Randomized controlled trial: https://en.wikipedia.org/wiki/Randomized_controlled_trial
Glossary of experimental design: https://en.wikipedia.org/wiki/Glossary_of_experimental_desig...
> Multi-arm multi-stage (MAMS) platform trials by the MRC Clinical Trials Unit at UCL — an overview of the advantages of MAMS trials, with teaching material
Is this like multi-armed bandit which marketing runs instead of A/B sometimes?
Multi-armed bandit: https://en.wikipedia.org/wiki/Multi-armed_bandit
> Cluster randomized trials by the NIH Pragmatic Trials Collaboratory
Cluster randomized trials: https://en.wikipedia.org/wiki/Cluster-randomised_controlled_...
> Crossover trials by the Cochrane Training Handbook
Crossover study, Crossover Trial: https://en.wikipedia.org/wiki/Crossover_study
But that's a different usage of the word "Crossover" than "Crossover" as an observed process and method of adaptation and optimization?
Crossover (evolutionary algorithm) https://en.wikipedia.org/wiki/Crossover_(evolutionary_algori...
> We really could get more out of this data through international collaboration and through linked data (e.g. URIs for columns). See: "Open, and Linked, FDA data" https://github.com/FDA/openfda/issues/5#issuecomment-5392966... and "ENH: Adverse Event Count / 'Use' Count Heatmap" https://github.com/FDA/openfda/issues/49
> With sales/usage counts, we'd have a denominator with which we could calculate relative hazard.
FHIR would be useful for sharing collected clinical data - for example vitals - with patients and their other providers if they choose.
FHIR could be useful for collecting chart data from clinical trial participants.
FHIR can be represented in JSON-LD, which is Linked Data in JSON such that no XML parsing is required.
Re: FHIR JSON-LD https://news.ycombinator.com/item?id=42230270 :
> /? awesome clinical open source: https://www.google.com/search?q=awesome+clinical+open+source
westurner•4mo ago
Randomized controlled trial: https://en.wikipedia.org/wiki/Randomized_controlled_trial
Glossary of experimental design: https://en.wikipedia.org/wiki/Glossary_of_experimental_desig...
> Multi-arm multi-stage (MAMS) platform trials by the MRC Clinical Trials Unit at UCL — an overview of the advantages of MAMS trials, with teaching material
Is this like multi-armed bandit which marketing runs instead of A/B sometimes?
Multi-armed bandit: https://en.wikipedia.org/wiki/Multi-armed_bandit
> Cluster randomized trials by the NIH Pragmatic Trials Collaboratory
Cluster randomized trials: https://en.wikipedia.org/wiki/Cluster-randomised_controlled_...
> Crossover trials by the Cochrane Training Handbook
Crossover study, Crossover Trial: https://en.wikipedia.org/wiki/Crossover_study
But that's a different usage of the word "Crossover" than "Crossover" as an observed process and method of adaptation and optimization?
Crossover (evolutionary algorithm) https://en.wikipedia.org/wiki/Crossover_(evolutionary_algori...
westurner•4mo ago
westurner•4mo ago
> We really could get more out of this data through international collaboration and through linked data (e.g. URIs for columns). See: "Open, and Linked, FDA data" https://github.com/FDA/openfda/issues/5#issuecomment-5392966... and "ENH: Adverse Event Count / 'Use' Count Heatmap" https://github.com/FDA/openfda/issues/49
> With sales/usage counts, we'd have a denominator with which we could calculate relative hazard.
westurner•4mo ago
FHIR would be useful for sharing collected clinical data - for example vitals - with patients and their other providers if they choose.
FHIR could be useful for collecting chart data from clinical trial participants.
FHIR can be represented in JSON-LD, which is Linked Data in JSON such that no XML parsing is required.
Re: FHIR JSON-LD https://news.ycombinator.com/item?id=42230270 :
> /? awesome clinical open source: https://www.google.com/search?q=awesome+clinical+open+source