Extraordinary claims require extraordinary evidence. What evidence do you have that we are 100 years from going post-human or post biological? Technology is fascinating but all of the technology that we have ever created has not even come close to the complexity of the most simple biology. All existing evidence is that biological life is far more complex, and adaptable, than any technological creation that can be made. While scientists understand these biological compounds It has alluded them on how to organize them into even the most simple microbe that we know about.

The far more likely thing is that in the next hundred years we will see our crude technology come to mimic biology.

So you're talking about an unsolved problem that has no evidence pointing to any solution. You're claiming there are different ways to organize life but where is the evidence there is different ways to organize life than what we have seen? That's how you formulate a hypothesis and then you begin to test it. Without that you're simply speaking fantasy. There are definitely unknowns but all the evidence points to life would be like us in the generic sense that it is biological and based upon similar biological compounds. It's form may take different shapes It's perception maybe things that we don't understand yet but there is zero evidence of life being capable organizing itself around a completely foreign system than what we've seen.

I welcome research in that direction to show that life can be organized around fundamentally different things than what we've seen but fantastical ideas from science fantasy stories do not help actual research happen.