frontpage.
newsnewestaskshowjobs

Made with ♥ by @iamnishanth

Open Source @Github

Open in hackernews

Study: Lp(a) testing would save both lives and dollars

https://www.sciencedirect.com/science/article/pii/S0021915025013450
1•brandonb•2h ago

Comments

brandonb•2h ago
In medicine, there's often tradeoff between health and cost. GLP-1s are an obvious example, costing $10,000 per year but saving lives.

This study shows an exception to that rule -- testing Lp(a), the strongest hereditary biomarker of heart disease risk.

This study simulated the effects of wide-spread Lp(a) testing on a sample of 10,000 patients in two countries (UK and Australia). They found 1,807 people would have had modified treatment, gaining 217-255 quality-adjusted life years. (Quality-adjusted life years are used by the NHS in the UK to make policy decisions.)

Furthermore, they found there would be an overall cost savings, since Lp(a) testing itself is cheap and it prevents heart attacks and strokes (which are expensive to treat).

It's really rare in medicine to find an "obvious win" like this.

An Update on Pytype

https://github.com/google/pytype
4•mxmlnkn•3m ago•0 comments

Is the A.I. Sell-Off the Start of Something Bigger?

https://www.nytimes.com/2025/08/20/business/dealbook/ai-dip-blip-palantir-nvidia.html
1•voxadam•3m ago•1 comments

How harmful is blue light for sleep?

https://www.nytimes.com/2025/08/17/well/health-effects-blue-light-screen-use.html
1•bookofjoe•6m ago•1 comments

US Health Secretary Ends Decades of Research into Environmental Causes of Autism

https://www.propublica.org/article/rfk-jr-autism-environment-research-funding
1•klipt•7m ago•0 comments

CSS line-height unit 1h

https://caniuse.com/mdn-css_types_length_lh
1•Brajeshwar•7m ago•0 comments

American Millennials Are Dying at an Alarming Rate

https://slate.com/technology/2025/08/millennials-gen-z-death-rates-america-high.html
1•damien•7m ago•0 comments

The Four Stages of Objective-Smalltalk

https://blog.metaobject.com/2019/12/the-4-stages-of-objective-smalltalk.html
1•thunderbong•8m ago•0 comments

L2AW Theorem

https://law-theorem.com/
1•avinassh•9m ago•0 comments

The Pragmatic Engineer 2025 Survey: What's in your tech stack? Part 2

https://newsletter.pragmaticengineer.com/p/the-pragmatic-engineer-2025-survey-part-2
1•CharlesW•11m ago•0 comments

Dagger and opencode and agnostic agents and SSH app = most portable dev kit

3•epuerta99•13m ago•0 comments

Crash Cows

https://beza1e1.tuxen.de/lore/crash_cows.html
4•indrora•14m ago•0 comments

What went wrong with Social Media?

https://arun626588.substack.com/p/what-went-wrong-with-social-media
1•rohannihalani•14m ago•0 comments

Openwetware.org shut down due to funding

https://openwetware.org/
1•eldenring•14m ago•0 comments

James Webb Space Telescope runs an extended version of JavaScript [pdf]

https://www.stsci.edu/~idash/pub/dashevsky0607rcsgso.pdf
2•homebrewer•15m ago•0 comments

Travel eSIMs route traffic over Chinese and undisclosed networks: study

https://www.itnews.com.au/news/travel-esims-secretly-route-traffic-over-chinese-and-undisclosed-networks-study-619659
3•taubek•15m ago•0 comments

Cool or Hard

https://belief.horse/notes/cool-or-hard/
1•doctorhandshake•16m ago•0 comments

For decades, sleep has been passive

https://xcancel.com/dwdavison/status/1957972610202960005#m
1•palmfacehn•17m ago•0 comments

Notes on Image Generation with GPT-4.1

https://taoofmac.com/space/notes/2025/07/20/1230
1•rcarmo•18m ago•0 comments

The reason the West is warmongering against China

https://www.aljazeera.com/opinions/2025/8/3/the-real-reason-the-west-is-warmongering-against-china
3•Qem•18m ago•0 comments

Integrating Jenkins with AEM Deployments

https://aemslate.com/integrating-jenkins-with-aem-deployments
1•a-blank-slate•19m ago•0 comments

Disk Sampling on the Sphere

https://observablehq.com/@jrus/spheredisksample
3•jacobolus•19m ago•0 comments

Just Write

https://www.moll.dev/notes/justwrite/
3•mooreds•19m ago•0 comments

A proposal for inline LLM instructions in HTML based on llms.txt

https://vercel.com/blog/a-proposal-for-inline-llm-instructions-in-html
3•brycewray•20m ago•0 comments

Hx-optimistic: Declarative optimistic updates for Htmx

https://www.lorenstew.art/blog/hx-optimistic/
1•lorenstewart•21m ago•0 comments

Show HN: Yellhorn – MCP server to help coding agents 1-shot long tasks

https://github.com/msnidal/yellhorn-mcp
1•sravanjayanthi•26m ago•1 comments

REITs Buying Tranches of Single-Family Homes (2024)

https://finance.yahoo.com/news/other-side-hedge-funds-reits-180055854.html
3•danielam•27m ago•0 comments

ComputerRL: Scaling Reinforcement Learning for Computer Use Agents

https://arxiv.org/abs/2508.14040
1•cjbarber•29m ago•0 comments

Processing 24T tokens for LLM training with 0 crashes (what made it possible)

https://www.daft.ai/blog/how-essential-ai-built-essential-web-v1-with-daft
1•DISCURSIVE•32m ago•0 comments

Digg.com Is Back

https://www.digg.com/
47•thatgerhard•32m ago•34 comments

Show HN: A new JavaScript runtime for writing high-performance web apps in Rust

https://www.npmjs.com/package/brahma-firelight
1•StellaMary•33m ago•1 comments