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Interop 2025: A Year of Convergence

https://webkit.org/blog/17808/interop-2025-review/
1•ksec•9m ago•0 comments

JobArena – Human Intuition vs. Artificial Intelligence

https://www.jobarena.ai/
1•84634E1A607A•13m ago•0 comments

Concept Artists Say Generative AI References Only Make Their Jobs Harder

https://thisweekinvideogames.com/feature/concept-artists-in-games-say-generative-ai-references-on...
1•KittenInABox•17m ago•0 comments

Show HN: PaySentry – Open-source control plane for AI agent payments

https://github.com/mkmkkkkk/paysentry
1•mkyang•19m ago•0 comments

Show HN: Moli P2P – An ephemeral, serverless image gallery (Rust and WebRTC)

https://moli-green.is/
1•ShinyaKoyano•28m ago•0 comments

The Crumbling Workflow Moat: Aggregation Theory's Final Chapter

https://twitter.com/nicbstme/status/2019149771706102022
1•SubiculumCode•32m ago•0 comments

Pax Historia – User and AI powered gaming platform

https://www.ycombinator.com/launches/PMu-pax-historia-user-ai-powered-gaming-platform
2•Osiris30•33m ago•0 comments

Show HN: I built a RAG engine to search Singaporean laws

https://github.com/adityaprasad-sudo/Explore-Singapore
1•ambitious_potat•39m ago•0 comments

Scams, Fraud, and Fake Apps: How to Protect Your Money in a Mobile-First Economy

https://blog.afrowallet.co/en_GB/tiers-app/scams-fraud-and-fake-apps-in-africa
1•jonatask•39m ago•0 comments

Porting Doom to My WebAssembly VM

https://irreducible.io/blog/porting-doom-to-wasm/
1•irreducible•40m ago•0 comments

Cognitive Style and Visual Attention in Multimodal Museum Exhibitions

https://www.mdpi.com/2075-5309/15/16/2968
1•rbanffy•41m ago•0 comments

Full-Blown Cross-Assembler in a Bash Script

https://hackaday.com/2026/02/06/full-blown-cross-assembler-in-a-bash-script/
1•grajmanu•46m ago•0 comments

Logic Puzzles: Why the Liar Is the Helpful One

https://blog.szczepan.org/blog/knights-and-knaves/
1•wasabi991011•58m ago•0 comments

Optical Combs Help Radio Telescopes Work Together

https://hackaday.com/2026/02/03/optical-combs-help-radio-telescopes-work-together/
2•toomuchtodo•1h ago•1 comments

Show HN: Myanon – fast, deterministic MySQL dump anonymizer

https://github.com/ppomes/myanon
1•pierrepomes•1h ago•0 comments

The Tao of Programming

http://www.canonical.org/~kragen/tao-of-programming.html
2•alexjplant•1h ago•0 comments

Forcing Rust: How Big Tech Lobbied the Government into a Language Mandate

https://medium.com/@ognian.milanov/forcing-rust-how-big-tech-lobbied-the-government-into-a-langua...
3•akagusu•1h ago•0 comments

PanelBench: We evaluated Cursor's Visual Editor on 89 test cases. 43 fail

https://www.tryinspector.com/blog/code-first-design-tools
2•quentinrl•1h ago•2 comments

Can You Draw Every Flag in PowerPoint? (Part 2) [video]

https://www.youtube.com/watch?v=BztF7MODsKI
1•fgclue•1h ago•0 comments

Show HN: MCP-baepsae – MCP server for iOS Simulator automation

https://github.com/oozoofrog/mcp-baepsae
1•oozoofrog•1h ago•0 comments

Make Trust Irrelevant: A Gamer's Take on Agentic AI Safety

https://github.com/Deso-PK/make-trust-irrelevant
7•DesoPK•1h ago•4 comments

Show HN: Sem – Semantic diffs and patches for Git

https://ataraxy-labs.github.io/sem/
1•rs545837•1h ago•1 comments

Hello world does not compile

https://github.com/anthropics/claudes-c-compiler/issues/1
35•mfiguiere•1h ago•20 comments

Show HN: ZigZag – A Bubble Tea-Inspired TUI Framework for Zig

https://github.com/meszmate/zigzag
3•meszmate•1h ago•0 comments

Metaphor+Metonymy: "To love that well which thou must leave ere long"(Sonnet73)

https://www.huckgutman.com/blog-1/shakespeare-sonnet-73
1•gsf_emergency_6•1h ago•0 comments

Show HN: Django N+1 Queries Checker

https://github.com/richardhapb/django-check
1•richardhapb•1h ago•1 comments

Emacs-tramp-RPC: High-performance TRAMP back end using JSON-RPC instead of shell

https://github.com/ArthurHeymans/emacs-tramp-rpc
1•todsacerdoti•1h ago•0 comments

Protocol Validation with Affine MPST in Rust

https://hibanaworks.dev
1•o8vm•2h ago•1 comments

Female Asian Elephant Calf Born at the Smithsonian National Zoo

https://www.si.edu/newsdesk/releases/female-asian-elephant-calf-born-smithsonians-national-zoo-an...
5•gmays•2h ago•1 comments

Show HN: Zest – A hands-on simulator for Staff+ system design scenarios

https://staff-engineering-simulator-880284904082.us-west1.run.app/
1•chanip0114•2h ago•1 comments
Open in hackernews

Daily Aspirin intake slashes colon cancer relapse risk by 55%

https://news.ki.se/common-inexpensive-drug-halves-recurrence-in-colorectal-cancer
25•eyk19•4mo ago

Comments

leakycap•4mo ago
... "with a certain type of genetic alteration in the tumor."

This genetic alteration is found in slightly more than 1/3 of patients.

I guess "Anti-inflammatory medication for 3 years after colorectal surgery reduces relapse risk for 55% of 38% of patients" doesn't have the same hopeful ring to it, but I'd prefer honesty.

coldtea•4mo ago
For that 38% subset it reduces the risk at 55%, so there's that

(plus 38% is not 0.1%)

leakycap•4mo ago
No comment other than yours references 38% being at all similar to 0.1%

"So there's that" is not usually slapped on the end of compelling arguments.

Any other reasons to support this style of clickbaity title instead of something intellectually honest that doesn't deflate hope as the reader goes beyond the headline?

coldtea•4mo ago
>No comment other than yours references 38% being at all similar to 0.1%

Pedantic much? Ever stopped to wonder if there was a point being made, and not a verbatim reference to what a comment said?

The point being 38% is substantial enough for it's 55% to matter. It's not like it just applies to some tiny slice of patients (the proverbial 0.1% - and please don't tell me there's no proverb mentioning 0.1% either).

>Any other reasons to support this style of clickbaity title instead of something intellectually honest that doesn't deflate hope as the reader goes beyond the headline

It does rellapse the risk by 55% (or at least, it would, if the finding replicates and is accurate). It's just that it's the risk for a specific case.

People shouldn't look for hope from headlines to begin with, nor put too much faith on this or that individual announcement. Nor follow something without consulting with a doctor or two.

In this case it's easier for an individual to just try themselves, since it only involves aspirin intake, but in the general case, most such announcements don't go nowhere near of resulting to some new drug, or to being pratictaly applied as part of regular protocols.

leakycap•4mo ago
> Penantic much?

Pedantic would be pointing out your spelling error. Now you can call me that again but you'll be correct this time.

> In this case it's easier for an individual to just try themselves, since it only involves aspirin intake

The fact this is your takeaway, even after I used numeric values to explain the overpromise of the headline... wow. Your wild takeaway is exactly why clickbaity, overpromising headlines do real damage.

coldtea•4mo ago
Nope, pedantic is also focusing on taking something literally, when it's an obvious device to make a point.

>The fact this is your takeaway, even after I used numeric values to explain the overpromise of the headline... wow

I covered the overpromise and even explained why it's still a big enough development. This part was making another point that also went wooooosh (about how such findings rarely materialize to treatment, and people shouldn't get their hopes high from headlines to begin with, even IF the finding they write about covers all or most of the cases and not just 55% of 38% of them - and that this is a general rule, even if in this case one can just trivially try the treatment themselves without waiting for a new drug).

I mean, one has to spell it out, and it still IS pedantically misread.

leakycap•4mo ago
> why it's still a big enough development.

It seems we agree: the hyperbolic, misleading headline wasn't necessary.

I appreciate our interaction as a reminder that even numbers do not clearly communicate information to everyone. This will help me to remember I should exercise caution in what I write to make the point abundantly clear.

I would never want to put end users in situations where they might harm themselves by taking a pill daily based on a poorly worded headline on a tech website. Good luck to you and your new aspirin regimen, though!

coldtea•4mo ago
>I would never want to put end users in situations where they might harm themselves by taking a pill daily based on a poorly worded headline on a tech website. Good luck to you and your new aspirin regimen, though!

People who would do that because of some single paper (most don't replicate anyway), without checking with a doctor, and taking into account general consensus on the matter, are going to do shit like that anyway, this individual headline wont make any difference.

leakycap•4mo ago
> this individual headline wont make any difference

Ah, yes, the excuse that individual actions don't matter in the larger scheme of the world. Dismissing things is convenient when you don't want to think about them anymore.

add-sub-mul-div•4mo ago
You quoted the first sentence of the article. The headline is not supposed to contain all information from the article. We are not better off with a norm that we refuse to read past the headline and therefore consider the first paragraph of the actual article to be hidden.
leakycap•4mo ago
I read the article, hence why I immediately noticed the disconnect. Mary Had a Little Lamb doesn't tell the whole story, but it doesn't say Mary's Magic Lamb Does Her Homework, either.

I guess intellectual dishonesty in links is so common some people don't even care anymore.

mannyv•4mo ago
For two specific groups, aspirin reduces the recurrence of colorectal cancer by around 50%.

Group a: 7.7% with aspirin vs 14.1% recurrence without aspirin.

Group b: 7.7% with aspirin vs 16.8% recurrence without aspirin.

What's nice is that these are real occurrences, not relative risk percentages. They don't need fuzzy numbers to make their results significant.

Of course, there's also the line at the bottom: "Severe adverse events occurred in 16.8% of aspirin recipients and 11.6% of placebo recipients." Ouch. So if you can make it past that increase in severe adverse events you'll be fine.

sudoshred•4mo ago
How severe? Worse than colon cancer?
nikolay•4mo ago
People don't know how to take aspirin! There are side effects other than stomach bleeding, but this most frequent issue is easily countered by taking pure aspirin together with DGL or vitamin C... or maybe both. I've heard it from a person who's in aspirin research taking it with gelatin also addresses the potential bleeding.