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Mosquito Saliva Proteins as Blueprints for Vaccines and Non-Opioid Drugs

https://www.preprints.org/manuscript/202509.0782/v1
2•WASDAai•5h ago

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WASDAai•5h ago
TL;DR: A new preprint explores the mosquito sialome (saliva proteome), showing how its proteins act as anticoagulants, immune modulators, and even pain suppressors. Beyond vector biology, these molecules could inspire vaccines against mosquito-borne diseases and novel therapeutics (anti-inflammatory, antiviral, non-opioid analgesics, anticoagulants). Early-stage research, but intriguing biotech potential.

Are Best Practices Best?

https://quarter--mile.com/Are-Best-Practices-Best
1•surprisetalk•18s ago•0 comments

Show HN: Context, Hallucinations, and How LLMs Are Changing Development

https://juanpabloaj.substack.com/p/context-hallucinations-and-how-llms
1•juanpabloaj•25s ago•0 comments

The MCP Registry

http://blog.modelcontextprotocol.io/posts/2025-09-08-mcp-registry-preview/
1•jasonmorganson•1m ago•0 comments

Running 10 coding agents in isolation

https://www.youtube.com/watch?v=cTCTsTXWo6s
1•gk1•1m ago•0 comments

Disrupting the DRAM roadmap with capacitor-less IGZO-DRAM technology

https://www.imec-int.com/en/articles/disrupting-dram-roadmap-capacitor-less-igzo-dram-technology
1•ksec•1m ago•0 comments

Active-Descendant Console Debugger

https://html5accessibility.com/stuff/2025/09/03/active-descendant-console-debugger/
1•speckx•1m ago•0 comments

Tiny Tubes Reveal Clues to the Evolution of Complex Life

https://www.quantamagazine.org/tiny-tubes-reveal-clues-to-the-evolution-of-complex-life-20250908/
1•pseudolus•3m ago•0 comments

Tesla gives up on Cybertruck wireless charging

https://electrek.co/2025/09/09/tesla-gives-up-on-cybertruck-wireless-charging/
1•DamnInteresting•3m ago•0 comments

Claude can now create and edit files

https://www.anthropic.com/news/create-files
3•meetpateltech•3m ago•0 comments

Simon Wardley – From here to there and back again

https://www.youtube.com/watch?v=hEjjCI3kTM4
1•RebootStr•4m ago•0 comments

New Mexico is first state in US to offer universal child care

https://www.governor.state.nm.us/2025/09/08/new-mexico-is-first-state-in-nation-to-offer-universa...
1•toomuchtodo•4m ago•0 comments

Ask HN: What is your experience with Go's Green Tea GC?

1•gethly•5m ago•0 comments

The risks of cognitive offloading [to AI]

https://siliconangle.com/2025/09/05/hidden-risks-cognitive-offloading/
1•ptrhvns•6m ago•0 comments

The Science of Making Fruits and Veggies Last Longer [video]

https://www.youtube.com/watch?v=mhLWUjB2ox4
1•stevenjgarner•7m ago•0 comments

Digital resiliency 2025, my first self-audit

https://andrew-quinn.me/digital-resiliency-2025/
1•hiAndrewQuinn•7m ago•0 comments

China's social platforms rush to abide by AI-generated content labelling law

https://www.scmp.com/tech/policy/article/3323959/chinas-social-media-platforms-rush-abide-ai-gene...
2•ilamont•7m ago•0 comments

Remote, Hybrid, Office? Yes

https://virtualize.sh/blog/remote-hybrid-office-yes/
1•plam503711•8m ago•0 comments

Two Words Broke My LLM Chat Agent

https://schneidenba.ch/how-two-words-broke-my-llm-powered-chat-agent/
1•schneidenbach•10m ago•0 comments

The Boring Future of GenAI

https://blog.circuitsofimagination.com/2025/09/05/the-boring-future-of-genai.html
1•Bogdanp•10m ago•0 comments

Pre-owned software trial kicks off in UK as Microsoft pushes resale ban

https://www.theregister.com/2025/09/08/microsoft_valuelicensing_latest/
1•Lio•12m ago•0 comments

Wikifreedia

https://wikifreedia.xyz/
1•altilunium•14m ago•0 comments

The Beast Behind ChatGPT

https://powellg.substack.com/p/chatgpt-orchestration
1•scrumbuddy_ai•14m ago•0 comments

Obs.js – context-aware web performance for everyone

https://csswizardry.com/Obs.js/demo/
1•speckx•14m ago•0 comments

Show HN: BPM Finder: Advanced Audio Analysis Toolkit

https://bpm-finder.net
1•yxchen1994•17m ago•0 comments

Major Attack on Node.js

https://www.heise.de/en/news/Major-attack-on-node-js-10637093.html
1•MarcusE1W•17m ago•2 comments

Switching Back to Bash from Zsh

https://www.codyhiar.com/blog/switching-back-to-bash-from-zsh/
3•srid•17m ago•0 comments

Show HN: Narev – Rapid A/B tests for the LLM setup

https://www.narev.ai/
1•osquar•19m ago•0 comments

Mark Hoppus of Blink-182 Probably Helped Catch Saddam Hussein [video]

https://www.youtube.com/watch?v=3SlqIxX_wZA
1•keepamovin•19m ago•0 comments

Fastest website in Japan – Hiroshi Abe's homepage

http://abehiroshi.la.coocan.jp/
2•sdovan1•20m ago•0 comments

Show HN: Paylooop – Cost visibility for AI agents

9•yahyam•20m ago•0 comments