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Interop 2025: A Year of Convergence

https://webkit.org/blog/17808/interop-2025-review/
1•ksec•9m ago•0 comments

JobArena – Human Intuition vs. Artificial Intelligence

https://www.jobarena.ai/
1•84634E1A607A•13m ago•0 comments

Concept Artists Say Generative AI References Only Make Their Jobs Harder

https://thisweekinvideogames.com/feature/concept-artists-in-games-say-generative-ai-references-on...
1•KittenInABox•17m ago•0 comments

Show HN: PaySentry – Open-source control plane for AI agent payments

https://github.com/mkmkkkkk/paysentry
1•mkyang•19m ago•0 comments

Show HN: Moli P2P – An ephemeral, serverless image gallery (Rust and WebRTC)

https://moli-green.is/
1•ShinyaKoyano•28m ago•0 comments

The Crumbling Workflow Moat: Aggregation Theory's Final Chapter

https://twitter.com/nicbstme/status/2019149771706102022
1•SubiculumCode•33m ago•0 comments

Pax Historia – User and AI powered gaming platform

https://www.ycombinator.com/launches/PMu-pax-historia-user-ai-powered-gaming-platform
2•Osiris30•33m ago•0 comments

Show HN: I built a RAG engine to search Singaporean laws

https://github.com/adityaprasad-sudo/Explore-Singapore
1•ambitious_potat•39m ago•0 comments

Scams, Fraud, and Fake Apps: How to Protect Your Money in a Mobile-First Economy

https://blog.afrowallet.co/en_GB/tiers-app/scams-fraud-and-fake-apps-in-africa
1•jonatask•39m ago•0 comments

Porting Doom to My WebAssembly VM

https://irreducible.io/blog/porting-doom-to-wasm/
1•irreducible•40m ago•0 comments

Cognitive Style and Visual Attention in Multimodal Museum Exhibitions

https://www.mdpi.com/2075-5309/15/16/2968
1•rbanffy•41m ago•0 comments

Full-Blown Cross-Assembler in a Bash Script

https://hackaday.com/2026/02/06/full-blown-cross-assembler-in-a-bash-script/
1•grajmanu•46m ago•0 comments

Logic Puzzles: Why the Liar Is the Helpful One

https://blog.szczepan.org/blog/knights-and-knaves/
1•wasabi991011•58m ago•0 comments

Optical Combs Help Radio Telescopes Work Together

https://hackaday.com/2026/02/03/optical-combs-help-radio-telescopes-work-together/
2•toomuchtodo•1h ago•1 comments

Show HN: Myanon – fast, deterministic MySQL dump anonymizer

https://github.com/ppomes/myanon
1•pierrepomes•1h ago•0 comments

The Tao of Programming

http://www.canonical.org/~kragen/tao-of-programming.html
2•alexjplant•1h ago•0 comments

Forcing Rust: How Big Tech Lobbied the Government into a Language Mandate

https://medium.com/@ognian.milanov/forcing-rust-how-big-tech-lobbied-the-government-into-a-langua...
3•akagusu•1h ago•0 comments

PanelBench: We evaluated Cursor's Visual Editor on 89 test cases. 43 fail

https://www.tryinspector.com/blog/code-first-design-tools
2•quentinrl•1h ago•2 comments

Can You Draw Every Flag in PowerPoint? (Part 2) [video]

https://www.youtube.com/watch?v=BztF7MODsKI
1•fgclue•1h ago•0 comments

Show HN: MCP-baepsae – MCP server for iOS Simulator automation

https://github.com/oozoofrog/mcp-baepsae
1•oozoofrog•1h ago•0 comments

Make Trust Irrelevant: A Gamer's Take on Agentic AI Safety

https://github.com/Deso-PK/make-trust-irrelevant
7•DesoPK•1h ago•4 comments

Show HN: Sem – Semantic diffs and patches for Git

https://ataraxy-labs.github.io/sem/
1•rs545837•1h ago•1 comments

Hello world does not compile

https://github.com/anthropics/claudes-c-compiler/issues/1
35•mfiguiere•1h ago•20 comments

Show HN: ZigZag – A Bubble Tea-Inspired TUI Framework for Zig

https://github.com/meszmate/zigzag
3•meszmate•1h ago•0 comments

Metaphor+Metonymy: "To love that well which thou must leave ere long"(Sonnet73)

https://www.huckgutman.com/blog-1/shakespeare-sonnet-73
1•gsf_emergency_6•1h ago•0 comments

Show HN: Django N+1 Queries Checker

https://github.com/richardhapb/django-check
1•richardhapb•1h ago•1 comments

Emacs-tramp-RPC: High-performance TRAMP back end using JSON-RPC instead of shell

https://github.com/ArthurHeymans/emacs-tramp-rpc
1•todsacerdoti•1h ago•0 comments

Protocol Validation with Affine MPST in Rust

https://hibanaworks.dev
1•o8vm•2h ago•1 comments

Female Asian Elephant Calf Born at the Smithsonian National Zoo

https://www.si.edu/newsdesk/releases/female-asian-elephant-calf-born-smithsonians-national-zoo-an...
5•gmays•2h ago•1 comments

Show HN: Zest – A hands-on simulator for Staff+ system design scenarios

https://staff-engineering-simulator-880284904082.us-west1.run.app/
1•chanip0114•2h ago•1 comments
Open in hackernews

Why Hasn't Medical Science Cured Chronic Headaches?

https://www.newyorker.com/magazine/2025/08/18/the-headache-tom-zeller-jr-book-review
18•fortran77•5mo ago

Comments

theLegionWithin•5mo ago
the Aspirin lobby won't allow that (presumably, article is paywalled, so who knows)
cluckindan•5mo ago
Because psilocybin cannot be patented.

https://www.cambridge.org/core/journals/european-psychiatry/...

thejazzman•5mo ago
i don't need to read that article to tell you it absolutely unquestionably does not resolve chronic headaches, not even for a day.

for someone, sometimes? sure, probably. even placebos do that.

there are a bajillion of causes of headaches. there is no one solution. that's the problem.

cluckindan•5mo ago
”The greatest benefit reported was for psilocybin taken during a remission period, with the average length of that remission period between headaches extending for 91% of participants.”

Maybe you actually need to read the article.

kelseyfrog•5mo ago
I don't get it. The prevalence of headaches must mean some doctors also get headaches. How do they reconcile their symptoms with their practice?

Same goes for women's health. Surely some typically painful routine procedures are experienced by the very doctors that perform them. Again, how do they reconcile their experience with how they practice?

viraptor•5mo ago
> How do they reconcile their symptoms with their practice?

What do you mean by that?

kelseyfrog•5mo ago
The article describes this:

Patients seeking solutions often experience frustration and desperation. They visit neurologists, anesthesiologists, pain-management specialists, alternative healers, and online chat groups, trying to find explanations and relief.

Given the base-rate, surely some doctors must also experience these maladies themselves. How do they resolve the apparent contradiction of presumably their own frustration and desperation as a patient and while also being in some way the creator of it as a doctor?

root_axis•5mo ago
> How do they resolve the apparent contradiction of presumably their own frustration and desperation as a patient and while also being in some way the creator of it as a doctor?

Those are typically different people, so there is no contradiction.

kelseyfrog•5mo ago
I understand they are different people. But, you would agree sometimes doctors have headaches where they are then are a patient treated by another doctor, right?

How would that person understand the contradiction of sometimes being in a role where they dismiss patients, but also sometimes being in the role of the patient where they are being dismissed?

elliotto•5mo ago
I've thought about this problem a lot too.

I've wondered if it comes down to a game theory result where if you have x amount of time to distribute amongst y problems, there's more net social utility in applying a simple solution to everyone, and accepting that difficult problems will be missed. Versus spending detailed time on each problem, and as a result solving fewer problems but better.

Of course, when money comes into play, it seems as though you're going to be financially required to rush everyone through the door in 15 minutes, or else your business will lose to someone who adopts this strategy. Leaving anyone with a complex problem dead.

I spend a lot of time on migraine and pain subreddits and there is an air of deference to the medical authority to know what to do. But if your case is complex, you just can't fit into the simple flow chart, and need to advocate and problem solve for yourself. Which leads people into the path of pseudoscience and exploitation.

viraptor•5mo ago
This is not uncommon. There's lots of issues where there are no easy answer and even if you know most answers, the solutions are "there is ~20% chance this will help, if not there is ~15% chance this will help, ... etc.". And that's assuming you can identify the real problem not masking as something else. Dealing with the uncertainty is part of the job. Ideally you'd want the doctor to explain it to the patients too. But I wouldn't say they create the frustration as such. The frustration is that nobody know better answers.
allturtles•5mo ago
> I don't get it. The prevalence of headaches must mean some doctors also get headaches. How do they reconcile their symptoms with their practice?

I don't get what you or the OP expects them to do about it. There is no secret cure for migraines they are hiding from the rest of us.

kelseyfrog•5mo ago
That's good because I wasn't asking them to do anything about it. I was asking to understand an apparent emotional-empathy contradiction. I don't think you would be able to answer it unless you had personal experience being in that situation.
viraptor•5mo ago
https://archive.is/20250813193253/https://www.newyorker.com/...
ElijahLynn•5mo ago
Pain Brain Film covers the new pain reprocessing therapy which might be linked to untreatable headaches.
elliotto•5mo ago
The author is a New yorker columnist, and seems to be a practicing / ex-practicing doctor. They talk about their experience with their various doctors and being passed around different medications with various side effects, to some degree of success. Despite all their expertise and expense, they still cannot find a root cause (which may not exist at all), and struggle to find a medication protocol that works for them.

If you really want a bad trip, head over to the r/migraine and r/chronicpain subreddits. These subreddits are full of people, with none of the resources or experiences as the author, betrayed entirely by the medical system which does not serve them, and condemned to chronic pain. The complexity and range of headache and migraine causes does not lend itself well to a 15 minute GP appointment every few months, and without the technical expertise these people turn to alternative medicine, online pseudoscience, and opiates.

tracker1•5mo ago
I can't speak for others, but I've found my severe headaches are sometimes migrains, other times sinus headaches, retina pain, and/or iris pain. Most of the time, a couple over the counter "migraine" pills helps if I catch it early, most commonly starts in the morning as I wake up. If that doesn't work, in a couple hours a prescribed migraine pill... if I notice my irises are pin hole sized (as closed as can be), I have dilation drops that help. If that doesn't cut it, I'll take a cannabis gummy and just try to sleep until it goes away.

A couple times a year, it lasts for a day or more. That's when it really sucks. I keep on top of taking mucus relief and allergy pills, which keeps down the sinus headaches... but I'm never quite sure what it is, as it's all just sever pain inside my head. Often coming with nausea, severe pain, dizziness and sometimes panic attacks.

I also have chronic back and hip pain as well. I don't like opiates at all, they tend to come with excessive nausea.

fraserphysics•5mo ago
I started getting migraines in the 1960s. Thanks for the link.

While a cup of coffee often helped me feel better in years past, I've found eliminating coffee from my diet has reduced my headache frequency. Triptans help when I get the occasional headache now.

I was disappointed that the article didn't talk about the variety of migraine manifestations. Some of the manifestations can be confused with transient ischemic attacks.

aredox•5mo ago
Decaffinated coffee is getting better and better every year; that could be a way for you to keep enjoying its benefits (mostly unrelated to caffeine) without the drawbacks.
general1726•5mo ago
Because there are no pain receptors in the brain, so if you have headache, you are just hallucinating your own pain through some positive feedback mechanism.
dragonwriter•5mo ago
Er, no. There are no pain receptors in the brain, but there are pain receptors in the head (particularly, the meninges, periosteum, and scalp), and those are the receptors which produce headaches.
general1726•5mo ago
I don't think that you had headache before, because that you would know that would hurts is not a scalp.
dragonwriter•5mo ago
I’ve had many headaches, some of which respond exactly like you’d expect if the source of pain was receptors in the scalp, others of which do not.

The meninges and periosteum, which I mentioned also have pain receptors which can be involved in headaches, are very much not the same thing as the scalp.

The idea that the brain doesn't have pain receptors implies that headaches are just hallucinated pain is just completely nonsense.

1718627440•5mo ago
In my understanding of the term pain in the scalp is not a headache, that would be pain in the scalp.
metalman•5mo ago
BLARG! there is a very very good chance that there are other mechanisms for triggering pain responses, like unnatural chemicals, such as concentrated ethenol or diesel fuel, photo copier fluid, etc, that can cross the blood brain barier, causing intense pain in many cases, but have little effect if applied topicaly. on the flip side, one rather interesting thing about pain, is that it impossible to trigger pain from a memory, but then there are cases of symptoms of phantom pain in lost limbs, so I feel strongly that there will be new knowledge soon about pain, especialy as there a number of promising non opiod pain relievers that use completly different pathways to block pain.