The craziest part about this is that it's true, when Tylenol was approved it was studied for acute toxicity, but at the time we didn't know how to study for long term neurological toxicity.
bigyabai•5mo ago
Do we have the data that confirms this? It may well be true, but still not the leading cause of autism.
rogerkirkness•5mo ago
Definitely not the leading cause of autism, definitely a contributing factor to the complicated generic expression cascade that can lead to autism [1].
"We identified 46 studies for inclusion in our analysis. Of these, 27 studies reported positive associations (significant links to NDDs), 9 showed null associations (no significant link), and 4 indicated negative associations (protective effects). Higher-quality studies were more likely to show positive associations. Overall, the majority of the studies reported positive associations of prenatal acetaminophen use with ADHD, ASD, or NDDs in offspring, with risk-of-bias and strength-of-evidence ratings informing the overall synthesis."
Why don't you type 'paracetamol autism' into Google Scholar, too hard for you?
"We identified 46 studies for inclusion in our analysis. Of these, 27 studies reported positive associations (significant links to NDDs), 9 showed null associations (no significant link), and 4 indicated negative associations (protective effects). Higher-quality studies were more likely to show positive associations. Overall, the majority of the studies reported positive associations of prenatal acetaminophen use with ADHD, ASD, or NDDs in offspring, with risk-of-bias and strength-of-evidence ratings informing the overall synthesis."
> Why don't you type 'paracetamol autism' into Google Scholar, too hard for you?
Please avoid swipes like this on HN.
jleyank•5mo ago
Google is often like drinking from a firehouse and my skill set doesn’t include bio- or medicinal chemistry. Hard to evaluate the output w/o the proper skills.
rogerkirkness•5mo ago
bigyabai•5mo ago
rogerkirkness•5mo ago
"We identified 46 studies for inclusion in our analysis. Of these, 27 studies reported positive associations (significant links to NDDs), 9 showed null associations (no significant link), and 4 indicated negative associations (protective effects). Higher-quality studies were more likely to show positive associations. Overall, the majority of the studies reported positive associations of prenatal acetaminophen use with ADHD, ASD, or NDDs in offspring, with risk-of-bias and strength-of-evidence ratings informing the overall synthesis."
Added link for lazy people who don't have Google.
[1] https://ehjournal.biomedcentral.com/articles/10.1186/s12940-...
jleyank•5mo ago
rogerkirkness•5mo ago
"We identified 46 studies for inclusion in our analysis. Of these, 27 studies reported positive associations (significant links to NDDs), 9 showed null associations (no significant link), and 4 indicated negative associations (protective effects). Higher-quality studies were more likely to show positive associations. Overall, the majority of the studies reported positive associations of prenatal acetaminophen use with ADHD, ASD, or NDDs in offspring, with risk-of-bias and strength-of-evidence ratings informing the overall synthesis."
[1]: https://ehjournal.biomedcentral.com/articles/10.1186/s12940-...
tomhow•5mo ago
Please avoid swipes like this on HN.
jleyank•5mo ago