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Study: Lp(a) testing would save both lives and dollars

https://www.sciencedirect.com/science/article/pii/S0021915025013450
1•brandonb•5mo ago

Comments

brandonb•5mo ago
In medicine, there's often tradeoff between health and cost. GLP-1s are an obvious example, costing $10,000 per year but saving lives.

This study shows an exception to that rule -- testing Lp(a), the strongest hereditary biomarker of heart disease risk.

This study simulated the effects of wide-spread Lp(a) testing on a sample of 10,000 patients in two countries (UK and Australia). They found 1,807 people would have had modified treatment, gaining 217-255 quality-adjusted life years. (Quality-adjusted life years are used by the NHS in the UK to make policy decisions.)

Furthermore, they found there would be an overall cost savings, since Lp(a) testing itself is cheap and it prevents heart attacks and strokes (which are expensive to treat).

It's really rare in medicine to find an "obvious win" like this.

Was going to share my work

1•hiddenarchitect•2m ago•0 comments

Pitchfork: A devilishly good process manager for developers

https://pitchfork.jdx.dev/
1•ahamez•2m ago•0 comments

You Are Here

https://brooker.co.za/blog/2026/02/07/you-are-here.html
2•mltvc•7m ago•0 comments

Why social apps need to become proactive, not reactive

https://www.heyflare.app/blog/from-reactive-to-proactive-how-ai-agents-will-reshape-social-apps
1•JoanMDuarte•7m ago•1 comments

How patient are AI scrapers, anyway? – Random Thoughts

https://lars.ingebrigtsen.no/2026/02/07/how-patient-are-ai-scrapers-anyway/
1•samtrack2019•8m ago•0 comments

Vouch: A contributor trust management system

https://github.com/mitchellh/vouch
1•SchwKatze•8m ago•0 comments

I built a terminal monitoring app and custom firmware for a clock with Claude

https://duggan.ie/posts/i-built-a-terminal-monitoring-app-and-custom-firmware-for-a-desktop-clock...
1•duggan•9m ago•0 comments

Tiny C Compiler

https://bellard.org/tcc/
1•guerrilla•10m ago•0 comments

Y Combinator Founder Organizes 'March for Billionaires'

https://mlq.ai/news/ai-startup-founder-organizes-march-for-billionaires-protest-against-californi...
1•hidden80•11m ago•1 comments

Ask HN: Need feedback on the idea I'm working on

1•Yogender78•11m ago•0 comments

OpenClaw Addresses Security Risks

https://thebiggish.com/news/openclaw-s-security-flaws-expose-enterprise-risk-22-of-deployments-un...
1•vedantnair•12m ago•0 comments

Apple finalizes Gemini / Siri deal

https://www.engadget.com/ai/apple-reportedly-plans-to-reveal-its-gemini-powered-siri-in-february-...
1•vedantnair•12m ago•0 comments

Italy Railways Sabotaged

https://www.bbc.co.uk/news/articles/czr4rx04xjpo
3•vedantnair•13m ago•0 comments

Emacs-tramp-RPC: high-performance TRAMP back end using MsgPack-RPC

https://github.com/ArthurHeymans/emacs-tramp-rpc
1•fanf2•14m ago•0 comments

Nintendo Wii Themed Portfolio

https://akiraux.vercel.app/
1•s4074433•18m ago•1 comments

"There must be something like the opposite of suicide "

https://post.substack.com/p/there-must-be-something-like-the
1•rbanffy•20m ago•0 comments

Ask HN: Why doesn't Netflix add a “Theater Mode” that recreates the worst parts?

2•amichail•21m ago•0 comments

Show HN: Engineering Perception with Combinatorial Memetics

1•alan_sass•27m ago•2 comments

Show HN: Steam Daily – A Wordle-like daily puzzle game for Steam fans

https://steamdaily.xyz
1•itshellboy•29m ago•0 comments

The Anthropic Hive Mind

https://steve-yegge.medium.com/the-anthropic-hive-mind-d01f768f3d7b
1•spenvo•29m ago•0 comments

Just Started Using AmpCode

https://intelligenttools.co/blog/ampcode-multi-agent-production
1•BojanTomic•31m ago•0 comments

LLM as an Engineer vs. a Founder?

1•dm03514•32m ago•0 comments

Crosstalk inside cells helps pathogens evade drugs, study finds

https://phys.org/news/2026-01-crosstalk-cells-pathogens-evade-drugs.html
2•PaulHoule•33m ago•0 comments

Show HN: Design system generator (mood to CSS in <1 second)

https://huesly.app
1•egeuysall•33m ago•1 comments

Show HN: 26/02/26 – 5 songs in a day

https://playingwith.variousbits.net/saturday
1•dmje•34m ago•0 comments

Toroidal Logit Bias – Reduce LLM hallucinations 40% with no fine-tuning

https://github.com/Paraxiom/topological-coherence
1•slye514•36m ago•1 comments

Top AI models fail at >96% of tasks

https://www.zdnet.com/article/ai-failed-test-on-remote-freelance-jobs/
5•codexon•36m ago•2 comments

The Science of the Perfect Second (2023)

https://harpers.org/archive/2023/04/the-science-of-the-perfect-second/
1•NaOH•37m ago•0 comments

Bob Beck (OpenBSD) on why vi should stay vi (2006)

https://marc.info/?l=openbsd-misc&m=115820462402673&w=2
2•birdculture•41m ago•0 comments

Show HN: a glimpse into the future of eye tracking for multi-agent use

https://github.com/dchrty/glimpsh
1•dochrty•41m ago•0 comments