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Postgres Message Queue (PGMQ)

https://github.com/pgmq/pgmq
1•Lwrless•3m ago•0 comments

Show HN: Django-rclone: Database and media backups for Django, powered by rclone

https://github.com/kjnez/django-rclone
1•cui•6m ago•1 comments

NY lawmakers proposed statewide data center moratorium

https://www.niagara-gazette.com/news/local_news/ny-lawmakers-proposed-statewide-data-center-morat...
1•geox•8m ago•0 comments

OpenClaw AI chatbots are running amok – these scientists are listening in

https://www.nature.com/articles/d41586-026-00370-w
2•EA-3167•8m ago•0 comments

Show HN: AI agent forgets user preferences every session. This fixes it

https://www.pref0.com/
4•fliellerjulian•10m ago•0 comments

Introduce the Vouch/Denouncement Contribution Model

https://github.com/ghostty-org/ghostty/pull/10559
2•DustinEchoes•12m ago•0 comments

Show HN: SSHcode – Always-On Claude Code/OpenCode over Tailscale and Hetzner

https://github.com/sultanvaliyev/sshcode
1•sultanvaliyev•12m ago•0 comments

Microsoft appointed a quality czar. He has no direct reports and no budget

https://jpcaparas.medium.com/microsoft-appointed-a-quality-czar-he-has-no-direct-reports-and-no-b...
1•RickJWagner•14m ago•0 comments

Multi-agent coordination on Claude Code: 8 production pain points and patterns

https://gist.github.com/sigalovskinick/6cc1cef061f76b7edd198e0ebc863397
1•nikolasi•14m ago•0 comments

Washington Post CEO Will Lewis Steps Down After Stormy Tenure

https://www.nytimes.com/2026/02/07/technology/washington-post-will-lewis.html
4•jbegley•15m ago•0 comments

DevXT – Building the Future with AI That Acts

https://devxt.com
2•superpecmuscles•16m ago•4 comments

A Minimal OpenClaw Built with the OpenCode SDK

https://github.com/CefBoud/MonClaw
1•cefboud•16m ago•0 comments

The silent death of Good Code

https://amit.prasad.me/blog/rip-good-code
3•amitprasad•16m ago•0 comments

The Internal Negotiation You Have When Your Heart Rate Gets Uncomfortable

https://www.vo2maxpro.com/blog/internal-negotiation-heart-rate
1•GoodluckH•18m ago•0 comments

Show HN: Glance – Fast CSV inspection for the terminal (SIMD-accelerated)

https://github.com/AveryClapp/glance
2•AveryClapp•19m ago•0 comments

Busy for the Next Fifty to Sixty Bud

https://pestlemortar.substack.com/p/busy-for-the-next-fifty-to-sixty-had-all-my-money-in-bitcoin-...
1•mithradiumn•20m ago•0 comments

Imperative

https://pestlemortar.substack.com/p/imperative
1•mithradiumn•21m ago•0 comments

Show HN: I decomposed 87 tasks to find where AI agents structurally collapse

https://github.com/XxCotHGxX/Instruction_Entropy
1•XxCotHGxX•24m ago•1 comments

I went back to Linux and it was a mistake

https://www.theverge.com/report/875077/linux-was-a-mistake
3•timpera•26m ago•1 comments

Octrafic – open-source AI-assisted API testing from the CLI

https://github.com/Octrafic/octrafic-cli
1•mbadyl•27m ago•1 comments

US Accuses China of Secret Nuclear Testing

https://www.reuters.com/world/china/trump-has-been-clear-wanting-new-nuclear-arms-control-treaty-...
3•jandrewrogers•28m ago•1 comments

Peacock. A New Programming Language

2•hashhooshy•32m ago•1 comments

A postcard arrived: 'If you're reading this I'm dead, and I really liked you'

https://www.washingtonpost.com/lifestyle/2026/02/07/postcard-death-teacher-glickman/
3•bookofjoe•34m ago•1 comments

What to know about the software selloff

https://www.morningstar.com/markets/what-know-about-software-stock-selloff
2•RickJWagner•37m ago•0 comments

Show HN: Syntux – generative UI for websites, not agents

https://www.getsyntux.com/
3•Goose78•38m ago•0 comments

Microsoft appointed a quality czar. He has no direct reports and no budget

https://jpcaparas.medium.com/ab75cef97954
2•birdculture•38m ago•0 comments

AI overlay that reads anything on your screen (invisible to screen capture)

https://lowlighter.app/
1•andylytic•40m ago•1 comments

Show HN: Seafloor, be up and running with OpenClaw in 20 seconds

https://seafloor.bot/
1•k0mplex•40m ago•0 comments

Tesla turbine-inspired structure generates electricity using compressed air

https://techxplore.com/news/2026-01-tesla-turbine-generates-electricity-compressed.html
2•PaulHoule•41m ago•0 comments

State Department deleting 17 years of tweets (2009-2025); preservation needed

https://www.npr.org/2026/02/07/nx-s1-5704785/state-department-trump-posts-x
5•sleazylice•41m ago•2 comments
Open in hackernews

High-fat diet impairs memory by autophagic-lysosomal dysfunction in Drosophila

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011818
25•PaulHoule•4mo ago

Comments

DaveZale•4mo ago
yes. Search pubmed.gov for some excellent reviews on high saturated fat diets and the blood brain barrier.
cellis•4mo ago
Are they trying to imply that high fat diets in humans similarly affect brain autophagy? That seems like quite the causal stretch given the vastly more complex metabolic architecture of humans.
trallnag•4mo ago
I'm don't see where the authors are making this implication.
cosmin800•4mo ago
I was expecting a mouse at least. Aren't these insects supposed to be feeding on fruits? Why feed them ribeyes?
trallnag•4mo ago
Coconut oil. And fruit flies do need fats for proper development.
No1•4mo ago
Whenever you see a "high-fat diet" study, you can usually translate that to "hypercaloric diet" study, and this one is no exception.

One fly food was 8% glucose (.308 kcal/g) and the other was 8% glucose + 20% coconut oil (.308 kcal/g + .7136 kcal/g = 1.0216 kcal/g) leaving the high-fat arm with 332% of the caloric density of the standard fly food diet. The discrepancy clouds how much of the observed effect is due to the coconut oil, and how much is due to the difference in caloric density.

I looked into how well fruit flies self-regulate caloric consumption, but all that I could find was related to carbohydrates and protein. It would seem that fruit flies don't typically eat much in the way of fats, presenting another confounder in the results.

pcthrowaway•4mo ago
In fruit flies
profstasiak•4mo ago
who cares? I can eat a ribeye steak and feel my hippocampus waking up from a glucose-infested coma. And no fruit fly will convince me otherwise!
ceving•4mo ago
If you eat more protein than you need, the excess is converted into glucose.
teytra•4mo ago
But note that it actually takes energy to break down the protein.

If you eat 100 kcal protein your body burns 20-30 kcal to process it. And you will feel more satiated than with the same amount of carbs.

hshdhdhj4444•4mo ago
Any evidence behind your numbers and claims?
trallnag•4mo ago
I wonder if there is a difference based on the length of the ingested fatty acids. Currently I ingest around 90 grams of MCTs per day.
hshdhdhj4444•4mo ago
The goal of this study is to suggest a mechanism for a high fat diet and memory issues, not to prove that the link exists which has been shown elsewhere.