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Arcan Explained – A browser for different webs

https://arcan-fe.com/2026/01/26/arcan-explained-a-browser-for-different-webs/
1•walterbell•1m ago•0 comments

We are not scared of AI, we are scared of irrelevance

https://adlrocha.substack.com/p/adlrocha-we-are-not-scared-of-ai
1•adlrocha•2m ago•0 comments

Quartz Crystals

https://www.pa3fwm.nl/technotes/tn13a.html
1•gtsnexp•5m ago•0 comments

Show HN: I built a free dictionary API to avoid API keys

https://github.com/suvankar-mitra/free-dictionary-rest-api
2•suvankar_m•7m ago•0 comments

Show HN: Kybera – Agentic Smart Wallet with AI Osint and Reputation Tracking

https://kybera.xyz
1•xipz•8m ago•0 comments

Show HN: brew changelog – find upstream changelogs for Homebrew packages

https://github.com/pavel-voronin/homebrew-changelog
1•kolpaque•12m ago•0 comments

Any chess position with 8 pieces on board and one pair of pawns has been solved

https://mastodon.online/@lichess/116029914921844500
1•baruchel•14m ago•1 comments

LLMs as Language Compilers: Lessons from Fortran for the Future of Coding

https://cyber-omelette.com/posts/the-abstraction-rises.html
2•birdculture•16m ago•0 comments

Projecting high-dimensional tensor/matrix/vect GPT–>ML

https://github.com/tambetvali/LaegnaAIHDvisualization
1•tvali•16m ago•1 comments

Show HN: Free Bank Statement Analyzer to Find Spending Leaks and Save Money

https://www.whereismymoneygo.com/
2•raleobob•20m ago•1 comments

Our Stolen Light

https://ayushgundawar.me/posts/html/our_stolen_light.html
2•gundawar•20m ago•0 comments

Matchlock: Linux-based sandboxing for AI agents

https://github.com/jingkaihe/matchlock
1•jingkai_he•23m ago•0 comments

Show HN: A2A Protocol – Infrastructure for an Agent-to-Agent Economy

1•swimmingkiim•27m ago•1 comments

Drinking More Water Can Boost Your Energy

https://www.verywellhealth.com/can-drinking-water-boost-energy-11891522
1•wjb3•31m ago•0 comments

Proving Laderman's 3x3 Matrix Multiplication Is Locally Optimal via SMT Solvers

https://zenodo.org/records/18514533
1•DarenWatson•33m ago•0 comments

Fire may have altered human DNA

https://www.popsci.com/science/fire-alter-human-dna/
4•wjb3•33m ago•1 comments

"Compiled" Specs

https://deepclause.substack.com/p/compiled-specs
1•schmuhblaster•38m ago•0 comments

The Next Big Language (2007) by Steve Yegge

https://steve-yegge.blogspot.com/2007/02/next-big-language.html?2026
1•cryptoz•39m ago•0 comments

Open-Weight Models Are Getting Serious: GLM 4.7 vs. MiniMax M2.1

https://blog.kilo.ai/p/open-weight-models-are-getting-serious
4•ms7892•49m ago•0 comments

Using AI for Code Reviews: What Works, What Doesn't, and Why

https://entelligence.ai/blogs/entelligence-ai-in-cli
3•Arindam1729•50m ago•0 comments

Show HN: Solnix – an early-stage experimental programming language

https://www.solnix-lang.org/
2•maheshbhatiya•50m ago•0 comments

DoNotNotify is now Open Source

https://donotnotify.com/opensource.html
5•awaaz•51m ago•2 comments

The British Empire's Brothels

https://www.historytoday.com/archive/feature/british-empires-brothels
2•pepys•52m ago•0 comments

What rare disease AI teaches us about longitudinal health

https://myaether.live/blog/what-rare-disease-ai-teaches-us-about-longitudinal-health
2•takmak007•57m ago•0 comments

The Brand Savior Complex and the New Age of Self Censorship

https://thesocialjuice.substack.com/p/the-brand-savior-complex-and-the
2•jaskaransainiz•59m ago•0 comments

Show HN: A Prompting Framework for Non-Vibe-Coders

https://github.com/No3371/projex
2•3371•59m ago•0 comments

Kilroy is a local-first "software factory" CLI

https://github.com/danshapiro/kilroy
2•ukuina•1h ago•0 comments

Mathscapes – Jan 2026 [pdf]

https://momath.org/wp-content/uploads/2026/02/1.-Mathscapes-January-2026-with-Solution.pdf
1•vismit2000•1h ago•0 comments

80386 Barrel Shifter

https://nand2mario.github.io/posts/2026/80386_barrel_shifter/
2•jamesbowman•1h ago•0 comments

Training Foundation Models Directly on Human Brain Data

https://arxiv.org/abs/2601.12053
1•helloplanets•1h ago•0 comments
Open in hackernews

Artificial biosensor can better measure the body's main stress hormone

https://medicalxpress.com/news/2025-07-artificial-biosensor-body-main-stress.html
79•PaulHoule•6mo ago

Comments

camillomiller•5mo ago
I would apply the usual grain of salt approach to studies like these, but this one sounds insanely promising. Watching it closely
avidiax•5mo ago
This is certainly an improvement over a lab test, but a continuous monitoring solution would dramatically expand the utility.

You could rate employers on the median cortisol levels of their employees during and after the work day.

At an individual level, those of us that are not very self-aware of our stress levels could monitor it objectively and determine stressors and implement and monitor interventions to reduce stress.

IHLayman•5mo ago
Oh sure! While we’re at it, let’s increase the existing dystopia by giving employers the ability to track our stress levels and let them “compensate” as they see fit…
perching_aix•5mo ago
People being able to measure it on their own != employers being given the right to require doing so and handing over the data. Matter of fact, you could outright ban employers from doing so. But then the topic of moan would become that regulations bad, and this would be then quickly portrayed as an industry backsetting obstacle.

Never a boring day.

Etheryte•5mo ago
This is one of those ideas that might sound good when you don't think about secondary effects, but is actually commonly accepted to be a bad idea in the medical community. Similar to white coat hypertension [0], measuring your stress can induce stress, whether that's worrying about whether you're in a good range, getting more stressed when you find out you're already stressed, or etc. This is why continuous monitoring is usually applied as little as reasonably possible, unless absolutely necessary like diabetes, ER, etc.

[0] https://en.wikipedia.org/wiki/White_coat_hypertension

NoPicklez•5mo ago
Smartwatches have been measuring all sorts from our bodies for a long time and whilst some people develop this type of thing, the majority have not. These watches have been monitoring stress in the form of HRV for many years now.
PaulHoule•5mo ago
A recent studied shows that Garmin watches like the one I have give HRV stress readings that don't correlate well to self-reports of stress

https://www.theguardian.com/technology/2025/aug/08/smartwatc...

The stress paradigm is probably the most holistic idea in medicine and I think any attempt to break it down to a number is reductivist.

m463•5mo ago
I have a garmin watch and my take is that stress is not really a spot reading.

However, I am certain that some really bad days I've had have shown very high stress on the watch across the day.

also relaxing can show low stress during a window (like sleep is low stress)

morkalork•5mo ago
I felt like I was trapped in a cycle of bad sleep -> stress -> worse sleep. And the two things that helped the most were exercising to burn of extra, nervous energy, and my fitbit breaking so I couldn't look at it and worry about how bad my sleep was.
heisenbit•5mo ago
> as little …

This is exactly the opposite of what which is written in the quoted wikipedia article:

> Ambulatory blood pressure monitoring and patient self-measurement using a home blood pressure monitoring device is being increasingly used to differentiate those with white coat hypertension or experiencing the white coat effect from those with chronic hypertension

Continuous monitoring is a viable workaround wrt. white coat symptoms. It is just a lot more effort and expensive.

Etheryte•5mo ago
Measuring your blood pressure at home is not continuous monitoring.
gessha•5mo ago
Continuously measuring blood pressure at home is continuous monitoring.
Etheryte•5mo ago
Unless you plan to sit at your desk all day and do nothing but press the button on your monitor, it isn't. These are two very different things.
curmudgeon22•5mo ago
There are devices called "holter monitors" that a person wears continuously and which measure your blood pressure frequently. I would call this continuous though it's more like every 15 minutes or whatever it's programmed for. It's all without your intervention. My ex bought one when they wanted more data about their high blood pressure.
PaulHoule•5mo ago
Because I fainted, I wore a holter monitor for a month that did not measure blood pressure but instead my EEG, uploading the data via the cellular network. My cardiologist said it measured about 1 million heatbeats in that time.
Etheryte•5mo ago
I'm well aware of this, but this is different from what we're discussing here. While Holters measure continuously, they don't give you continuous feedback. The general procedure is that the data is either gathered and downloaded or sent over network and the patient sees it only after the gathering is done.
amelius•5mo ago
It can be measured in a blind way.
brookst•5mo ago
This is what the kids call gatekeeping, not a whole lot different from the old “if the proles are allowed to read the religious texts they will get it wrong, better limit such things to priests.”

Yes, during the transition phase where information becomes available, some people will handle it badly, misinterpret, and generally be worse off.

But that’s a terrible reason to withhold knowledge, especially about peoples’ own bodies.

alphazard•5mo ago
There's no reason to think that continuous monitoring with a comfortable wearable would contribute to a white coat syndrome. The Wikipedia link that you cited actually says that at-home blood pressure readings are more reliable than those taken by a professional in a clinic because (it is believed) that the presence of another human administering a single test is what causes stress concerning the test. With the multiple, self-administered approach, there is no single test to fixate on, and no other human administering it.

> This is why continuous monitoring is usually applied as little as reasonably possible

The reason it is applied as little as possible is because it has been prohibitively expensive. For most things there is a benefit to sampling more often, and what sampling rate is adequate is entirely dependent on the maximum frequency that you need to observe. Another way of phrasing that is if it can change quickly, then you need to sample more often.

m463•5mo ago
I wonder why these kinds of arguments gain such wide acceptance.

specifically - measuring x has negative consequences, so don't measure x.

then at some point it becomes, don't bother measuring x ever.

Normally I hear abotu this like tests that can find cancer early, or full body MRIs.

I think these measures might actually be really good to establish a baseline and changes over time, or catch things early.

If the problem is that knowing leads to stress, maybe there could be a solution in the portrayal of the data. Maybe it could be "doctor, don't tell me unless there is a trend"

Doctors frequently give a disclaimer before ordering PSA tests, for example.

pixl97•5mo ago
>If the problem is that knowing leads to stress,

And who says information hazards don't exist. Gotta love how anxiety builds on anxiety.

cgannett•5mo ago
I suppose to mitigate that you could have that data not immediately viewable to the patient because seeing "stress line go up" would be pretty stressful and would skew the data anyway.
pstuart•5mo ago
Obligatory: https://en.wikipedia.org/wiki/Goodhart%27s_law
cheald•5mo ago
This would end up having effects like causing employers to discourage their employees from drinking coffee or exercising, both of which acutely raise cortisol levels.
grumpy-de-sre•5mo ago
I wonder if a similar technique could be used for Melatonin in saliva so that noninvasive circadian phase testing could be performed outside of the lab.

I'm convinced that if we actually looked at the circadian phase of the general population more closely we'd find A LOT of people with wonky clocks [1][2].

I've come to realize in recent months that I'm rocking a ~3h phase advance. Not terrible but it can sometimes make getting enough total sleep time challenging (bright light therapy in evenings really helps).

1. https://www.sydney.edu.au/news-opinion/news/2025/07/16/depre...

2. Circadian Genes, Rhythms, and the Biology of Bipolar Disorder - https://www.youtube.com/watch?v=eSL5hC8bzcU

avidiax•5mo ago
> I've come to realize in recent months that I'm rocking a ~3h phase advance.

How did you figure that out? And having a phase advance should just mean that you could shift your bedtime and waking time forward but still get a similar amount of sleep compared to someone with a "neutral" phase, whatever that means.

grumpy-de-sre•5mo ago
Shifting waking time forwards is straightforward but getting into bed early enough can be tough.

As for the phase shift, I've always had what I thought was maintenance insomnia but at some point I realized I always waking at exactly 4:30am. Going to bed early resolves the maintenance insomnia (also travelling eastward more than a few hours or so). My father and brother are the same.

I'd love to get a DLMO done to confirm. Thinking about experimenting with tracking core body temperature monitoring soon.

FWIW a 24h ambulatory blood pressure study actually showed a phase advanced nocturnal dip.

bradleyy•5mo ago
As a Type 1 Diabetic, I'd love to have a continuous version of this to pair with my Continuous Glucose Monitor, mainly because I'm convinced that glycogen output from the liver is what's causing a lot of variability, and would explain, e.g. early morning fasting increases in blood sugar.
ethan_smith•5mo ago
What you're describing is likely the dawn phenomenon - cortisol's morning spike triggers hepatic glucose production, and continuous monitoring could finally give diabetics actionable data to adjust treatment timing accordingly.
lenerdenator•5mo ago
I was in the study but my patch kept catching on fire when they put it on me.
strongpigeon•5mo ago
I think it’s worth emphasizing that this is a “mix and read” test (like a COVID test), not something you could integrate in a smartwatch for example.

Still cool nonetheless.

eximius•5mo ago
Oh I don't need this, I'm well aware of how stressed I am.