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The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•1m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•4m ago•2 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
1•sara_builds•4m ago•0 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•6m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•9m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•10m ago•0 comments

Hello

1•otrebladih•11m ago•0 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•14m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•16m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•18m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•20m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•24m ago•0 comments

.72% Variance Lance

1•mav5431•25m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•26m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•26m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•27m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•29m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•29m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•29m ago•1 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•30m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•30m ago•0 comments

South Korean crypto firm accidentally sends $44B in bitcoins to users

https://www.reuters.com/world/asia-pacific/crypto-firm-accidentally-sends-44-billion-bitcoins-use...
2•layer8•31m ago•0 comments

Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
1•atomic128•33m ago•2 comments

Web.whatsapp.com appears to be having issues syncing and sending messages

http://web.whatsapp.com
1•sabujp•34m ago•2 comments

Google in Your Terminal

https://gogcli.sh/
1•johlo•35m ago•0 comments

Shannon: Claude Code for Pen Testing: #1 on Github today

https://github.com/KeygraphHQ/shannon
1•hendler•35m ago•0 comments

Anthropic: Latest Claude model finds more than 500 vulnerabilities

https://www.scworld.com/news/anthropic-latest-claude-model-finds-more-than-500-vulnerabilities
2•Bender•40m ago•0 comments

Brooklyn cemetery plans human composting option, stirring interest and debate

https://www.cbsnews.com/newyork/news/brooklyn-green-wood-cemetery-human-composting/
1•geox•40m ago•0 comments

Why the 'Strivers' Are Right

https://greyenlightenment.com/2026/02/03/the-strivers-were-right-all-along/
1•paulpauper•41m ago•0 comments

Brain Dumps as a Literary Form

https://davegriffith.substack.com/p/brain-dumps-as-a-literary-form
1•gmays•42m ago•0 comments
Open in hackernews

Sharp rise in memory and thinking problems among U.S. adults

https://medicalxpress.com/news/2025-09-sharp-memory-problems-adults.html
32•GeoAtreides•4mo ago

Comments

Ancalagon•4mo ago
My knee-jerk reaction was complications from Covid. It's knee-jerk though so its probably wrong and more related to stress like the article hints at.
pcdoodle•4mo ago
Perhaps fast track product that released on the population in the past 5 years?
pavel_lishin•4mo ago
It's not that, although COVID has something to do with it. Under lockdowns, most people were told not to go outside, so we stayed put. Meanwhile, the Zetans were finally free to take the skies, and improve their cloaking technology without billions of people seeing them zoom across the stars. Now it's good enough that they can hover a few feet above you, spreading their rays. That's the cause of the memory and thinking issues.
DaveZale•4mo ago
thanks for clarifying that!

"The Zetans are a race of aliens that have been involved in the affairs of Earth and its inhabitants both before and after the Great War. They have appeared multiple times in the Fallout series."

pcdoodle•4mo ago
Thanks reddit!
gdulli•4mo ago
These days it takes more work than ever to craft a dumb enough statement to be recognized as unambiguously dumber than what's being satirized. Your effort isn't unnoticed.
metalman•4mo ago
you will take notice that acusations of synicisim are no longer made, and acknowledgements are more (as you demonstrate) about trying to find and mark the place where everything changed
DaveZale•4mo ago
Well, Steve Bannon is making good on his promise to have maga flood the media with BS. We were warned. It's cognitive warfare in his perspective, he even clearly said as much. At least that's a partial explanation.
Legend2440•4mo ago
…as measured by an online survey where they asked people if they think they have memory problems.

I’m skeptical of the quality of this result. Self-diagnosis is a poor measure of mental decline.

bikenaga•4mo ago
Original article: https://www.neurology.org/doi/10.1212/WNL.0000000000214226

They note that data from 2020 was excluded due to covid disruptions. They address the limitations of self-reported data in the discussion section at the end - and actually, the fact that the rates vary significantly depending on age, race, and income suggest that there is something going on here. In other words, the "actual" rates of cognitive disability, if you could measure them in a more objective, non self-reported way, might be different from what they found. But even so, the dependency of the rates on age, race, and income might be real.

more_corn•4mo ago
That explains EVERYTHING