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You are the reason I am not reviewing this PR

https://github.com/NixOS/nixpkgs/pull/479442
1•midzer•46s ago•0 comments

Show HN: FamilyMemories.video – Turn static old photos into 5s AI videos

https://familymemories.video
1•tareq_•2m ago•0 comments

How Meta Made Linux a Planet-Scale Load Balancer

https://softwarefrontier.substack.com/p/how-meta-turned-the-linux-kernel
1•CortexFlow•2m ago•0 comments

A Turing Test for AI Coding

https://t-cadet.github.io/programming-wisdom/#2026-02-06-a-turing-test-for-ai-coding
1•phi-system•2m ago•0 comments

How to Identify and Eliminate Unused AWS Resources

https://medium.com/@vkelk/how-to-identify-and-eliminate-unused-aws-resources-b0e2040b4de8
1•vkelk•3m ago•0 comments

A2CDVI – HDMI output from from the Apple IIc's digital video output connector

https://github.com/MrTechGadget/A2C_DVI_SMD
1•mmoogle•4m ago•0 comments

CLI for Common Playwright Actions

https://github.com/microsoft/playwright-cli
2•saikatsg•5m ago•0 comments

Would you use an e-commerce platform that shares transaction fees with users?

https://moondala.one/
1•HamoodBahzar•6m ago•1 comments

Show HN: SafeClaw – a way to manage multiple Claude Code instances in containers

https://github.com/ykdojo/safeclaw
2•ykdojo•9m ago•0 comments

The Future of the Global Open-Source AI Ecosystem: From DeepSeek to AI+

https://huggingface.co/blog/huggingface/one-year-since-the-deepseek-moment-blog-3
3•gmays•10m ago•0 comments

The Evolution of the Interface

https://www.asktog.com/columns/038MacUITrends.html
2•dhruv3006•11m ago•1 comments

Azure: Virtual network routing appliance overview

https://learn.microsoft.com/en-us/azure/virtual-network/virtual-network-routing-appliance-overview
2•mariuz•12m ago•0 comments

Seedance2 – multi-shot AI video generation

https://www.genstory.app/story-template/seedance2-ai-story-generator
2•RyanMu•15m ago•1 comments

Πfs – The Data-Free Filesystem

https://github.com/philipl/pifs
2•ravenical•18m ago•0 comments

Go-busybox: A sandboxable port of busybox for AI agents

https://github.com/rcarmo/go-busybox
3•rcarmo•19m ago•0 comments

Quantization-Aware Distillation for NVFP4 Inference Accuracy Recovery [pdf]

https://research.nvidia.com/labs/nemotron/files/NVFP4-QAD-Report.pdf
2•gmays•20m ago•0 comments

xAI Merger Poses Bigger Threat to OpenAI, Anthropic

https://www.bloomberg.com/news/newsletters/2026-02-03/musk-s-xai-merger-poses-bigger-threat-to-op...
2•andsoitis•20m ago•0 comments

Atlas Airborne (Boston Dynamics and RAI Institute) [video]

https://www.youtube.com/watch?v=UNorxwlZlFk
2•lysace•21m ago•0 comments

Zen Tools

http://postmake.io/zen-list
2•Malfunction92•24m ago•0 comments

Is the Detachment in the Room? – Agents, Cruelty, and Empathy

https://hailey.at/posts/3mear2n7v3k2r
2•carnevalem•24m ago•1 comments

The purpose of Continuous Integration is to fail

https://blog.nix-ci.com/post/2026-02-05_the-purpose-of-ci-is-to-fail
1•zdw•26m ago•0 comments

Apfelstrudel: Live coding music environment with AI agent chat

https://github.com/rcarmo/apfelstrudel
2•rcarmo•27m ago•0 comments

What Is Stoicism?

https://stoacentral.com/guides/what-is-stoicism
3•0xmattf•28m ago•0 comments

What happens when a neighborhood is built around a farm

https://grist.org/cities/what-happens-when-a-neighborhood-is-built-around-a-farm/
1•Brajeshwar•28m ago•0 comments

Every major galaxy is speeding away from the Milky Way, except one

https://www.livescience.com/space/cosmology/every-major-galaxy-is-speeding-away-from-the-milky-wa...
3•Brajeshwar•28m ago•0 comments

Extreme Inequality Presages the Revolt Against It

https://www.noemamag.com/extreme-inequality-presages-the-revolt-against-it/
2•Brajeshwar•28m ago•0 comments

There's no such thing as "tech" (Ten years later)

1•dtjb•29m ago•0 comments

What Really Killed Flash Player: A Six-Year Campaign of Deliberate Platform Work

https://medium.com/@aglaforge/what-really-killed-flash-player-a-six-year-campaign-of-deliberate-p...
1•jbegley•29m ago•0 comments

Ask HN: Anyone orchestrating multiple AI coding agents in parallel?

1•buildingwdavid•31m ago•0 comments

Show HN: Knowledge-Bank

https://github.com/gabrywu-public/knowledge-bank
1•gabrywu•36m ago•0 comments
Open in hackernews

High-resolution imaging method details nerves across a mouse’s body

https://www.nature.com/articles/d41586-025-02156-y
15•bookofjoe•6mo ago

Comments

bookofjoe•6mo ago
https://archive.ph/9swm5
krisoft•6mo ago
I assume, though it is unstated in the article, that to physically support the tissue while it is sliced it needs to be frozen solid? Or is it the chemical preparation which turns the carcas solid?

Which part of the process described here is novel? Is it the first time that someone integrated a slicer with a microscope? Or is it that they built a faster one than previously available?

dumb1224•6mo ago
Not an expert in this field, but from their website https://www.hfnl.ustc.edu.cn/detail?id=23165 They seemed to have developed a vibration-based slicer scanner 'Blockface-VISoR' to scan 600μm 3d image but cut 400μm each time repeatly to reconstruct full 3d image. It says it's hydrogel treated sample.

P.S the visualisation tool to explore and navigate the slices is quite awesome too https://mesoanatomy.org/mesomouse/