de/digital/aktuelles/id_100811852/gmail-fantasiert-googles-mail-programm-verfaelscht-fremde-inhalte.html
5•disentanglement•1h ago•0 comments

Show HN: TXT OS – Open-Source AI Reasoning, One Plain-Text File at a Time

https://github.com/onestardao/WFGY/tree/main/OS
7•TXTOS•1h ago•2 comments