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Ask HN: How are researchers using AlphaFold in 2026?

1•jocho12•1m ago•0 comments

Running the "Reflections on Trusting Trust" Compiler

https://spawn-queue.acm.org/doi/10.1145/3786614
1•devooops•6m ago•0 comments

Watermark API – $0.01/image, 10x cheaper than Cloudinary

https://api-production-caa8.up.railway.app/docs
1•lembergs•8m ago•1 comments

Now send your marketing campaigns directly from ChatGPT

https://www.mail-o-mail.com/
1•avallark•11m ago•1 comments

Queueing Theory v2: DORA metrics, queue-of-queues, chi-alpha-beta-sigma notation

https://github.com/joelparkerhenderson/queueing-theory
1•jph•23m ago•0 comments

Show HN: Hibana – choreography-first protocol safety for Rust

https://hibanaworks.dev/
5•o8vm•25m ago•0 comments

Haniri: A live autonomous world where AI agents survive or collapse

https://www.haniri.com
1•donangrey•25m ago•1 comments

GPT-5.3-Codex System Card [pdf]

https://cdn.openai.com/pdf/23eca107-a9b1-4d2c-b156-7deb4fbc697c/GPT-5-3-Codex-System-Card-02.pdf
1•tosh•38m ago•0 comments

Atlas: Manage your database schema as code

https://github.com/ariga/atlas
1•quectophoton•41m ago•0 comments

Geist Pixel

https://vercel.com/blog/introducing-geist-pixel
2•helloplanets•44m ago•0 comments

Show HN: MCP to get latest dependency package and tool versions

https://github.com/MShekow/package-version-check-mcp
1•mshekow•52m ago•0 comments

The better you get at something, the harder it becomes to do

https://seekingtrust.substack.com/p/improving-at-writing-made-me-almost
2•FinnLobsien•53m ago•0 comments

Show HN: WP Float – Archive WordPress blogs to free static hosting

https://wpfloat.netlify.app/
1•zizoulegrande•55m ago•0 comments

Show HN: I Hacked My Family's Meal Planning with an App

https://mealjar.app
1•melvinzammit•55m ago•0 comments

Sony BMG copy protection rootkit scandal

https://en.wikipedia.org/wiki/Sony_BMG_copy_protection_rootkit_scandal
2•basilikum•58m ago•0 comments

The Future of Systems

https://novlabs.ai/mission/
2•tekbog•58m ago•1 comments

NASA now allowing astronauts to bring their smartphones on space missions

https://twitter.com/NASAAdmin/status/2019259382962307393
2•gbugniot•1h ago•0 comments

Claude Code Is the Inflection Point

https://newsletter.semianalysis.com/p/claude-code-is-the-inflection-point
3•throwaw12•1h ago•1 comments

Show HN: MicroClaw – Agentic AI Assistant for Telegram, Built in Rust

https://github.com/microclaw/microclaw
1•everettjf•1h ago•2 comments

Show HN: Omni-BLAS – 4x faster matrix multiplication via Monte Carlo sampling

https://github.com/AleatorAI/OMNI-BLAS
1•LowSpecEng•1h ago•1 comments

The AI-Ready Software Developer: Conclusion – Same Game, Different Dice

https://codemanship.wordpress.com/2026/01/05/the-ai-ready-software-developer-conclusion-same-game...
1•lifeisstillgood•1h ago•0 comments

AI Agent Automates Google Stock Analysis from Financial Reports

https://pardusai.org/view/54c6646b9e273bbe103b76256a91a7f30da624062a8a6eeb16febfe403efd078
1•JasonHEIN•1h ago•0 comments

Voxtral Realtime 4B Pure C Implementation

https://github.com/antirez/voxtral.c
2•andreabat•1h ago•1 comments

I Was Trapped in Chinese Mafia Crypto Slavery [video]

https://www.youtube.com/watch?v=zOcNaWmmn0A
2•mgh2•1h ago•1 comments

U.S. CBP Reported Employee Arrests (FY2020 – FYTD)

https://www.cbp.gov/newsroom/stats/reported-employee-arrests
1•ludicrousdispla•1h ago•0 comments

Show HN: I built a free UCP checker – see if AI agents can find your store

https://ucphub.ai/ucp-store-check/
2•vladeta•1h ago•1 comments

Show HN: SVGV – A Real-Time Vector Video Format for Budget Hardware

https://github.com/thealidev/VectorVision-SVGV
1•thealidev•1h ago•0 comments

Study of 150 developers shows AI generated code no harder to maintain long term

https://www.youtube.com/watch?v=b9EbCb5A408
2•lifeisstillgood•1h ago•0 comments

Spotify now requires premium accounts for developer mode API access

https://www.neowin.net/news/spotify-now-requires-premium-accounts-for-developer-mode-api-access/
2•bundie•1h ago•0 comments

When Albert Einstein Moved to Princeton

https://twitter.com/Math_files/status/2020017485815456224
1•keepamovin•1h ago•0 comments
Open in hackernews

Ask HN: How would you build second brain in the AI era?

9•divan•6mo ago
A lot of people use 'second brain' software and are now trying to connect/integrate them with LLMs.

But if you were starting with a new 'second brain' from scratch, how would you do it, given the current state (and trends) in AI/LLMs?

Comments

nextos•6mo ago
Less structure? I think links are less necessary. It's a bit like using email when search is cheap, you don't need to rely on tags if you don't want to.

I have a fairly large set of notes written in Org, and I never bothered with internal links. Ripgrep search was always enough for me to make connections.

With local LLMs, it's even better. gptel makes it really easy to add notes as context.

alganet•6mo ago
I wouldn't. It's a vulnerability to have your data somewhere else.

People know this. The first actual "second brain" of some sorts is likely to be unwilling, made by someone else trying to capture the thoughts of a subject. It is also likely that it will fail (given the fact we don't know shit about how brains work).

runjake•6mo ago
I think it depends on what the person does. I'm a knowledge worker, so this works for me. Other people may see little use in notes.

A pool of well-structured notes and knowledge with an "AI technologies du jour" trained on it.

I currently use Obsidian and some tools for this, although it's not completely frictionless yet.

mradek•6mo ago
I would much rather just contribute to the AI directly. I am kind of tired having to use so many different tools. I don’t even want to login or authenticate with dozens or hundreds of them.

Why won’t these companies completely transform how we work/vibe by having everything go through the chat/voice ui? It should just work, for the end user.

I’d love to be an agnostic business analyst for OpenAI or Anthropic. Used to be a business analyst and I loved understanding as much about an industry or domain and then working with stakeholders to come up with solutions.

Imagine if there were teams of business analysts internally at these companies to build out that super app.. supply chain (procurement, resolutions, dispatch), partner management, customer support, calling someone video or voice, all my documents, everything I keep basically. I want to work and communicate with other people over it. It should just work. All work is communication between people right?

eimrine•6mo ago
I would like to give him a curated set of books, then have a discussion.

Also I would like to share all my life with some kind of LLM but I really want that data to be just for me.