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Ask HN: How are researchers using AlphaFold in 2026?

1•jocho12•2m ago•0 comments

Running the "Reflections on Trusting Trust" Compiler

https://spawn-queue.acm.org/doi/10.1145/3786614
1•devooops•7m ago•0 comments

Watermark API – $0.01/image, 10x cheaper than Cloudinary

https://api-production-caa8.up.railway.app/docs
1•lembergs•8m ago•1 comments

Now send your marketing campaigns directly from ChatGPT

https://www.mail-o-mail.com/
1•avallark•12m ago•1 comments

Queueing Theory v2: DORA metrics, queue-of-queues, chi-alpha-beta-sigma notation

https://github.com/joelparkerhenderson/queueing-theory
1•jph•24m ago•0 comments

Show HN: Hibana – choreography-first protocol safety for Rust

https://hibanaworks.dev/
5•o8vm•26m ago•0 comments

Haniri: A live autonomous world where AI agents survive or collapse

https://www.haniri.com
1•donangrey•26m ago•1 comments

GPT-5.3-Codex System Card [pdf]

https://cdn.openai.com/pdf/23eca107-a9b1-4d2c-b156-7deb4fbc697c/GPT-5-3-Codex-System-Card-02.pdf
1•tosh•39m ago•0 comments

Atlas: Manage your database schema as code

https://github.com/ariga/atlas
1•quectophoton•42m ago•0 comments

Geist Pixel

https://vercel.com/blog/introducing-geist-pixel
2•helloplanets•45m ago•0 comments

Show HN: MCP to get latest dependency package and tool versions

https://github.com/MShekow/package-version-check-mcp
1•mshekow•53m ago•0 comments

The better you get at something, the harder it becomes to do

https://seekingtrust.substack.com/p/improving-at-writing-made-me-almost
2•FinnLobsien•54m ago•0 comments

Show HN: WP Float – Archive WordPress blogs to free static hosting

https://wpfloat.netlify.app/
1•zizoulegrande•56m ago•0 comments

Show HN: I Hacked My Family's Meal Planning with an App

https://mealjar.app
1•melvinzammit•56m ago•0 comments

Sony BMG copy protection rootkit scandal

https://en.wikipedia.org/wiki/Sony_BMG_copy_protection_rootkit_scandal
2•basilikum•59m ago•0 comments

The Future of Systems

https://novlabs.ai/mission/
2•tekbog•59m ago•1 comments

NASA now allowing astronauts to bring their smartphones on space missions

https://twitter.com/NASAAdmin/status/2019259382962307393
2•gbugniot•1h ago•0 comments

Claude Code Is the Inflection Point

https://newsletter.semianalysis.com/p/claude-code-is-the-inflection-point
3•throwaw12•1h ago•1 comments

Show HN: MicroClaw – Agentic AI Assistant for Telegram, Built in Rust

https://github.com/microclaw/microclaw
1•everettjf•1h ago•2 comments

Show HN: Omni-BLAS – 4x faster matrix multiplication via Monte Carlo sampling

https://github.com/AleatorAI/OMNI-BLAS
1•LowSpecEng•1h ago•1 comments

The AI-Ready Software Developer: Conclusion – Same Game, Different Dice

https://codemanship.wordpress.com/2026/01/05/the-ai-ready-software-developer-conclusion-same-game...
1•lifeisstillgood•1h ago•0 comments

AI Agent Automates Google Stock Analysis from Financial Reports

https://pardusai.org/view/54c6646b9e273bbe103b76256a91a7f30da624062a8a6eeb16febfe403efd078
1•JasonHEIN•1h ago•0 comments

Voxtral Realtime 4B Pure C Implementation

https://github.com/antirez/voxtral.c
2•andreabat•1h ago•1 comments

I Was Trapped in Chinese Mafia Crypto Slavery [video]

https://www.youtube.com/watch?v=zOcNaWmmn0A
2•mgh2•1h ago•1 comments

U.S. CBP Reported Employee Arrests (FY2020 – FYTD)

https://www.cbp.gov/newsroom/stats/reported-employee-arrests
1•ludicrousdispla•1h ago•0 comments

Show HN: I built a free UCP checker – see if AI agents can find your store

https://ucphub.ai/ucp-store-check/
2•vladeta•1h ago•1 comments

Show HN: SVGV – A Real-Time Vector Video Format for Budget Hardware

https://github.com/thealidev/VectorVision-SVGV
1•thealidev•1h ago•0 comments

Study of 150 developers shows AI generated code no harder to maintain long term

https://www.youtube.com/watch?v=b9EbCb5A408
2•lifeisstillgood•1h ago•0 comments

Spotify now requires premium accounts for developer mode API access

https://www.neowin.net/news/spotify-now-requires-premium-accounts-for-developer-mode-api-access/
2•bundie•1h ago•0 comments

When Albert Einstein Moved to Princeton

https://twitter.com/Math_files/status/2020017485815456224
1•keepamovin•1h ago•0 comments
Open in hackernews

Sunlight-activated material turns PFAS in water into harmless fluoride

https://phys.org/news/2025-08-sunlight-material-pfas-harmless-fluoride.html
79•bookofjoe•6mo ago

Comments

nick238•6mo ago
The Materials Science Gameplay Loop:

1. Invent fantastic new material that does a heretofore novel reaction or one with improved performance (chemical, photovoltaic, etc.)

2. Do #1 without lead, cadmium, mercury, or arsenic.

SociallyAwesomeAwkwardPenguinMeme("Turns PFAS to fluoride", "Contains Cadmium")

momoschili•6mo ago
3. Do #2 without platinum, palladium, rhodium, ruthenium to make it economically viable
3eb7988a1663•6mo ago
Is that much of a problem for a catalyst? Presumably you do not need many of these: at water treatment plants and at the waste-stream for manufacturing processes which emit PFAS. You might not be able to justify the expense inside your home water purification system, but it could still be cost effective for large scale installations.
momoschili•6mo ago
it depends on the scale and the required amounts. If having a limited amount of catalyst wasn't such a big problem I suspect hydrogen power would have been much more economically viable.
ambicapter•6mo ago
I thought the point of catalysts was that they don't get used up in the reaction they promote.
djtango•6mo ago
The real world is messy - catalysts gradually need replacement over time in non lab conditions

https://en.m.wikipedia.org/wiki/Catalyst_poisoning

lazide•6mo ago
The issue with hydrogen is the source of hydrogen.
throwup238•6mo ago
You would need a lot of catalyst because the water infrastructure to supply several hundred million people in the US is massive, let alone the rest of the world.

The problem with those catalysts is that the latter two are minor components of platinum and copper/nickel ores and despite how expensive they are, the extraction is only economically viable as part of other mining. Their supply can only grow as much as platinum extraction allows and demand is already pretty significant with environmental regulations often necessitating their use. Any more demand for them will cause their prices to rise dramatically and its a long way before they become profitable enough to mine on their own (flooding the platinum market in the process which has much higher yields from the ores).

SoftTalker•6mo ago
Activated carbon filtering removes up to about 75% of PFAS. Reverse-osmosis removes almost all.

Doesn't get rid of them, to be clear. It would still be better if a way could be found to chemically (and cheaply) convert them to something less harmful.

N2yhWNXQN3k9•6mo ago
> Activated carbon filtering removes up to about 75%

Seems like the limitation must be more than reducing concentrations in fluid? Otherwise you'd just do multiple passes?

BugsJustFindMe•6mo ago
> Activated carbon filtering removes up to about 75% of PFAS

Common inexpensive non-RO filter systems come with independent test results showing 99% removal of PFOA/PFOS (see e.g https://www.brondell.com/content/UC300_Coral_PDS.pdf). Do we have reason to believe that other PFAS don't filter as easily?

SoftTalker•6mo ago
AIHI the shorter PFAS molecules are not captured as effectively by activated carbon.
momoschili•6mo ago
Yes, the key here is the degradation of the forever chemical, not the removal. Removal itself doesn't really change the environmental scale of it
KennyBlanken•6mo ago
Alternative path, like with General Electric:

Invent seemingly fantastic new material. Discover it is harmful to humans and wildlife, accumulates in groundwater, etc. Bury that discovery.

Get caught after decades of wild profits, the occasional secret settlement, and spend a decade more fighting legal action before finally running out of appeals or the writing is on the wall, and accept it and pay out.

Start selling water filtration systems, thus profiting off people dealing with your pollution.

This is what I find so frustrating about "the fight against cancer." I'm convinced cancer is so prevalent because corporations are poisoning the shit out of our environment, and thus our water supply, our food, our air. Because we're not equipped with timestamping chemical detection systems, it's difficult to identify the exposure that caused it or increased the person's risk, so industry gets a "freebie" death nobody can pin to them. As long as the chemical isn't toxic enough to be obvious - the companies get away scott free, despite an extensive history of the chemical industry time and time again coming up with some major novel chemical that comes to be used all over society and turns out to be toxic.

Bill Moyers once submitted his blood to a lab and asked them to test for everything they could identify in terms of industrial chemicals, pesticides, etc. The blood was a veritable toxic soup (and some of the control sample containers were contaminated from the supplier, showing how pervasive the toxins are): https://www.pbs.org/tradesecrets/problem/popup_bb_02.html

You don't "fight cancer" doing walks and charity balls and cute-kid-starts-fundraiser-because-friend-dies-from-leukemia. You fight cancer by addressing the toxins being pumped into us in the name of profit and "bettering society", allowed to get away with it because of how difficult it is to show any particular chemical directly caused the cancer.

anonymars•6mo ago
If only the vaccine-autism energy could be directed in the right place

PS not to diminish GE's game but they certainly weren't the only player. This one always stuck with me: https://en.wikipedia.org/wiki/Minamata_disease#Wastewater_tr...

exogenousdata•6mo ago
Sadly the goal of vaccine-autism energy has largely become to destabilize western nation states. But I share the sentiment!
prophesi•6mo ago
It's a bit disheartening to see that the Bill Moyer's documentary came out in 2001, and not much has changed to keep these corporations accountable.
barbazoo•6mo ago
Growth and consumption under all circumstances. And we’re fuelling it with our personal behavior.
nraynaud•6mo ago
I'm a bit confused, are they suggesting that a cadnium coumpound to treat PFAS is a done deal?
pxeger1•6mo ago
Ignoring the cadmium problem, is fluoride really harmless? I don't know what concentration of fluoride you'd end up with from converting typical PFAS pollution, but if you get enough fluoride it is acutely poisonous, which might be worse than the carcinogenic PFAS. (Likewise, it might be worse for the environment)
nick238•6mo ago
Fluoride doesn't bio-accumulate like PFAS do, which has a strong affinity for proteins and fats in organisms. Constantly drinking water with 0.5-1 ppm fluoride may cause minor side effects like mild dental fluorosis, but you'll excrete almost all the excess as it's very water soluble. Drink water with any PFAS, and your body will strongly hold on to it all.
formerly_proven•6mo ago
"0.5-1 ppm" covers what's considered the optimum level of fluoride in drinking water, so I doubt you'd get dental fluorosis from that. Coincidentally, if you calculate the equivalent dose that you'd give babies (via dissolved vitamin D + fluoride tablets), you also end up at about 0.3-0.5ppm.
bawolff•6mo ago
Everything is toxic at a certain conentration, but as far as i know PFAS is a million times more toxic than flouride.

According to the EPA safe level for flouride for drinking water is up to 4 mg/L. The epa level for PFOS is 0.000004 mg/L, literally a million times lower.

sitkack•6mo ago
I thought the EPA was deregulating everything except flouride which it was going to deem a poison.
exogenousdata•6mo ago
Fair point. We should probably have some way to refer to US gov’t funded scientific orgs & their research/recommendations before vs after the 2nd Trump Administration.
quinndexter•6mo ago
Pre/post 47.
ChrisMarshallNY•6mo ago
Fluoride?!!

Isn't that supposed to be some kind of demonic juice?

Why else is the government so intent on making sure that there's none in our water? I'm sure that they would much rather have the PFAS, produced by their nice, generous, industrialist bros.

sitkack•6mo ago
And PFAS are used heavily in the manufacturing of microchips (photoresist and etching).
ChrisMarshallNY•6mo ago
The PFAS are the mellowest chemicals they use.

I think they use this stuff: https://www.science.org/content/blog-post/sand-won-t-save-yo...

f_devd•6mo ago
At least that will self-decompose, reactive chemicals aren't usually a problem