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Even light alcohol drinking raises dementia risk, according to largest study

https://www.psypost.org/even-light-alcohol-drinking-raises-dementia-risk-according-to-largest-genetic-study-to-date/
11•ivewonyoung•1h ago

Comments

physarum_salad•53m ago
Surely there is a fermented or psychoactive drink that we can switch too with equal sociability/giggles. Very low concentrations of psychedelics served in a bar setting?
DaveZale•51m ago
kava?
nerdsniper•39m ago
GHB is “technically” safer than alcohol at target doses, but dosing range is narrower than alcohol and negative effects of overconsumption are more severe. So safer in theory, but generally more dangerous in practice.

There’s something to be advocated for recreational drug users to replace the usual “maximum effect dose” of drugs they do occasionally (MDMA, cocaine, etc) with the equivalent of “two beers worth” of their drug of choice. But generally recreational drugs destabilize brain chemistry for 2-8 weeks regardless of dose - less is better of course, but people also shouldn’t think its okay to use it more frequently just because they’re doing a smaller dose - the side effects will be less but recovery will generally still take about as long.

I often tell my friends that less is more. Some have started to come to understand that to be true for them.

chistev•33m ago
What are the benefits of alcohol again?
nerdsniper•32m ago
Can facilitate deeper interpersonal connection and sometimes intrapersonal insight.

There do seem to be a lot of downsides though.

quickthrowman•28m ago
In my opinion, aside from in vino, veritas, there aren’t any.

The most common answer you’ll get is ‘social lubricant’, which I’ll admit is somewhat true in groups of strangers or acquaintances.

However, most people can use alcohol responsibly and enjoy themselves without harming others (or themselves). Most of the things we do or put in our bodies have risks associated.

Legend2440•8m ago
It’s fun!

How to choose the correct fishing lure?

https://fisherlures.com/blogs/fishing-lures/how-to-choose-your-lure
1•erayalakese•4m ago•0 comments

Pope Leo refuses to authorise an AI Pope

https://www.pcgamer.com/software/ai/pope-leo-refuses-to-authorise-an-ai-pope-and-declares-the-tec...
2•pseudolus•9m ago•0 comments

Be Wary of Compromise

https://thealephengine.substack.com/p/be-wary-of-compromise
1•enjeyw•13m ago•2 comments

Mapping Radioactive Fallout in the United States

https://makingmaps.net/2011/03/18/mapping-radioactive-fallout-in-the-united-states/
3•georgecmu•15m ago•0 comments

Which country is the most influential partner in Southeast Asia?

https://influence.lowyinstitute.org/
2•sings•16m ago•0 comments

Novel phishing attack via GitHub notifications

https://dunkirk.sh/blog/github-phishing/
1•clacker-o-matic•17m ago•0 comments

The Lamborghini of APC's: IDF's Eitan

https://www.ynetnews.com/magazine/article/rkqtpjznle
1•datelligence•18m ago•0 comments

Practical Panpsychism

https://podcast.everydaysystems.com/episode/98/
1•surprisetalk•19m ago•0 comments

How did sports betting become legal in the US?

https://shreyashariharan.substack.com/p/how-did-sports-betting-become-legal
2•_1729•21m ago•0 comments

Docker Hub Is Down

https://www.dockerstatus.com/pages/incident/533c6539221ae15e3f000031/68d47a2f93c09e05486d93a9
8•cipherself•21m ago•0 comments

Sense and Sensitivity (2019)

https://hyperparameter.space/blog/sense-and-sensitivity-and-specificty-and-utility/
1•detreatsie•23m ago•0 comments

Pay for your children's art, Australian kindergarten tells stunned parents

https://www.bbc.com/news/articles/cq8ed2g95zlo
1•tartoran•23m ago•0 comments

SEC forgives three scammers who bilked Americans out of millions

https://www.msn.com/en-us/money/companies/trump-s-sec-forgives-three-scammers-who-bilked-american...
1•petethomas•23m ago•0 comments

Do YC after you graduate: Early decision for students

https://www.ycombinator.com/early-decision
10•snowmaker•24m ago•4 comments

I built a CLI to test and eval MCP servers

https://www.npmjs.com/package/@mcpjam/cli
2•matt8p•24m ago•1 comments

Tylenol in pregnancy linked to higher autism risk, Harvard scientists report

https://www.sciencedaily.com/releases/2025/09/250924012222.htm
2•OutOfHere•27m ago•1 comments

Human Drivers Will Kill 11 People While You Read This

https://secondthoughts.ai/p/autonomous-vehicles-will-save-lives
3•gk1•27m ago•0 comments

DockerHub Is Down [Auth]

https://registry-1.docker.io/v2/library/golang/manifests/1.24.5-alpine
4•thehamkercat•33m ago•1 comments

Is cashless bail leading to spikes in jail population?

https://www.nbcchicago.com/news/local/chicago-politics/is-cashless-bail-leading-to-spikes-in-jail...
1•stockresearcher•33m ago•1 comments

Intel Seeks Investment from Apple

https://finance.yahoo.com/news/intel-seeks-investment-apple-bloomberg-200530381.html
3•mgh2•36m ago•0 comments

Docker Hub is down (again)

https://hub.docker.com/_/python
12•frabonacci•36m ago•2 comments

Indeed updated terms: Forced Arbitration and bundling of consent

https://consumerrights.wiki/w/Indeed_Forced_Arbitration_%26_bundling_of_consent
1•Improvement•38m ago•0 comments

Sop Is All You Need

https://runbook.run/
1•clement1107•40m ago•0 comments

Show HN: Free Visual JSON Schema Builder (Generate, Validate and Export)

https://jsonpost.com/free-html-form-generator
1•ubergeekady•41m ago•0 comments

Helium Browser

https://helium.computer/
42•spacebuffer•46m ago•20 comments

The Rise of the Operator

https://markmaunder.com/2025/the-rise-of-the-operator/
1•mmaunder•46m ago•0 comments

Why MAGA Evangelicals Can Cheer Love and Hate at the Same Time

https://www.nytimes.com/2025/09/23/opinion/erika-kirk-charlie-trump-miller.html
5•whack•47m ago•5 comments

Fox News' Jesse Watters suggests bombing UN after Trump's escalator

https://www.nydailynews.com/2025/09/24/jesse-watters-bomb-gas-un-trump-escalator-teleprompter/
7•duxup•48m ago•2 comments

Autism Has Always Existed. We Haven't Always Called It Autism

https://www.nytimes.com/2025/09/24/opinion/autism-rates-science-diagnosis-parent.html
6•bell-cot•49m ago•0 comments

Show HN: I made an Airtable powered Drag-and-Drop Website Builder

https://shareables.ai/
1•Ryanwalker64•51m ago•0 comments