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Early pandemic HIV-1 integration site preferences differ across anatomical sites

https://www.nature.com/articles/s43856-025-01146-5
3•PaulHoule•3h ago

Comments

ggm•2h ago
> HIV can stay in the body for life by hiding inside the DNA of infected cells. This makes it hard to completely remove the virus, even with strong treatment. In this study, researchers explored whether HIV hides in different ways depending on where in the body the infected cells are found.

where "are found" is, and where "is" is, are different. If they mean ONLY found, despite exhaustive testing, thats quite different to "we looked under the lamppost (brain) because thats what we had (post mortem) to look at"

Programming with Less Than Nothing

https://joshmoody.org/blog/programming-with-less-than-nothing/
1•signa11•1m ago•0 comments

Documentation That Updates Itself from Your Code and Commits

https://docdriven.com
1•lion_bytes•1m ago•0 comments

Tesla profit falls short despite record sales

https://www.reuters.com/business/autos-transportation/teslas-record-revenue-tops-forecasts-tax-cr...
1•1vuio0pswjnm7•3m ago•0 comments

AI Workers Are Putting in 100-Hour Workweeks to Win the New Tech Arms Race

https://www.wsj.com/tech/ai/ai-race-tech-workers-schedule-1ea9a116
1•doener•10m ago•0 comments

What GPU pricing can tell us about how the AI bubble will pop

https://www.ft.com/content/d49707ae-5d6b-473e-9e2b-487d318e6fe9
2•KnuthIsGod•11m ago•0 comments

Our Voice-AI Assistant Hit Unit Profit – Thanks to Haiku 4.5

https://www.indiehackers.com/post/our-voice-ai-assistant-hit-unit-profit-thanks-to-haiku-4-5-8CKe...
1•Norcim133•12m ago•0 comments

Convention over LLM (CoL) – A novel approach to coding

1•pyeri•13m ago•0 comments

Meta's Alexandr Wang on why the AI team just laid off 600 workers

https://www.businessinsider.com/alexandr-wang-meta-superintelligence-labs-layoffs-memo-2025-10
2•nedsma•19m ago•0 comments

AI capitalism provokes the next financial crisis (German)

https://www.boersen-zeitung.de/konjunktur-politik/ki-kapitalismus-provoziert-naechste-finanzkrise
2•doener•20m ago•0 comments

Motor Temperature Estimation Without a Sensor

https://build-its-inprogress.blogspot.com/2019/10/motor-temperature-estimation-without.html
1•pillars•23m ago•0 comments

Reflections on My Tech Career – Part 1

https://randomascii.wordpress.com/2025/10/22/reflections-on-my-tech-career-part-1/
1•nikbackm•26m ago•0 comments

What it costs to keep up with the A.I. boom

https://messaging-custom-newsletters.nytimes.com/dynamic/render
1•doener•27m ago•0 comments

OpenAI, ARIA, and SEO: Making the Web Worse

https://adrianroselli.com/2025/10/openai-aria-and-seo-making-the-web-worse.html
1•tobr•30m ago•0 comments

Mosquitoes found in Iceland for first time after record heat

https://www.bbc.com/news/articles/clyz3vv62pgo
1•tellarin•33m ago•0 comments

Ask HN: Would you like some help with your OSS project?

1•seph-reed•37m ago•0 comments

A new API for interrupt-aware spinlocks

https://lwn.net/Articles/1039374/
2•pykello•56m ago•0 comments

Andreessen Horowitz lines up $10B for next wave of tech bets

https://www.ft.com/content/92262343-b4e0-406e-8a01-2199d45d719e
3•aarghh•1h ago•0 comments

Measured AI

https://notetoself.studio/post/measured-ai/
2•SLHamlet•1h ago•0 comments

Fixing UUIDv7 (for database use-cases)

https://brooker.co.za/blog/2025/10/22/uuidv7.html
3•mebcitto•1h ago•0 comments

Nobody Is Buying Apple's iPhone Air [video]

https://www.youtube.com/watch?v=bpz_DfxSnsc
3•behnamoh•1h ago•0 comments

The mild mannered Englishman who was the most prolific ghost hunter

https://lithub.com/the-mild-mannered-englishman-who-was-the-worlds-most-prolific-ghost-hunter/
6•gmays•1h ago•0 comments

Too Much Choice, Not Enough Verification

https://www.aivojournal.org/too-much-choice-not-enough-verification/
2•businessmate•1h ago•1 comments

Why Everyone Is Leaving New Zealand [video]

https://www.youtube.com/watch?v=F_VUBpALcVE
7•l8rlump•1h ago•2 comments

Archaeology of the IBM PC110 [video]

https://www.youtube.com/watch?v=8Uja7g9hQlo
2•gilad•1h ago•0 comments

Fed Lost Access to Private Jobs Data Ahead of Government Shutdown

https://www.wsj.com/economy/central-banking/fed-lost-access-to-private-jobs-data-ahead-of-governm...
3•zerosizedweasle•1h ago•0 comments

I built Parall – a native macOS app to run multiple instances of any app

https://parall.app/
2•IGHOR•1h ago•1 comments

Mapping smoking rates by state with Matplotlib and geopandas

https://aaronjbecker.com/posts/matplotlib-choropleth-mapping-smoking-rates/
1•aaronjbecker•1h ago•0 comments

Musk Hijacks Tesla Earnings Call to Pitch $1T Pay Plan

https://www.bloomberg.com/news/articles/2025-10-22/musk-hijacks-tesla-earnings-call-to-pitch-1-tr...
6•zerosizedweasle•1h ago•1 comments

Tesla's increased costs outweighed its revenue growth

https://www.cnbc.com/2025/10/23/cnbc-daily-open-teslas-increased-costs-outweighed-its-revenue-gro...
11•zerosizedweasle•1h ago•0 comments

Devman's RaaS launch: the affiliate who aims to become the boss

https://analyst1.com/devmans-raas-launch-the-affiliate-who-aims-to-become-the-boss/
1•ropable•1h ago•0 comments