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Origins of life: the molecules that could have unlocked peptide synthesis

https://www.nature.com/articles/d41586-025-02518-6
3•jandrewrogers•2h ago

We Oops-Proofed Infrastructure Deletion on Railway

https://blog.railway.com/p/how-we-oops-proofed-infrastructure-deletion-on-railway
1•thisismahmoud_•28s ago•0 comments

From the 'Banter Bill' to Bias Hotlines: The Alarming Rise of Snitch Networks

https://thedailyeconomy.org/article/the-dangerous-rise-of-snitch-networks/
1•dmitrygr•2m ago•0 comments

The latest Covid vaccines come with restrictions

https://www.npr.org/sections/shots-health-news/2025/08/27/nx-s1-5515503/fda-covid-vaccines-restri...
1•metabagel•2m ago•1 comments

The big idea: Turn lobbying into a high-stakes financial market

https://nodumbideas.com/p/the-big-idea-decentralized-lobbying
1•hhs•2m ago•0 comments

Mainframe upgrade done with wire cutters (2015)

https://alt.folklore.computers.narkive.com/nZagiUHj/mainframe-upgrade-done-with-wire-cutters
1•WorldPeas•3m ago•0 comments

Python: The Documentary

https://lwn.net/Articles/1035537/
1•chmaynard•6m ago•0 comments

Show HN: DeepShot – an open-source NBA predictor with ML, EWMA, and live UI

https://github.com/saccofrancesco/deepshot
1•f_sacco•8m ago•0 comments

ExxonMobil Global Outlook: Our view to 2050

https://corporate.exxonmobil.com/sustainability-and-reports/global-outlook
1•mxschumacher•9m ago•1 comments

oLLM – LLM Inference for large-context tasks on consumer GPUs

https://github.com/Mega4alik/ollm
2•anuarsh•14m ago•0 comments

Should We Anthropomorphize LLMs?

https://aethermug.com/posts/there-is-thinking-and-there-is-thinking-and-there-is-thinking
1•mrcgnc•22m ago•0 comments

Prompt Engineering for Grok Code Fast 1

https://docs.x.ai/docs/guides/grok-code-prompt-engineering
1•empressplay•22m ago•0 comments

All Revenue Is Not Created Equal (2011)

https://abovethecrowd.com/2011/05/24/all-revenue-is-not-created-equal-the-keys-to-the-10x-revenue...
1•lispybanana•23m ago•0 comments

Ask HN: How much better can the LLMs become assuming no AGI

1•yalogin•23m ago•0 comments

The A.I. Talent Wars

https://www.nytimes.com/2025/08/25/podcasts/the-daily/ai-salaries-tech-silicon-valley.html
1•doener•24m ago•0 comments

Garmin Blaze Equine Wellness System

https://www.garmin.com/en-US/p/1277934/
1•carabiner•26m ago•0 comments

RSS Is Awesome

https://evanverma.com/rss-is-awesome
15•edverma2•30m ago•0 comments

Why HyperCard Had to Die (2011)

https://www.loper-os.org/?p=568
4•mgrayson•31m ago•2 comments

Hygiene Hypothesis

https://en.wikipedia.org/wiki/Hygiene_hypothesis
2•Jimmc414•35m ago•0 comments

The ABC Programming Language

https://homepages.cwi.nl/~steven/abc/
2•TheFreim•36m ago•0 comments

The Electro-Industrial Stack Will Move the World

https://a16z.com/the-electro-industrial-stack-will-move-the-world/
2•lemonberry•41m ago•0 comments

US withdraws from UN human rights report

https://www.reuters.com/world/europe/us-withdraws-key-un-human-rights-report-draws-criticism-righ...
5•geox•41m ago•0 comments

I've always wanted to be an open-source maintainer- now I regret it

https://joaomagfreitas.link/for-years-ive-always-wanted-to-be-an-open-source-maintainer/
3•freitzzz•43m ago•0 comments

Show HN: NamesMixer – brandable, available domain ideas in seconds

2•Names_Mixer•44m ago•1 comments

Show HN: A new interface for doing research fast with an LLM

https://www.proread.ai/
2•kanodiaashu•45m ago•0 comments

Why Intel investors have embraced an interventionist White House

https://www.ft.com/content/255a841a-0bf6-4e02-8735-bf8944f2522e
2•alephnerd•46m ago•0 comments

Expressions Are Coming to Pandas

https://labs.quansight.org/blog/pandas_expressions
3•TheAlchemist•1h ago•0 comments

OTC products evaluated for depressive symptoms

https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1609605/full
2•wjb3•1h ago•0 comments

Effective cerebellar neuroprosthetic control after stroke

https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00801-0?_returnURL=https%3A%2F%2Flinking...
2•PaulHoule•1h ago•0 comments

Porton's Lumo AI Chat releases v1.1

https://proton.me/blog/lumo-1-1
3•moelf•1h ago•0 comments

Every Industry Is an Overcrowded Airport Lounge Now

https://quoththeraven.substack.com/p/every-industry-is-an-overcrowded
3•walterbell•1h ago•0 comments