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Ask HN: Opus 4.6 ignoring instructions, how to use 4.5 in Claude Code instead?

1•Chance-Device•39s ago•0 comments

We Mourn Our Craft

https://nolanlawson.com/2026/02/07/we-mourn-our-craft/
1•ColinWright•3m ago•0 comments

Jim Fan calls pixels the ultimate motor controller

https://robotsandstartups.substack.com/p/humanoids-platform-urdf-kitchen-nvidias
1•robotlaunch•6m ago•0 comments

Exploring a Modern SMTPE 2110 Broadcast Truck with My Dad

https://www.jeffgeerling.com/blog/2026/exploring-a-modern-smpte-2110-broadcast-truck-with-my-dad/
1•HotGarbage•7m ago•0 comments

AI UX Playground: Real-world examples of AI interaction design

https://www.aiuxplayground.com/
1•javiercr•7m ago•0 comments

The Field Guide to Design Futures

https://designfutures.guide/
1•andyjohnson0•8m ago•0 comments

The Other Leverage in Software and AI

https://tomtunguz.com/the-other-leverage-in-software-and-ai/
1•gmays•10m ago•0 comments

AUR malware scanner written in Rust

https://github.com/Sohimaster/traur
3•sohimaster•12m ago•1 comments

Free FFmpeg API [video]

https://www.youtube.com/watch?v=6RAuSVa4MLI
3•harshalone•12m ago•1 comments

Are AI agents ready for the workplace? A new benchmark raises doubts

https://techcrunch.com/2026/01/22/are-ai-agents-ready-for-the-workplace-a-new-benchmark-raises-do...
2•PaulHoule•17m ago•0 comments

Show HN: AI Watermark and Stego Scanner

https://ulrischa.github.io/AIWatermarkDetector/
1•ulrischa•18m ago•0 comments

Clarity vs. complexity: the invisible work of subtraction

https://www.alexscamp.com/p/clarity-vs-complexity-the-invisible
1•dovhyi•19m ago•0 comments

Solid-State Freezer Needs No Refrigerants

https://spectrum.ieee.org/subzero-elastocaloric-cooling
1•Brajeshwar•19m ago•0 comments

Ask HN: Will LLMs/AI Decrease Human Intelligence and Make Expertise a Commodity?

1•mc-0•20m ago•1 comments

From Zero to Hero: A Brief Introduction to Spring Boot

https://jcob-sikorski.github.io/me/writing/from-zero-to-hello-world-spring-boot
1•jcob_sikorski•20m ago•1 comments

NSA detected phone call between foreign intelligence and person close to Trump

https://www.theguardian.com/us-news/2026/feb/07/nsa-foreign-intelligence-trump-whistleblower
8•c420•21m ago•1 comments

How to Fake a Robotics Result

https://itcanthink.substack.com/p/how-to-fake-a-robotics-result
1•ai_critic•21m ago•0 comments

It's time for the world to boycott the US

https://www.aljazeera.com/opinions/2026/2/5/its-time-for-the-world-to-boycott-the-us
3•HotGarbage•22m ago•0 comments

Show HN: Semantic Search for terminal commands in the Browser (No Back end)

https://jslambda.github.io/tldr-vsearch/
1•jslambda•22m ago•1 comments

The AI CEO Experiment

https://yukicapital.com/blog/the-ai-ceo-experiment/
2•romainsimon•23m ago•0 comments

Speed up responses with fast mode

https://code.claude.com/docs/en/fast-mode
4•surprisetalk•27m ago•0 comments

MS-DOS game copy protection and cracks

https://www.dosdays.co.uk/topics/game_cracks.php
4•TheCraiggers•28m ago•0 comments

Updates on GNU/Hurd progress [video]

https://fosdem.org/2026/schedule/event/7FZXHF-updates_on_gnuhurd_progress_rump_drivers_64bit_smp_...
2•birdculture•29m ago•0 comments

Epstein took a photo of his 2015 dinner with Zuckerberg and Musk

https://xcancel.com/search?f=tweets&q=davenewworld_2%2Fstatus%2F2020128223850316274
14•doener•29m ago•2 comments

MyFlames: View MySQL execution plans as interactive FlameGraphs and BarCharts

https://github.com/vgrippa/myflames
1•tanelpoder•30m ago•0 comments

Show HN: LLM of Babel

https://clairefro.github.io/llm-of-babel/
1•marjipan200•31m ago•0 comments

A modern iperf3 alternative with a live TUI, multi-client server, QUIC support

https://github.com/lance0/xfr
3•tanelpoder•32m ago•0 comments

Famfamfam Silk icons – also with CSS spritesheet

https://github.com/legacy-icons/famfamfam-silk
1•thunderbong•32m ago•0 comments

Apple is the only Big Tech company whose capex declined last quarter

https://sherwood.news/tech/apple-is-the-only-big-tech-company-whose-capex-declined-last-quarter/
4•elsewhen•36m ago•0 comments

Reverse-Engineering Raiders of the Lost Ark for the Atari 2600

https://github.com/joshuanwalker/Raiders2600
2•todsacerdoti•37m ago•0 comments
Open in hackernews

New lab-grown human embryo model produces blood cells

https://www.cam.ac.uk/research/news/new-lab-grown-human-embryo-model-produces-blood-cells
93•gmays•3mo ago

Comments

typpilol•3mo ago
We're growing humans ?
castis•3mo ago
We are not. These are embryo-like structures. Not actual human embryos.
exe34•3mo ago
they have no mouth even if they want to scream.
jdonaldson•3mo ago
I'm an organ donor, and I have no problem giving my organs away after I'm quite positive I won't feel it. I think as long as there is no sensation, there is no pain, and certainly no formal concept of "self". But still, with matters of exploitation of our bodies, we should tread very very lightly.
exe34•3mo ago
that's an odd thing to bring up out of nowhere.
philipkglass•3mo ago
No. These don't develop like embryos and do not have to come from embryonic stem cells.

The structures differ from real human embryos in many ways, and cannot develop into them because they lack several embryonic tissues, as well as the supporting yolk sac and placenta needed for further development.

The human stem cells used to derive hematoids can be created from any cell in the body. This means the approach also holds great potential for personalised medicine in the future, by allowing the production of blood that is fully compatible with a patient’s own body.

frodo8sam•3mo ago
Perfect blood doping.

Kind of sad that that's the first thing that comes to mind...

nick49488171•3mo ago
Could you do this using current medicine by extracting and donating blood back to yourself after a week?
salamanderman•3mo ago
I'm pretty certain I read of people doing this in cycling tournaments.
bobbylarrybobby•3mo ago
Yes, Lance Armstrong did just that! https://www.usada.org/wp-content/uploads/ReasonedDecision.pd...
lawlessone•3mo ago
If that's what it takes get this technology everywhere i'm all for it lol.

An alternate Olympics where everyone is sponsored by medical companies :D

makr17•3mo ago
We have the Enhanced Games (https://en.wikipedia.org/wiki/Enhanced_Games), so we already have an alternative Olympics that definitely includes medical companies.
vintermann•3mo ago
As if the un-enhanced games weren't already getting closer to playing a game of chicken with your health on the line.
accurrent•3mo ago
I find it ironic that thats the first thing that comes to mind. I know people with rare blood groups, I think this could be huge for them.
djmips•3mo ago
I believe this could also be detected.
vintermann•3mo ago
Yes, it would be exactly the same as the original, "crude" blood doping of injecting your own blood.

For people talking about "augmented games" and such, bear in mind that one of the reasons it was banned was that young athletes were suddenly dying a lot from heart problems.

umeshunni•3mo ago
We've been growing humans since the beginning of time. This one is just in vitro.
measurablefunc•3mo ago
That's the technocratic endgame b/c a few people are rich enough to realize the potential for life extension using the same type of technology.
tifik•3mo ago
I know these are scientists and a 'Human embryo model' is a perfectly valid name, because it's a model of a human embryo, but it's a disaster from a marketing perspective. People will see 'human embryo' and it doesn't matter that it's just a model of one. You are now growing fetus-slaves.

Please call it something else.

Edit: they are calling it 'hematoids' and make it clear that it is quite different from an embryo. I'm not sure why it's compared to them in the first place then.

falcor84•3mo ago
Just on a philosophical level, is there anything that would make such embryos more "slaves" than embryos or fetuses in a womb? It's not as if in a womb they have any ability to assert conscious control over their environment, even if they had the cognitive and sensorial capacity.
pseudosaid•3mo ago
it wouldnt matter because of the context. It is expected that an embryo grows into a baby that is born. The very delaying of that expectation that denotes the slave label. Preventing the natural progression is a retardation of freedom. Since these embryo units are designed and purpose built, they are no more slave than the native embryo. If these designer embryos have capacity to develop further on their own, then there is an argument and correlation to be made.
Terr_•3mo ago
> is there anything that would make such embryos more "slaves" than embryos or fetuses in a womb?

Arguably much-less-so, given the complicated and morally-ambiguous mechanics of primate gestation [0] where a fetus in the womb exercises a degree of biochemical control and extortion over the mother.

[0] https://aeon.co/essays/why-pregnancy-is-a-biological-war-bet...

voxl•3mo ago
The hilarity of the very first comment I read after this one being someone complaining that this is the work of the anti christ and nothing will be sacred anymore.
burnte•3mo ago
Bryan Johnson will be getting these transfused into himself ASAP.
socrateswasone•3mo ago
Oh goody. Living human tissue, mimicking an embryo if not a baby, without consciousness or soul, grown and molded for our purposes and pleasures in a lab. This is excellent news everyone. A clear sign that we're winning the fight against the Antichrist (per Peter Thiel). It does kind of make you wonder though, what life is going to be like when absolutely nothing is sacred.
inglor_cz•3mo ago
"absolutely nothing is sacred."

There is no shortage of taboos in modern society, only the concrete focus shifts as generations change. Some things lose their sacredness and others gain it.

It was probably completely safe to draw a Muhammad cartoon and sign it in the West of 1950. Doing this now is a recipe for spending the rest of your life under police protection.

The explosion of hate speech laws all over the West is another instance thereof, though much less sanguinary.