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Decomposition of phenotypic heterogeneity in autism show underlying programs

https://www.nature.com/articles/s41588-025-02224-z
2•paulpauper•4h ago

Comments

nialse•1h ago
The study makes subclasses of autism based on parent reported behavioral phenotypes in questionnaires. They find that the subclasses have different genetic characteristics. Importantly they do not initially map genetic characteristics to the subclasses, thus there is no prediction of autism (subclasses) from genetics. However it lends additional credibility to the notion that autism is rather the autisms, a set of disorders with similar behavioral profiles but different causes.

Magic and Divination in the Age of AI

https://www.newstatesman.com/technology/2025/07/magic-and-divination-in-the-age-of-ai
1•Bremblefremble•55s ago•0 comments

Data Contract CLI

https://github.com/datacontract/datacontract-cli
1•RebootStr•1m ago•0 comments

Simon Wardley – From here to there and back again

https://www.youtube.com/watch?v=hEjjCI3kTM4
1•RebootStr•2m ago•0 comments

Celebrating 40 years of chemical drawing with ChemDraw

https://www.compoundchem.com/2025/07/18/chemdraw/
1•sohkamyung•9m ago•0 comments

Upcoming deprecation of GitHub Command Palette feature preview

https://github.blog/changelog/2025-07-15-upcoming-deprecation-of-github-command-palette-feature-preview/
1•going_north•10m ago•0 comments

What Scientists Learned Scanning the Bodies of 100k Brits

https://www.bloomberg.com/news/articles/2025-07-18/what-scientists-learned-scanning-the-bodies-of-100-000-brits
1•helsinkiandrew•16m ago•1 comments

We Turned Claude AI into an L5 Data Scientist [video]

https://www.youtube.com/watch?v=i7dXSsm6ULw
1•rented_mule•17m ago•1 comments

Show HN: Macuse – Give Your AI Superpowers on macOS

https://macuse.app
1•ahonn•21m ago•0 comments

No level of alcohol consumption is safe for our health (2023)

https://www.who.int/europe/news/item/04-01-2023-no-level-of-alcohol-consumption-is-safe-for-our-health
1•doener•26m ago•0 comments

Understand What Whales Are Saying

https://www.projectceti.org
2•doener•28m ago•0 comments

An Epicyclic Clock

https://sophiehoulden.com/randomstuff/epitime/
1•fanf2•30m ago•0 comments

Sensitive Wikimedia databases have reportedly been hacked and leaked

https://wikipediasucks.co/forum/viewtopic.php?f=5&t=3520
1•kurtreed2•30m ago•0 comments

When Root Meets Immutable: OpenBSD Chflags vs. Log Tampering

https://rsadowski.de/posts/2025/openbsd-immutable-system-logs/
7•todsacerdoti•35m ago•2 comments

H-Nets – The Future

https://goombalab.github.io/blog/2025/hnet-future/
1•cubefox•41m ago•0 comments

Firmware for the open source Teufel Mynd speaker

https://github.com/teufelaudio/mynd-firmware
1•morsch•43m ago•0 comments

Implementing a Fast Tensor Core Matmul on the Ada Architecture

https://www.spatters.ca/mma-matmul
2•skidrow•46m ago•1 comments

Engineering the End of Work

https://schmud.de/posts/2025-07-15-engineering-end-of-work.html
2•Bogdanp•47m ago•0 comments

Compiler Explorer: An Essential Kernel Playground for CUDA Developers

https://developer.nvidia.com/blog/compiler-explorer-the-kernel-playground-for-cuda-developers/
1•skidrow•47m ago•0 comments

Creating custom kernels for the AMD MI300

https://huggingface.co/blog/mi300kernels
1•skidrow•48m ago•0 comments

Show HN: FigForm – Feel the power of Figma when creating customized forms

https://figform.io
1•aarondelasy•51m ago•0 comments

Run a server at home using Raspberry Pi and Tunnelmole

https://softwareengineeringstandard.com/2025/07/14/raspberry-pi-server/
1•aussieguy1234•54m ago•0 comments

Best Chrome Extension to Remove Paywall in 2025

https://puupnewsapp.com/chrome-extension-to-remove-paywall/
1•CodeWanderer•55m ago•0 comments

What's happening to Matlab? Or, "The slow demise of the engineering toolbox"

https://blog.pictor.us/whats-happening-to-matlab/
2•bauta-steen•56m ago•0 comments

Mnemonic Devices in Illuminated Manuscripts

https://twitter.com/AHomelyHouse/status/1945940846559338597
1•Michelangelo11•59m ago•0 comments

Decoding Secrets: How military medals exposed Russia's SIGINT network

https://checkfirst.network/decoding-secrets-through-symbols-how-military-insignia-revealed-russias-hidden-sigint-network/
2•amaury•1h ago•1 comments

Aardvark

https://en.wikipedia.org/wiki/Aardvark
2•simonebrunozzi•1h ago•0 comments

Show HN: Self-made web media player without <video> or <audio>

https://mediabunny.dev/examples/media-player/
6•vanilagy•1h ago•6 comments

Mediabunny, a pure-TypeScript replacement for FFmpeg for in-web media processing

https://mediabunny.dev/
3•vanilagy•1h ago•0 comments

Trump Targets "Woke" AI

https://www.wsj.com/tech/ai/white-house-prepares-executive-order-targeting-woke-ai-e68e8e24
1•timoth3y•1h ago•1 comments

Thoughts on External Memory for LLMs

https://medium.com/@chipiga86/thoughts-on-external-memory-for-llms-e2ee21be3292
1•rishikeshs•1h ago•0 comments