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Onboarding for Coding Agents

https://www.fuzzycomputer.com/posts/onboarding
1•Twixes•30s ago•0 comments

Ask HN: What's the Best Linux Laptop? (August 2025)

1•rufugee•2m ago•0 comments

Show HN: Break in Motion – a macOS app that helps you use your standing desk

https://www.breakinmotion.com/
1•salunmarvin•4m ago•0 comments

Efficiently Generating a Number in a Range (2018)

https://www.pcg-random.org/posts/bounded-rands.html
1•csense•4m ago•0 comments

A simple deployment setup for self-hosting personal projects

https://bimals.net/posts/self-hosting
1•bimals•6m ago•0 comments

Character Bitmap Graphics on the Pet 2001

https://www.masswerk.at/nowgobang/2025/character-bitmaps-on-the-pet2001
1•masswerk•6m ago•0 comments

Show HN: I'm a 13 year old who built a user feedback board for devs to ship fast

https://indiereq.com
1•aydinjoshi•7m ago•0 comments

Blood taken from Danish babies ended up in huge genetic study–without consent

https://www.science.org/content/article/blood-taken-danish-babies-ended-huge-genetic-study-without-consent
2•bookofjoe•8m ago•1 comments

Cadence Guilty, Pays $140M for Exporting Semi Design Tools to PRC Military Uni

https://www.justice.gov/opa/pr/cadence-design-systems-agrees-plead-guilty-and-pay-over-140-million-unlawfully-exporting
2•737min•10m ago•0 comments

Orthodox Calendar API

https://orthocal.info/api/
1•rgrieselhuber•11m ago•0 comments

Image Formation on the Shroud of Turin – A Digital 3D Approach

https://www.livescience.com/archaeology/shroud-of-turin-wasnt-laid-on-jesus-body-but-rather-a-sculpture-modeling-study-suggests
1•geox•12m ago•0 comments

Anandtech.com now redirects to its forums

https://forums.anandtech.com/
5•kmfrk•15m ago•1 comments

PatchworkOS: 64-bit NON-POSIX OS with "everything is a file" philosophy

https://github.com/KaiNorberg/PatchworkOS
2•thunderbong•15m ago•0 comments

The Parallel Lives of an AI Engineer

https://worksonmymachine.ai/p/the-parallel-lives-of-an-ai-engineer
1•Stwerner•16m ago•0 comments

Zuck's $1B Offer for Thinking Machines Person Revealed

https://www.wsj.com/tech/ai/meta-zuckerberg-ai-recruiting-fail-e6107555
3•bkls•21m ago•1 comments

NASA Employees Subject to Random Searches as Agency Becomes AI Police Mini-State

https://www.jalopnik.com/1928459/nasa-subjecting-employees-to-random-searches/
3•freedomben•23m ago•0 comments

What The Salt Path scandal means for the nature memoir

https://www.theguardian.com/books/2025/aug/02/the-end-of-the-road-what-the-salt-path-scandal-means-for-the-nature-memoir
3•mykowebhn•26m ago•0 comments

NYC housing lottery applicants' personal info exposed online in data breach

https://www.cbsnews.com/newyork/news/nyc-housing-lottery-applicants-data-breach/
1•impish9208•26m ago•0 comments

Understanding Energy Trading: Physical vs. Financial Markets

https://a115.co.uk/physical-vs-financial-energy-trading-guide-uk/
1•jd115•27m ago•0 comments

Executing arbitrary Python code from a comment

https://www.hacktron.ai/blog/posts/python-zip-confusion
1•Bogdanp•27m ago•0 comments

China state media says Nvidia must provide 'security proofs' to regain trust

https://www.reuters.com/world/china/china-state-media-says-nvidia-must-provide-security-proofs-regain-trust-2025-08-01/
3•eagleislandsong•33m ago•0 comments

Show HN: NaturalCron – Human-Readable Scheduling for .NET (With Fluent Builder)

https://github.com/hugoj0s3/NaturalCron
1•hugoj0s3•33m ago•0 comments

Searloc: Decentralized Searxng Search

https://searloc.org
1•MrWazaby•34m ago•1 comments

Applications That Work with Motif/Lesstif (2005)

https://lesstif.sourceforge.net/apps.html
1•hualapais•36m ago•0 comments

The Great Crime Paradox

https://www.ft.com/content/7488fe4c-5e1d-4b2b-adab-f42ad5273fc9
4•frereubu•38m ago•1 comments

The Summer of Codex

https://paylias.xyz/blog/building-with-codex
1•ziyadparekh•39m ago•0 comments

Building a New Package from Scratch – Cursor Heatmap Pt1

https://emacs.dyerdwelling.family/emacs/20250719094720-emacs--building-an-emacs-cursor-heatmap-pt1/
2•trelane•44m ago•0 comments

Show HN: Easily match your traffic sources to paying customers

https://www.getboone.com/
1•Lrodd•46m ago•0 comments

PyTorch in One Hour: From Tensors to Training Neural Networks on Multiple GPUs

https://sebastianraschka.com/teaching/pytorch-1h/
1•Anon84•49m ago•0 comments

Thank you HN: Your democracy discussion shaped our building

1•ff12wq111•50m ago•0 comments
Open in hackernews

New research finds that ivermectin could help control malaria transmission

https://www.ndm.ox.ac.uk/news/new-research-supports-ivermectin-as-an-effective-strategy-to-control-malaria-transmission
31•rguiscard•1h ago

Comments

kacesensitive•49m ago
Ivermectin has a surprisingly interesting origin, it was discovered in soil near a Japanese golf course and developed from a bacterium that kills parasites. It went on to treat diseases like river blindness and became widely used in both human and veterinary medicine. Despite all that, it’s definitely not some miracle drug or cure-all like some would have you believe. Though that didn’t stop my grandpa from stockpiling it after watching too many Fox News ads.
andy_ppp•43m ago
Yes, I really am always shocked by the Joe Rogans et. al. who spout off about random fad pharmaceuticals like this (with microscopic grains of truth that’s been twisted), they don’t even understand the basics of what is done to prove anything at all works effectively but in complete stupidity there’s a certainty I don’t think I have about anything.

People are more likely to believe Mel Gibson than a scientist on this stuff, it’s going to lead to absolute disaster.

ttoinou•41m ago
Of course but the real question is how good the competition / alternative to Joe Rogan is. If he replaces MSM (all their lies and manipulation), then he’s better, even if he has low proof for what he talks about
kennywinker•2m ago
Might makes right?

Success in a media marketplace is not the same as quality, honesty, or integrity.

ImHereToVote•31m ago
I believe it was a licensed MD who prescribed Ivermectin to him. It might be that we all have some parasites that worsen COVID immune reactions.
bamboozled•27m ago
Yet there was zero evidence to suggest it would work for COVID, and people like him going around saying it worked, or they had "good results", based on nothing. Then they caused a shortage of the drug in places it was needed. So he actually caused harm with his BS.

I also got a fairly early strain of COVID and didn't have Ivermectin and I got over it pretty easily too? I just thought I pushed it too hard in the gym and felt a bit tired. My cousin got it, ended up in hospital on Oxygen.

Joe Rogan is just a fool and a propagandist.

transcriptase•18m ago
Versus the experts, politicians, and media who in the exact same time period were still confidently stressing the importance of achieving herd immunity because if you got vaccinated you couldn’t get COVID, and therefore couldn’t transmit it to others.

For which there was zero evidence, turned out not to be true, and was later retconned to “it reduces the severity of symptoms”.

Or earlier when health officials said masks were unnecessary because there was zero evidence they were effective.

Or earlier when the WHO refused to even call it a pandemic and maintaining little risk until there were dozens of confirmed cases in every country on the planet and China already had field hospitals built.

bamboozled•12m ago
I didn't say the response was perfect and all advice was accurate, but neither is selling bullshit like Ivermectin for COVID with zero evidence it was effective.

It's wild to suggest the best way to deal with the next pandemic is less science, less experts. No it's more science and more experts, that's what's required to solve the next pandemic and climate change, and super bugs and more.

Your comment seems to suggest that we should throw away all knowledge and faith in institutions because the knowledge we had at the time of a very dynamic situation wasn't perfect or to your liking.

It's painful to read honestly.

Next pandemic, we should just try random off the shell treatments until we find something that sticks I guess. Screw the experts?

transcriptase•6m ago
No. Next time people like yourself should listen to what he actually said about certain topics versus what you were told he said by those with an axe to grind. Then you might temper your language and accusations of propaganda, or at least properly aim them in the opposite direction.
sharifhsn•2m ago
When you talk about politicians… are you including Donald Trump in that, who said that if you stop testing, we would actually have very few cases?

Donald Trump, who talked about injecting bleach and sunlight into people to treat COVID, doing real time word association instead of educating the public during a pandemic?

Donald Trump, who promoted hydroxycholoroquine as the miracle cure for COVID despite no evidence that it was?

Donald Trump, who had his son-in-law run a team of unqualified volunteers for a “supply chain task force” during a pandemic, who announced that the federal stockpile of medical supplies (previously understood to be available for the states) was only to be used by the federal government?

The pandemic was ended by the vaccine. Donald Trump could take credit for that, but he won’t because his base of supporters is knee-deep in conspiracy theories about it. How sad.

smallerfish•22m ago
Yes, and there are licensed MDs working for RFK specifically to demonize vaccines (while there are many other licensed MDs who see vaccines as being very positive and efficacious). A license doesn't make you right.
ImHereToVote•9m ago
I would rather trust an MD over a rando on the Internet sorry.
kennywinker•7m ago
Which licensed MD?

If there are 100 licensed MDs telling you it’s BS, and 1 telling you it’s a miracle cure…

bamboozled•29m ago
Golf is awesome...I know that much for sure.
gus_massa•18m ago
> it’s definitely not some miracle drug or cure-all like some would have you believe

I agree. Anyway, there is a nice post about Ivermectin in 2020 by Derek Lowe (In the Pipeline) https://www.science.org/content/blog-post/what-s-ivermectin the most relevant quotes are:

> The drug is effective against a wide number of parasites and arthropods in general

> Its ion-channel mechanism of action against parasites has no application to viruses.

vnchr•32m ago
The discoverers of ivermectin shared a Nobel Prize in 2015 [0] with a discoverer of a novel malaria treatment. Interesting coincidence.

[0] https://www.nobelprize.org/prizes/medicine/2015/press-releas...

walterbell•17m ago
https://www.medpagetoday.com/special-reports/features/116436

> Four states -- Tennessee, Arkansas, Idaho, and Louisiana -- have passed OTC ivermectin laws

> [Nine] other states have bills moving through their legislatures

RagnarD•15m ago
Contrary to the smug claims that Ivermectin has no antiviral activity, it certainly does - along with some other antiparasitics. AFAIK the mechanism of action is still not entirely understood, but the evidence exists. The antiviral activity was being uncontroversially actively studied prior to the Covid pandemic, then actively smeared for political reasons because it's a cheap unpatented drug (which also has a much higher LD50 than over the counter Tylenol.)
tptacek•12m ago
It wasn't being "smeared for political reasons"; people were actively taking Ivermectin in preference to vaccines and therapeutics we knew worked on COVID. Whatever else Ivermectin might do, it was not a meaningful therapeutic for COVID.
RagnarD•3m ago
Of course it was (and is.) When properly dosed the risk is absolutely minimal. This is in stark contrast to the mRNA vaccines. (Paxlovid has value and is much safer than molnupiravir, which is deliberately mutagenic.)

As far as scientific evidence goes, this is one paper of many: https://www.nature.com/articles/s41429-020-0336-z