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Making Antibodies as Ubiquitous as Aspirin

https://www.worksinprogress.news/p/the-antibody-factory
1•ortegaygasset•44s ago•0 comments

OpenSUSE Leap 16 out with safeguards against potential Y2K38 disaster

https://www.neowin.net/news/opensuse-leap-16-out-with-the-new-agama-installer-safeguards-against-...
1•bundie•2m ago•0 comments

Colorado investigators to review author Hunter S. Thompson's death

https://www.cnn.com/2025/09/30/us/hunter-s-thompson-death-review-colorado
1•pseudolus•3m ago•0 comments

Show HN: Marble – Learn new tech through building throwaway projects with AI

https://www.withmarble.ai/
1•miguelacevedo•5m ago•0 comments

Apriel-1.5-15B-Thinker

https://huggingface.co/ServiceNow-AI/Apriel-1.5-15b-Thinker
1•tosh•6m ago•0 comments

OpenStack in the pink with Flamingo release that escapes ancient Python grip

https://www.theregister.com/2025/10/01/openstack_flamingo_release/
1•rntn•7m ago•0 comments

Roland TR-1000 Rhythm Creator [video]

https://www.youtube.com/watch?v=6oDy4V8cn0k
1•gregsadetsky•7m ago•0 comments

Show HN: I built a prompt library for AI video generation, including Sora2

https://videoprompt.app/prompts/sora2
1•hr98w•7m ago•0 comments

Does GDP growth minus AI capex equal zero?

https://www.ft.com/content/603be7d5-13ac-4047-9854-24db5f0f0802
1•cs702•7m ago•1 comments

Kubernetes features stage changes in a visual way

https://kaniuse.gerome.dev/
1•Bogdanp•11m ago•0 comments

Mathematical Models/Algorithms for Optimization of Lego Construction Problems [pdf]

https://backend.orbit.dtu.dk/ws/portalfiles/portal/236623063/PhD_Thesis_Torkil_Kollsker.pdf
1•felineflock•11m ago•0 comments

MIT technology can see microbes from 90 meters away

https://www.asimov.press/p/hyperspectral
4•mailyk•12m ago•0 comments

Fivetran in talks with dbt Labs over multibillion-dollar big-data merger

https://siliconangle.com/2025/09/28/report-fivetran-talks-dbt-labs-multibillion-dollar-big-data-m...
1•kdazzle•15m ago•1 comments

AMD's EPYC 9355P: Inside a 32 Core Zen 5 Server Chip

https://chipsandcheese.com/p/amds-epyc-9355p-inside-a-32-core
1•rbanffy•15m ago•0 comments

Deta's Surf app is an amalgamation of an AI browser and NotebookLM

https://techcrunch.com/2025/10/01/detas-surf-app-is-an-amalgamation-of-an-ai-browser-and-notebooklm/
2•brechtknecht•16m ago•1 comments

Decentralizing Quality

https://matthewstrom.com/writing/decentralizing-quality/
4•Brajeshwar•17m ago•0 comments

Buy a vintage military airplane for $25

https://www.popsci.com/technology/buy-vintage-airplane-wyoming/
3•Brajeshwar•18m ago•0 comments

Bulging Biceps Don't Win Modern Wars – Paul Krugman

https://paulkrugman.substack.com/p/bulging-biceps-dont-win-modern-wars
5•rbanffy•18m ago•1 comments

Choose Boring Technology (2015)

https://mcfunley.com/choose-boring-technology
2•Brajeshwar•18m ago•0 comments

More tip jars appear at Japanese restaurants

https://soranews24.com/2025/10/01/more-tip-jars-appear-at-japanese-restaurants-but-there-are-impo...
2•askl•18m ago•0 comments

Self-tuning energy device turns vibrations into power

https://techxplore.com/news/2025-09-tuning-energy-device-vibrations-power.html
1•PaulHoule•20m ago•0 comments

Show HN: Infera – A DuckDB extension for in-database inference, written in Rust

https://github.com/CogitatorTech/infera
1•habedi0•20m ago•0 comments

New AI tool can detect melanoma with 99% accuracy

https://news.northeastern.edu/2025/10/01/melanoma-detection-ai/
2•geox•20m ago•1 comments

Inside Our Bid to Rescue Weebly from Square

https://www.articulation.blog/p/inside-our-bid-to-rescue-weebly-from-square
2•dustywusty•22m ago•0 comments

Detecting AI Fakes with Compression Artifacts

https://dmanco.dev/2025/09/15/basics-of-image-forensics-1.html
1•Fourthline•23m ago•0 comments

Show HN: OneTabMan

https://github.com/MathieuBordere/onetabman
1•letmetweakit•24m ago•0 comments

Sora 2: AI Video and Audio Generator – Create Realistic AI Videos

https://sora2-ai.io
1•sinpor1•27m ago•0 comments

Ask HN: Who is hiring? (October 2025)

8•whoishiring•27m ago•15 comments

Ask HN: Freelancer? Seeking freelancer? (October 2025)

3•whoishiring•27m ago•10 comments

Ask HN: Who wants to be hired? (October 2025)

5•whoishiring•27m ago•17 comments
Open in hackernews

Unix philosophy and filesystem access makes Claude Code amazing

https://www.alephic.com/writing/the-magic-of-claude-code
17•noahbrier•1h ago

Comments

xorvoid•47m ago
Let's do this. But entirely local. Local obsidian, local LLM, and all open source. That's the future I want.
smm11•26m ago
Apple then.
p_ing•15m ago
That rules out the open source part.
eadmund•23m ago
Local Org mode, local LLM, all orchestrated with Emacs, all free software.

If only I were retired and had infinite time!

gchamonlive•15m ago
Open-weights only are also not enough, we need control of the dataset and training pipeline.

The average user like me wouldn't be able to run pipelines without serious infrastructure, but it's very important to understand how the data is used and how the models are trained, so that we own the model and can assess its biases openly.

tsimionescu•2m ago
Good luck understanding the biases in a petabyte of text and images and video, or whatever the training set is.
xnx•17m ago
No mention/comparison to Gemini CLI? Gemini CLI is awesome and they just added a kind of stealth feature for Chrome automation. This capability was first announced as Project Mariner, and teased for eventual rollout in Chrome, but it's available right now for free in Gemini CLI.
nharada•14m ago
I do really like the Unix approach Claude Code takes, because it makes it really easy to create other Unix-like tools and have Claude use them with basically no integration overhead. Just give it the man page for your tool and it'll use it adeptly with no MCP or custom tool definition nonsense. I built a tool that lets Claude use the browser and Claude never has an issue using it.