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Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy

https://www.nature.com/articles/s41586-025-09370-8
4•bookofjoe•7h ago

Contact the ISS

https://www.ariss.org/contact-the-iss.html
2•thunderbong•2m ago•0 comments

Bro, ban me at the IP level if you don't like me

https://boston.conman.org/2025/08/21.1
2•classichasclass•5m ago•0 comments

Time-Series Clustering: A Comprehensive Study of Data Mining, ML, and DL Methods [pdf]

https://www.vldb.org/pvldb/vol18/p4380-paparrizos.pdf
1•mfiguiere•8m ago•0 comments

Which Programming Language Should I Teach First: the least productive question

https://parentheticallyspeaking.org/articles/first-language-wrong-question/
2•matt_d•8m ago•0 comments

Git-Annex

https://git-annex.branchable.com/
1•keepamovin•10m ago•0 comments

Handling 500M clicks with a $4 VPS [video]

https://www.youtube.com/watch?v=nk3Ti0tCGvA
1•patatero•13m ago•0 comments

Physical AI: The next AI wave?

https://www.adlittle.com/en/insights/viewpoints/physical-ai
1•teleforce•13m ago•0 comments

Show HN: I made a WASI orchestration prototype

https://github.com/x3haloed/peer-deploy
1•x3haloed•16m ago•0 comments

Ersatz Good

https://en.wikipedia.org/wiki/Ersatz_good
3•sans_souse•17m ago•0 comments

WordPress Login Security with Fail2ban

https://joshtronic.com/2025/08/03/wordpress-login-security-fail2ban/
1•bubblebeard•19m ago•0 comments

We Might Be Alone

https://www.youtube.com/watch?v=zcInt58juL4
1•cgriswald•19m ago•0 comments

Double Bishops: The Silent Killers of Chess

https://lichess.org/@/Puli1234/blog/double-bishops-the-silent-killers-of-chess/On8mWrUJ
2•fzliu•21m ago•0 comments

Viewcounts of top Twitch streamers drop after platform cracks down on view bots

https://www.notebookcheck.net/Viewcounts-of-top-Twitch-streamers-plummet-after-platform-cracks-do...
3•MilnerRoute•23m ago•0 comments

Mario 64 wastes so much memory

https://www.youtube.com/watch?v=oZcbgNdWL7w
2•todsacerdoti•27m ago•0 comments

A Better Way to Think About AI

https://www.theatlantic.com/technology/archive/2025/08/ai-job-loss-human-enhancement-google/683963/
2•lantry•29m ago•0 comments

The last mid-1700s building in central Boston is for sale

https://happymuncher.com/historic-ebenezer-hancock-house-lists-in-boston-revolutionary-war-era-si...
2•Teever•30m ago•0 comments

How I avoid hitting Claude Code 5-hour limits early

https://harishgarg.com/how-i-avoid-hitting-claude-code-5-hour-limits-early
3•hgarg•30m ago•0 comments

Pure – static analysis file format checker for ZIP files

https://github.com/ronomon/pure
2•pabs3•38m ago•1 comments

Cash Experiment Cut Child Deaths in Half

https://www.vox.com/future-perfect/458767/givedirectly-infant-mortality-study
2•bdev12345•46m ago•0 comments

Ask HN: I just abandoned my PyCharm subscription, what should I use now?

3•jmward01•50m ago•0 comments

We need a new theory of democracy – because this version has failed

https://www.salon.com/2025/08/24/we-need-a-new-theory-of-democracy-because-this-version-has-failed/
8•hkhn•56m ago•0 comments

Free AI Security Testing

2•aiagentlover•57m ago•1 comments

The Revolution Will Not Be Star Wars: What Andor Depicts

https://www.nybooks.com/online/2025/07/24/the-revolution-will-not-be-star-wars/
3•mitchbob•59m ago•1 comments

Etomidate to Be Listed in Misuse of Drugs Act from Sep 1 in Singapore

https://www.channelnewsasia.com/singapore/vaping-etomidate-kpods-class-c-drug-ong-ye-kung-5311236
3•kelt•1h ago•0 comments

The fastest sorting algorithm [video]

https://www.youtube.com/watch?v=Y95a-8oNqps
2•hundredwatt•1h ago•0 comments

I can prove I've solved this sudoku without revealing it [video]

https://www.youtube.com/watch?v=Otvcbw6k4eo
4•hundredwatt•1h ago•0 comments

Why wind farms attract so much misinformation and conspiracy theory

https://theconversation.com/why-wind-farms-attract-so-much-misinformation-and-conspiracy-theory-2...
4•voxadam•1h ago•0 comments

Ask HN: Has anyone made an MCP server for calorie tracking?

3•joshcsimmons•1h ago•0 comments

Typeclassopedia

https://wiki.haskell.org/index.php?title=Typeclassopedia
2•marvinborner•1h ago•0 comments

Digital Cargo Cult: How Zoomers Ruined Old Internet Nostalgia

https://cy-x.net/articles?id=13
4•Kokouane•1h ago•0 comments