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Semaglutide loses patent protection in '26 in India, Canada, Brazil and Turkey

https://www.iqvia.com/locations/emea/blogs/2025/07/off-patent-semaglutide
15•JumpCrisscross•2h ago

Comments

ReptileMan•2h ago
Somewhat irrelevant at this point. The peptides are sold freely in other countries as substances with which to experiment in petri dishes. Not for use on humans. I repeat - not for use on humans.
asdff•3m ago
The worst thing about these drugs hitting the pharma market in recent years is that it has sucked the air out of the room for other investment due to their immense profitability. So much cutting edge talent is being squandered to work on these weight loss drugs because they pay the bills better than solving rare disease. I've heard a direct quote from a pharma product manager in person: "we don't look for cures, we look for treatments." You know, because cure implies a one time payment.

Talk about perverse incentive.

Art Must Act

https://aeon.co/essays/harold-rosenberg-exhorted-artists-to-take-action-and-resist-cliche
1•tintinnabula•4m ago•0 comments

The Great Butterfly Heist

https://www.theguardian.com/global/2025/oct/04/great-butterfly-heist-how-collector-stole-thousand...
1•lermontov•5m ago•0 comments

E-Waste Recycling with Deep Eutectic Solvents

https://www.descycle.com/technology
1•dillonshook•8m ago•0 comments

Intellectualism Has Hampered Generative Art (2018)

https://www.tylerxhobbs.com/words/intellectualism-has-hampered-generative-art
1•aaronbrethorst•9m ago•0 comments

Vault of Horror – The Inside Mac cover you never saw

https://folklore.org/Vault_of_Horror.html
1•stmw•9m ago•0 comments

Kanchha Sherpa, last surviving member of first team to scale Everest, dies 92

https://www.pbs.org/newshour/world/kanchha-sherpa-last-surviving-member-of-history-making-mount-e...
1•1659447091•12m ago•1 comments

Death by a Thousand Reports

https://datamethods.substack.com/p/death-by-a-thousand-reports
1•zekrom•13m ago•0 comments

The Status Trap in Tech

https://datamethods.substack.com/p/the-status-trap-in-tech
1•zekrom•14m ago•0 comments

Book review: The game that never ends: How lawyers shape the videogame industry

https://networks.h-net.org/group/reviews/20126596/xiao-mailland-game-never-ends-how-lawyers-shape...
1•hhs•15m ago•0 comments

Where AI Coding Agents Go to Die

https://chatbotkit.com/reflections/where-ai-coding-agents-go-to-die
1•_pdp_•18m ago•0 comments

Too many scientific 'discoveries' get discredited

https://www.japantimes.co.jp/commentary/2025/10/01/world/scientific-discoveries-get-discredited/
1•PaulHoule•18m ago•0 comments

Ask HN: Should I still not upgrade to tahoe (macOS 26)?

1•nidnogg•20m ago•0 comments

From Web2 to Web3: Building Decentralized Front Ends with Wagmi

https://jsdev.space/wagmi-react/
1•javatuts•30m ago•0 comments

Is creative destruction on the decline?

https://www.ft.com/content/93f0fc4a-eab5-4364-835a-15530379436f
1•hhs•33m ago•0 comments

End of the World?

1•Toby1VC•35m ago•0 comments

Let's Build the GPT Tokenizer: A Complete Guide to Tokenization in LLMs

https://www.fast.ai/posts/2025-10-16-karpathy-tokenizers
8•jph00•43m ago•0 comments

Show HN: IT Flashcards – 5k Quizzes to Master 2,100 Tech Interview Questions

2•emmanol•48m ago•0 comments

Internal Amazon Documents Warned AI Startups Are Delaying AWS Spending

https://www.businessinsider.com/amazon-ai-startups-delaying-aws-spending-2025-10
2•walterbell•49m ago•0 comments

My perfect Music app doesn't exist

https://hicks.design/journal/my-perfect-music-app-doesnt-exist
3•vincelt•51m ago•0 comments

Howard Johnson, Permanent Magnet Motor, 1985, (patent expired 2006)

http://www.rexresearch.com/johnson/1johnson.htm
1•thro1•57m ago•1 comments

Nvidia DGX Spark and Apple Mac Studio = 4x Faster LLM Inference with EXO 1.0

https://blog.exolabs.net/nvidia-dgx-spark/
14•edelsohn•1h ago•3 comments

Physicists inadvertently generated the shortest X-ray pulses ever observed

https://theconversation.com/our-team-of-physicists-inadvertently-generated-the-shortest-x-ray-pul...
3•gmays•1h ago•0 comments

Show HN: The Rift – AI Short Movie

https://www.youtube.com/watch?v=R2M9dT4wPf0
1•modinfo•1h ago•0 comments

Lead Limited Brain and Language Development in Neanderthals and Other Hominids?

https://today.ucsd.edu/story/did-lead-limit-brain-and-language-development-in-neanderthals-and-ot...
17•gmays•1h ago•1 comments

Nat traversal, and how we're improving it

https://tailscale.com/blog/nat-traversal-improvements-pt-1
1•crcastle•1h ago•0 comments

New Credit Fraud Fears Raise More Worries About Regional Banks

https://www.wsj.com/finance/banking/new-credit-fraud-fears-raise-more-worries-about-regional-bank...
2•zerosizedweasle•1h ago•0 comments

Fly through Gaia's 3D map of stellar nurseries

https://www.esa.int/Science_Exploration/Space_Science/Gaia/Fly_through_Gaia_s_3D_map_of_stellar_n...
3•sohkamyung•1h ago•0 comments

From 2028: EU expands USB-C mandate to chargers

https://www.heise.de/en/news/From-2028-EU-expands-USB-C-mandate-to-chargers-10773444.html
3•ahlCVA•1h ago•0 comments

How the US govt can build AI surge capacity

https://www.iaps.ai/research/building-ai-surge-capacity
2•yieldinglylow•1h ago•0 comments

Changing my mind on developer onboarding: code vs. product

https://olshansky.info/thoughts/2025-10-16-changing-my-thought-on-developer-onboarding
2•Olshansky•1h ago•0 comments